Streptomyces fradiae: CP974_29365
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Entry
CP974_29365 CDS
T07648
Name
(GenBank) pyruvate carboxyltransferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sfb
Streptomyces fradiae
Pathway
sfb00290
Valine, leucine and isoleucine biosynthesis
sfb00620
Pyruvate metabolism
sfb01100
Metabolic pathways
sfb01110
Biosynthesis of secondary metabolites
sfb01210
2-Oxocarboxylic acid metabolism
sfb01230
Biosynthesis of amino acids
Module
sfb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sfb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CP974_29365
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CP974_29365
Enzymes [BR:
sfb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CP974_29365
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
AP_endonuc_2
PTE
Motif
Other DBs
NCBI-ProteinID:
QEV15382
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Position
6706781..6707956
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AA seq
391 aa
AA seq
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MTVRPEDRPTRRVSVVDTTLRDGEQAPGNAMEPDEKVEMAQRIEALGVDVVEAAFPASSP
RDFEATRLIAQTLKRARLATFSRTTRQDVEVAVEAGGTGNHEVQLVATGSEIHLEHKRGI
TREQAVREVTDTVGFARALGVRHVSVGIEDASRGSDDLVRALCDGALDAGADCVILADTT
GCATPEEFGALVAKVRAWAPRPVRLSTHCHNDFGLSLANAVAGLVAGADEVQVTLGGIGE
RGGNTPLEELAALLAYKGGQYGLHTDIDTAGMYEAYTALRRVIRLEEPRNKPIFGRYAFG
TTAGIHQQGILSNPATYEYVEPARFGRERALLIGRHSGRTILRHLLDQLGVGTTDEQFTE
LYHRYITGREGSDSEDLAVVRDRLARELAGR
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgacggtgagaccggaagaccgcccgacccgccgggtctccgtggtcgacacgacgctg
cgggacggcgagcaggcccccggcaacgcgatggagcccgacgagaaggtggagatggcc
cagcgcatcgaggccctgggcgtcgatgtcgtggaggcggccttcccggcgtcgtccccg
agggacttcgaggcgacgcggctgatcgcccagaccctgaagcgcgcccgcctcgccacc
ttctcgcggacgacgcgccaggacgtggaggtcgccgtcgaggcgggcggcacgggcaac
cacgaggtgcagctcgtcgccacgggcagcgagatccatctggagcacaagcggggcatc
acccgcgagcaggccgtgcgggaggtcaccgacaccgtcggattcgcccgcgcgctcggc
gtccgccatgtgtcggtcgggatcgaggacgccagccggggcagcgacgacctggtgagg
gcgctctgcgacggcgctctcgacgccggggcggactgcgtcatcctcgccgacaccacg
ggatgcgccaccccggaggagttcggcgcgctggtggcgaaggtgcgcgcgtgggccccg
cgcccggtgcgcctctccacccactgccacaacgacttcgggctgtcgctggcgaacgcg
gtcgccggcctggtggccggcgccgacgaggtccaggtgaccctgggcggcatcggggag
cgcggcggcaacaccccgctggaggaactcgccgcgctcctcgcctacaagggcgggcag
tacggcctgcacaccgacatcgacaccgccggcatgtacgaggcgtacacggcgctgcgc
cgcgtcatccgcctggaggagccccgcaataagccgatcttcggccggtacgccttcggc
accaccgcgggcatccaccagcagggcatcctcagcaaccccgcgacgtacgagtacgtc
gaaccggcccggttcggccgcgagcgggccctcctcatcggccgccactcgggccgcacc
atcctgcggcatctgctggaccagctcggcgtcggcaccaccgacgagcagttcaccgag
ctgtaccaccggtacatcaccggacgggagggctccgacagcgaggacctcgccgtcgta
cgggaccggctcgcccgcgagctggccggccgctga
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