Spirochaeta africana: Spiaf_2381
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Entry
Spiaf_2381 CDS
T01811
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sfc
Spirochaeta africana
Pathway
sfc00290
Valine, leucine and isoleucine biosynthesis
sfc00770
Pantothenate and CoA biosynthesis
sfc01100
Metabolic pathways
sfc01110
Biosynthesis of secondary metabolites
sfc01210
2-Oxocarboxylic acid metabolism
sfc01230
Biosynthesis of amino acids
Module
sfc_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sfc_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sfc00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Spiaf_2381
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Spiaf_2381
Enzymes [BR:
sfc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
Spiaf_2381
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AFG38412
UniProt:
H9ULL9
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Position
2697368..2699209
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AA seq
613 aa
AA seq
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MPALRSLTNTAGRNMAGARALWRANGMKKEQFGKPIIAIANSFTQFVPGHAHLHDIGQDV
KRLIEEQGCFAAEFDTIAVDDGIAMGHGGMLYSLPSRELIADSIEYMVNAHCADALVCIS
NCDKITPGMMLAAMRLNIPTVFVSGGPMEAGVVGDRKYDLVDAMVMAADTSVDDDTLAAV
EENACPTCGSCSGMFTANSMNCLNEALGLALPGNGTVLATHVERRRLFEKAAARVVEVAR
EYYDNDNDAVLPRSIATKAAFMNAMSLDIAMGGSTNTVLHLLAIAREAGVDFTMQDIDQL
SRKVPCLSKVSPNSQYHIEDVHRAGGIMGILGELDRAGLLDTSVSRIDYPSLAAALDDWD
IAGSGRAAEASSTARAFYAAAPGGYRNLKLASQDARFKELDTDRAGGCIRSSAHAYYADG
GLAVLFGNLAENGCIVKTAGVDESIFRFTGTAKVFESQDDAVHGILNGQVAAGNVVIIRY
EGPKGGPGMQEMLYPTSYLKAMGLGKECALLTDGRFSGGTSGLSIGHASPEAAAGGAIAL
VEDGDTIEIDIPGRSINMRVSDSELEKRRAAQLARGDKAFTPHNRERQVSTALKVYASMA
TSADQGAYRQLPE
NT seq
1842 nt
NT seq
+upstream
nt +downstream
nt
atgcccgctttacgcagcctgaccaacaccgccggacgcaacatggccggtgcacgcgcg
ctgtggcgcgccaacggtatgaaaaaggaacagttcggcaaaccgataatcgccatcgcc
aactctttcacccagtttgttcccggccacgcccacctgcacgacatcggacaggatgtt
aagcgattgatcgaggaacagggctgcttcgccgccgagttcgataccattgcggtggac
gacgggattgcaatgggccacggggggatgctctacagcctgccaagccgcgagcttatt
gccgacagcatcgagtacatggtgaacgcccactgcgccgatgccctggtctgcatatcc
aactgtgacaagattaccccgggcatgatgctggccgccatgcgcctgaatatcccgacg
gtgtttgtatccggcggccccatggaggccggggttgtcggagaccggaaatacgacctg
gtggatgccatggtgatggctgccgataccagtgtcgatgacgacaccctggcggcagta
gaggaaaatgcctgcccgacctgcggcagctgctccgggatgtttaccgcaaactccatg
aactgtctgaacgaggccctggggctggcattgccgggaaacgggacggtactggctacc
catgttgaacgccgccggctgttcgaaaaggcggcggcgcgggtagtcgaggttgcccgc
gaatactatgacaacgacaatgacgcggtcctgccgcgctcgattgcaaccaaggccgcc
tttatgaacgccatgagcctggatattgccatgggcggcagcaccaacaccgtactgcac
ctgctggcgattgcacgcgaagccggtgtcgactttaccatgcaggatatcgaccagctg
tcgcgtaaggtaccctgcctctccaaggtcagccccaactcccagtaccacatagaggat
gtacaccgcgctggcgggatcatggggattctgggggaactggaccgggccgggctgctg
gataccagcgtctcgcggatcgactaccccagcctggccgccgcactggacgactgggat
attgccggcagcggccgggccgccgaggccagcagcaccgcgcgtgcgttctatgccgcc
gctcccggcggttatcgcaacctcaaactcgccagccaggatgcccgcttcaaggagctg
gacacagaccgggccggcggctgtatccgcagcagtgcgcacgcctactacgccgatggc
ggtctggccgtgctgtttggcaacctggcggagaacggctgtatcgtcaaaacagcaggg
gtcgatgagagtatcttcaggtttaccggtaccgcgaaggtcttcgaaagtcaggatgat
gcggttcacgggatcctgaacggccaggtagcagccggcaatgtggtcattatccgctac
gaagggcccaagggcggccccggcatgcaggagatgctgtatcccaccagctatctcaag
gcgatggggctgggcaaggagtgtgccctgcttaccgacggccgcttttccggcggtacc
agcggcctctcgatcgggcatgccagtccggaagccgcggccggcggggcaatcgccctg
gtcgaggacggcgacaccatcgagatcgacatcccggggcgcagtataaacatgcgagtc
agcgacagcgaactggagaagcggcgtgctgcccagctcgcccgcggtgacaaggccttt
accccgcacaaccgtgagcgtcaggtcagcaccgccctgaaggtatacgccagcatggcc
accagtgccgatcagggcgcctaccgccagctgccggagtaa
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