KEGG   MODULE: sew_M01000
Entry
sew_M01000        Pathway   Module                                 
Name
GDP-Man biosynthesis, Fru-6P => GDP-Man
Definition
(K01809,K28465,K15916,K16011) (K17497,K01840,K15778,K16881) (K00966,K00971,K16011,K16881)
Diagram
sew_M01000  GDP-Man biosynthesis, Fru-6P => GDP-Man
sew_M01000

Class
Pathway modules; Glycan metabolism; Nucleotide sugar biosynthesis
Pathway
sew00520  Amino sugar and nucleotide sugar metabolism
sew00051  Fructose and mannose metabolism
sew01250  Biosynthesis of nucleotide sugars
sew01100  Metabolic pathways
Organism
Salmonella enterica subsp. enterica serovar Schwarzengrund [GN:sew]
Gene
SeSA_A1566  manA; mannose-6-phosphate isomerase, class I [KO:K01809]
SeSA_A2311  putative phosphomannomutase [KO:K01840]
SeSA_A2312  mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [KO:K00971]
SeSA_A2337  cpsG; phosphomannomutase [KO:K01840]
SeSA_A2338  cpsB; mannose-1-phosphate guanylyltransferase [KO:K00971]
Reaction
Compound
C00085  D-Fructose 6-phosphate
C00275  D-Mannose 6-phosphate
C00636  D-Mannose 1-phosphate
C00096  GDP-mannose
Reference
  Authors
Akutsu J, Zhang Z, Morita R, Kawarabayasi Y
  Title
Identification and characterization of a thermostable bifunctional enzyme with phosphomannose isomerase and sugar-1-phosphate nucleotidylyltransferase  activities from a hyperthermophilic archaeon, Pyrococcus horikoshii OT3.
  Journal
Extremophiles 19:1077-85 (2015)
DOI:10.1007/s00792-015-0779-5
Reference
  Authors
Kuettel S, Wadum MC, Guther ML, Marino K, Riemer C, Ferguson MA
  Title
The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei.
  Journal
Mol Microbiol 84:340-51 (2012)
DOI:10.1111/j.1365-2958.2012.08026.x
KO module
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