Salmonella enterica subsp. enterica serovar Typhi P-stx-12: STBHUCCB_1440
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Entry
STBHUCCB_1440 CDS
T01741
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sex
Salmonella enterica subsp. enterica serovar Typhi P-stx-12
Pathway
sex00300
Lysine biosynthesis
sex00550
Peptidoglycan biosynthesis
sex01100
Metabolic pathways
sex01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sex00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
STBHUCCB_1440
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
STBHUCCB_1440
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
STBHUCCB_1440
Enzymes [BR:
sex01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
STBHUCCB_1440
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEZ43904
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Position
146377..147735
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AA seq
452 aa
AA seq
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MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKAN
GAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTASNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFS
PNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATL
AAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHLQVGEAAKAAGIDRVLSTGKLSQVISHASGVGEHFADKAALIARLHAL
LQEQPMMTILVKGSRSAAMEDVVHALQEKGSC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagcaaaattgccgatgtccttggcgccgaacaccgcggggcg
gatctcacgctcgatacggtcattaccgacacacggaaagtgacgccgggatgcctgttc
gtggcgctgaaaggggaacgctttgatgcgcatgattttgctgataaagcaaaagcgaac
ggcgctggcgccctgctggtcagtcgtcctctggatatcgatcttccgcaggtgattgta
aaagacacgcgtcaggcatttggccaactggccgcctgggtacgtatgcaggtaccggcg
cgggtggtggcgttaaccggttcgtccggcaaaacctcggtcaaagagatgaccgccgcg
attcttagccagtgcggaaatactttgtataccgcaagcaattttaacaacgacatcggc
gtgccgataacgctgctgcgcttaaaccatgattatgactatgcggtgatcgagttaggc
gctaatcaccagggagaaatcgcctggaccgttagcctgacgcgcccggaagcggcgctg
gtcaataacctggcggcggcgcatctggaaggtttcggctcgctggccggcgtggcgaaa
gcgaaaggcgaaatctataccggtttgcctgagaacggtatcgcgattatgaatgccgat
aataatgactggctgaactggcaaagcattattggcgatcgtcaggtgtggcgcttttcg
ccgaatgcggcaaacagcgactttaccgctgcgaatatccacgtgacgtcacacggtacc
gaatttaccctgcaaacgccgatgggcagcattgatgtgctgctgccgttgccggggcgg
cacaatattgccaacgcgctggcggccgctgctttatcaatggcggtgggggcgacgctg
gcggcggttaaagcagggctggcggcgttaaaagccgtacccgggcgtctgttcccgatt
caactaagtgaaaaccaactggtactggatgacgcttataacgccaacgtcggttcgatg
accgccgcagtgcaggtcctttctgaaatgcccggctaccgcgtgctggtggtaggcgat
atggccgagctgggcgcagaaagcgaagcgtgccacctccaggttggcgaggccgcaaaa
gcggcgggtattgatcgcgtgttaagcaccggaaaactcagtcaggttatcagccacgcc
agcggcgtcggcgaacattttgccgataaagccgcgctcattgcgcgtttacacgctctg
cttcaggagcaaccgatgatgactattttagtgaaaggatcacgcagcgccgcgatggaa
gatgtggttcatgcgttacaggagaaaggttcatgttag
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