KEGG   Streptomyces explomaris: SLV14_006428
Entry
SLV14_006428      CDS       T11122                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
sexp  Streptomyces explomaris
Pathway
sexp00860  Porphyrin metabolism
sexp01100  Metabolic pathways
sexp01110  Biosynthesis of secondary metabolites
sexp01120  Microbial metabolism in diverse environments
sexp01240  Biosynthesis of cofactors
Module
sexp_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:sexp00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    SLV14_006428 (cobA)
Enzymes [BR:sexp01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     SLV14_006428 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     SLV14_006428 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     SLV14_006428 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C Shikimate_DH DUF7504 Radical_SAM
Other DBs
NCBI-ProteinID: UYB43457
LinkDB
Position
7347977..7349209
AA seq 410 aa
MAEHVAEHAAYPVGLRLSGRRVVVLGAGQVAQRRLPSLVAAGADVLLISPSATPSVEAMA
DAGEVRWERRRYQDGDLDGAWYALISTDDSAANAAASQEAEDRRVWCVRSDDAEAATAWT
PATGRSEGVTVAVLTGRDPRRSAAVRDAIVEGLRDGSIAAPHHRRPHTPGVALVGGGPGD
PDLITVRGRRLLAEADVVIADRLGPRDLLAELPPHVEVIDAAKIPYGRFMAQEAINNALI
EHAKAGKAVVRLKGGDPFVFGRGMEEAQALAEAGIPCTVVPGISSTISVPGAAGIPVTHR
GVAHEFTVVSGHVAPDDERSLVDWPALAKLRGTLVVLMGVENSGAIAAKLVEHGRAADTP
AAVIQEGTTAAQRRVDATLATLGETVRAEGVRPPAVIVIGEVVAVAPTHR
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggctgagcacgtcgccgaacacgctgcctaccccgtcggactgcggctgtccggccgc
cgggtggttgtcctgggcgccgggcaggtcgcccagcgccggctcccctccctcgtcgcc
gccggcgccgatgtcctgctgatctccccgtccgccaccccgtccgtcgaggcgatggcc
gacgccggcgaggtccgctgggagcgccgccgctaccaggacggcgacctcgacggtgcc
tggtacgcgctgatctccaccgacgactcggcggccaacgccgccgcgtcccaggaggcc
gaggaccgccgggtgtggtgcgtacgctccgacgacgccgaggcggccaccgcctggacc
ccggccaccggccgcagcgagggcgtcaccgtcgcggtgctcaccggccgcgacccgcgc
cgctccgccgccgtacgcgacgccatcgtcgagggcctccgggacggcagcatcgccgcc
ccgcaccaccgccgcccgcacaccccgggagtggccctggtcggcggcggccccggcgac
cccgacctgatcaccgtccgcggccgccggctgctcgccgaggccgacgtggtcatcgcc
gaccgcctcggcccccgcgacctcctcgccgaactcccgccgcatgtcgaggtcatcgac
gcggcgaagatcccctacggccgtttcatggcccaggaggccatcaacaacgcgctgatc
gagcacgccaaggccggcaaggccgtggtccggctcaaggggggcgacccgttcgtcttc
ggccgcggcatggaggaggcccaggctctcgccgaggccgggatcccctgcacggtcgtc
cccggcatctccagcaccatctcggtgcccggcgccgccggtatccccgtcacccaccgc
ggcgtcgcccacgagttcaccgtcgtcagcggccatgtcgcccccgacgacgagcgctcg
ctggtggactggccagcgctcgccaagctgcgcggcaccctcgtcgtcctgatgggcgtg
gagaacagcggcgccatcgccgccaagctcgtcgagcacggccgcgccgccgacaccccc
gccgccgtcatccaggaggggaccaccgcggcccagcgccgcgtcgacgccaccctcgcg
acgctcggcgagaccgtacgggccgagggcgttcgccccccggcggtcatcgtcatcggt
gaggtcgtcgccgtagcacctacccacaggtaa

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