Streptomyces fradiae: CP974_14565
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Entry
CP974_14565 CDS
T07648
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sfb
Streptomyces fradiae
Pathway
sfb00280
Valine, leucine and isoleucine degradation
sfb00640
Propanoate metabolism
sfb00785
Lipoic acid metabolism
sfb01100
Metabolic pathways
sfb01110
Biosynthesis of secondary metabolites
sfb01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sfb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CP974_14565 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CP974_14565 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP974_14565 (pdhA)
Enzymes [BR:
sfb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CP974_14565 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QEV13005
LinkDB
All DBs
Position
complement(3278828..3280024)
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AA seq
398 aa
AA seq
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MTVDSTAARQPRRGGTSSSGTKAAGGATKRAARAKKPRSSSSEPPLVQLLTPEGERVQHP
DYDVDLTPEELRGLYRDMVMTRRFDGEATALQRQGELGLWASLLGQEAAQIGSGRALRDD
DYVFPTYREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNSNNFHLYTIVLGSQTLHATGYA
MGVTRDGADSAVLAYFGDGASSQGDVNESFVFSAVYNAPVVFFCQNNQWAISEPTEKQTR
VPLYQRAQGFGFPGVRVDGNDVLACLAVTRWALERARRGEGPTLIEAFTYRMAAHTTSDD
PTRYRHDEERAAWEAKDPILRLRRHLEAQGHADASWFEELEVESEALGKHVREVVRAMPV
PEHMAMFDNVYADGHALVDEERAQFAAYQASFANGEAE
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggacagcactgccgcgcgccagccgcgacgcggcggcaccagcagcagtggc
accaaagccgccggcggtgccaccaagcgcgccgcgcgcgcgaagaagccccggagttcc
agctccgagccgccgctcgtacagctgctgacgcccgagggcgagcgcgtccagcacccc
gactacgacgtcgacctgacccccgaggagctgcgcggcctctaccgcgacatggtgatg
acccgccgcttcgacggcgaggccaccgcgctccagcgccagggcgagctgggcctgtgg
gcctcgctgctcggccaggaggcggcgcagatcggctccggccgggcgctgcgcgacgac
gactacgtcttcccgacctaccgcgagcacggcgtggcctggtgccgcggggtcgacccg
acgaacctcctcggcatgttccgcggggtgaacaacggcggctgggaccccaacagcaac
aatttccacctgtacacgatcgtcctcggctcgcagaccctgcacgccaccggctacgcc
atgggcgtcaccagggacggcgcggactccgccgtgctcgcgtacttcggcgacggcgcc
tccagccagggcgacgtcaacgagtcgttcgtcttctccgcggtctacaacgccccggtc
gtgttcttctgccagaacaaccagtgggccatctccgagcccaccgagaagcagacccgc
gtcccgctgtaccagcgcgcgcagggcttcggcttccccggcgtccgcgtcgacggcaac
gacgtcctcgcctgcctggccgtgacccgctgggcgctggagcgcgcccgccgcggcgag
ggcccgacgctcatcgaggcgttcacctaccgcatggccgcccacaccacctccgacgac
ccgacccgctaccggcacgacgaggagcgggccgcctgggaggcgaaggacccgatcctg
cgcctgcgccgtcacctggaggcccagggccacgccgacgcgtcctggttcgaggagctg
gaggtggagagcgaggccctcggcaagcacgtccgcgaggtcgtccgcgccatgcccgtt
ccggagcacatggcgatgttcgacaacgtgtacgcggacgggcacgcgctcgtcgacgag
gagcgcgcgcagttcgccgcctaccaggcgtccttcgcgaacggagaggccgagtaa
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