Streptomyces pratensis: Sfla_3225
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Entry
Sfla_3225 CDS
T01647
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sfa
Streptomyces pratensis
Pathway
sfa00280
Valine, leucine and isoleucine degradation
sfa00640
Propanoate metabolism
sfa00785
Lipoic acid metabolism
sfa01100
Metabolic pathways
sfa01110
Biosynthesis of secondary metabolites
sfa01210
2-Oxocarboxylic acid metabolism
Module
sfa_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Sfla_3225
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Sfla_3225
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Sfla_3225
Enzymes [BR:
sfa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Sfla_3225
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
XFP_N
Motif
Other DBs
NCBI-ProteinID:
ADW04646
UniProt:
A0A8D3WJ77
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Position
3733848..3735011
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AA seq
387 aa
AA seq
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MTVQELPGAAAYRPTPPPAWKPLTDPAPLLPDPEPFRVLGTDAAADADPELLLRLYAELV
RGRRYNAQATALTKQGRLAVYPSSTGQEACEIAAALVLEDRDWLFPSYRDTLAAVARGLD
PVEALTLLRGDRHTGYDPREHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDG
GTSEGDFHEALNFAAVWRAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVD
GNDAAAMHQVLSEAVARARRGEGPTLVEAVTYRMDAHTNADDATRYRGDSEVETWRAHDP
IVLLERELTGRGLLDEDGMTAVREEAERMAEGLREQMNADPVLDPMDLFSHVYEEQTGQL
REQADQLRVELDAEHGPHDGHGAEGVR
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgacggtccaggagctgcccggcgcagccgcctaccggcccacgccgcccccggcctgg
aagccgctcacggatcccgcgccgctgctcccggaccccgagccgttccgcgtgctcggt
accgatgccgcagcggatgccgaccccgagctgctgctgaggctctatgccgagctggtc
cgcggtcggcggtacaacgcccaggccaccgcactcaccaagcagggcaggctcgcggtg
tacccgtcgagcaccggccaggaggcatgtgagatcgccgcggcactcgtgctggaagac
cgggactggctcttccccagctaccgcgacaccctggccgcggtggcgcgtggcctggac
ccggtcgaggcactgacgttgctgcggggcgaccgccacaccgggtacgacccgcgcgag
caccgcatcgccccgctgtgcacccccctggccacccagttgccccatgccgtggggctg
gcgcacgcggcgcgcctcaagggcgacgacgtggtggccctcgcgatggtcggcgacggc
gggacgagtgagggcgatttccacgaggcactgaatttcgcggctgtctggcgggcgccg
gtcgtgttcctcgtacagaacaacggcttcgcgatctccgtgcccttggcgaagcagacc
gcggcgccgtccctcgcgcacaaggccgtgggttacggcatgccggggcgcctggtcgac
ggcaacgacgcggcagcgatgcaccaggtgttgagcgaggctgtggcgcgggccaggcgc
ggggagggcccgacgctggtcgaggccgtcacctaccgcatggacgcccacacgaacgcc
gacgacgccacccgttaccgcggtgacagcgaggtggagacgtggcgcgcgcatgatccc
atcgtgcttctcgagcgggagctgaccgggcgggggctgctggacgaggacggcatgacg
gcggtgcgggaggaggccgagcggatggcggagggtctgcgggagcagatgaacgccgat
ccggttctcgacccgatggatctgttctcccatgtctacgaggagcagacgggtcagctg
cgggaacaggcggaccagttgcgggtcgagttggacgcggagcacggtccgcacgacggg
cacggcgcggagggagtccgatga
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