Streptomyces pratensis: Sfla_4269
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Entry
Sfla_4269 CDS
T01647
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfa
Streptomyces pratensis
Pathway
sfa00790
Folate biosynthesis
sfa01100
Metabolic pathways
sfa01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Sfla_4269
Enzymes [BR:
sfa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Sfla_4269
6.3.2.17 tetrahydrofolate synthase
Sfla_4269
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADW05677
UniProt:
A0A8D3WJ75
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Position
4939443..4940966
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AA seq
507 aa
AA seq
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MSEPRPSDRHDASDPDDTFAEIVDEETQRDPDLAVIEAGSRTLRTQSGPPQGEAVPDRPA
DPETDRALREVEQELAGRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTA
RMIEALLNALDLRTGRYTSPHVQSITERISLDGAPIDAERFIETYNDVKPYVEMVDAQQP
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDASVAVVTPISLDHTDRLG
STPAEIAGEKSGIVKQDATVILAQQPVDAAQVMLKKAVEVDATVAREGMEFGIVSREIAV
GGQLLTLRGLGGEYDNIFLPLYGAHQAHNAVVALAAVEAFFGIGAEQARSLDVEAVRKAF
LSVLSPGRLEVVRSSPTVVLDAAHNPAGALAASEGISEAFSFSRLIGVVGTSGDKDVRGL
LEAFEPIFAEIVVTQNSSPRAMDADELAALAVEVFGNERVQVEPRLDDALEAAITLAEEE
AEYAGAGVLVTGSVITVGEARLLLGRR
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgcccttcagaccggcacgacgcgtccgatcccgacgacaccttcgcg
gagatcgtcgacgaggagacccagcgcgatcccgacctggcggtgatcgaggccgggagc
cgcacgctgcgcacccagtcgggcccgccgcagggcgaggcggttcccgaccgtcccgcc
gaccccgagaccgaccgcgcgctgcgcgaggtggagcaggagctcgcgggccgctggggc
gagaccaagctcgaaccgtccgtgacccgtatcgcggctctgatggacgtgctgggcgag
ccccagcgcgcctacccgtcgatccacatcacggggacgaacggcaagaccagcacggcg
cgcatgatcgaggccctgctgaacgccctcgacctgcgcaccggccgctacacctccccg
cacgtccagtcgatcaccgagcggatcagcctggacggcgccccgatcgacgccgagcgc
ttcatcgagacctacaacgacgtcaagccgtacgtcgagatggtcgacgcccagcagccc
taccgcctctcgttcttcgaggtgctgaccggcatggcgtacgcggccttcgcggacgcg
ccggtcgacgtcgcggtcgtcgaggtcggcatgggaggcacctgggacgcgacgaacgtc
atcgacgcctcggtcgccgtcgtcacccccatctccctggaccacaccgaccgcctcggc
tccacgcccgccgagatcgccggcgagaagtccggcatcgtcaagcaggacgcgacggtg
atcctggcgcagcagccggtcgacgccgcgcaggtcatgctgaagaaggccgtcgaggtg
gacgccacggtggcccgcgagggcatggagttcggcatcgtctcccgcgagatcgcggtc
ggcggccagctgctgaccctgcggggcctgggcggcgagtacgacaacatcttcctgccg
ctctacggggcgcaccaggcgcacaacgccgtggtggcgctcgccgccgtcgaggcgttc
ttcggcatcggcgcggagcaggcccgcagtctcgacgtggaggcggtccgcaaggccttc
ctgtccgtcctctcgccgggccgcctggaagtcgtcaggtccagcccgaccgtcgtcctg
gacgcggcgcacaacccggccggcgcactcgccgcctccgaggggatctccgaggcgttc
agcttctcccggctgatcggggtcgtcggcacgagcggcgacaaggacgtccgggggctc
ctcgaagccttcgagccgatcttcgccgagatcgtcgtcacccagaactccagcccgcgt
gccatggacgcggacgagcttgccgccctcgccgtcgaggtcttcggcaacgagcgcgtc
caggtcgagccacgcctggacgacgccctggaggcggcgatcaccctcgccgaggaagag
gccgagtacgcgggcgccggggtcctggtgaccggatccgtgatcacggtcggcgaggcc
cggctgcttctgggaaggcgctga
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