Shigella flexneri 2002017 (serotype Fxv): SFxv_2860
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Entry
SFxv_2860 CDS
T01883
Symbol
purL
Name
(GenBank) Phosphoribosylformyl-glycineamide synthetase, FGAM synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sfe
Shigella flexneri 2002017 (serotype Fxv)
Pathway
sfe00230
Purine metabolism
sfe01100
Metabolic pathways
sfe01110
Biosynthesis of secondary metabolites
Module
sfe_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sfe00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SFxv_2860 (purL)
Enzymes [BR:
sfe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SFxv_2860 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
ADA74941
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Position
complement(2714223..2718266)
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AA seq
1347 aa
AA seq
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MATYYSHWRHALLIHDGDFISTQTVSSAHQILYNDARFPPLGYTESLEDERLMMEILRGS
PALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKYGPALASH
APQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTNEQWQQVT
AELHDRMMETVFFDLDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLALAEDEID
YLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFRMIKNTFETT
PDHVLSAYKDNAAVMEGSEVGRYFADHETGRYNFHQEPAHILMKVETHNHPTAISPWPGA
ATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTE
GPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKG
EINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRC
WQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQ
ERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGK
TPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQ
MVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQI
GDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEG
NEEREMTSPLSLVISAFARVEDVRHTITPQLCTEDNALLLIDLGKGNNALGATALAQVYR
QLGDKPADVRDVVQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDAD
IASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITA
NGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINED
VAAPYIATGARPKVAVLREQGVNSHVEMAAAFQRGGFDAIDVHMSDLLTGRTGLEDFHAL
VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRELI
PGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDAAH
LAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTV
SNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
4044 nt
NT seq
+upstream
nt +downstream
nt
atggcaacttattacagccattggcggcacgcgttgctaattcacgatggtgattttatt
tccacgcaaacggtttcgtcagcgcatcagattctttataatgacgcccgtttccccccc
cttgggtacaccgaaagcttagaagacgagagacttatgatggaaattctgcgtggttcg
cctgcactgtcggcattccgaatcaacaaactgctggcacgttttcaggctgccaggctc
ccggttcacaatatttacgccgagtatgtccattttgctgacctcaatgcgccgttaaac
gatgatgagcacgcacaacttgaacgcctgctgaaatatggtccggcactcgccagccac
gccccgcaaggcaaactcctgctggtgaccccgcgtcctggcaccatctctccctggtct
tcgaaagcgaccgatattgcccataactgcgggctacaacaggtaaaccgccttgagcgc
ggcgttgcttactatatagaagccggtacgctgaccaatgaacaatggcagcaggttacc
gctgaactgcacgaccgcatgatggaaacggtcttttttgatttagatgatgcagagcag
ttgtttgcccaccatcaaccgactccggtcacaagcgttgatttgctggggcagggccgt
caggcgctgatcgacgctaacctgcgtcttggcttggctctggcggaagatgaaattgac
tatctgcaggatgctttcacaaagcttggtcgtaacccgaacgacatcgagctgtatatg
ttcgctcaggcgaactctgagcactgccgccacaaaatttttaacgccgactggattatc
gacggtgaacaacagccgaaatcgctgttcaggatgatcaaaaatactttcgaaaccacg
ccagatcacgttctctctgcttataaagataacgccgccgtaatggaaggttctgaagtg
ggccgctactttgctgaccacgaaacgggccgctacaatttccatcaggaaccggcgcac
atcctgatgaaagtcgaaactcacaaccacccgacggcgatttctccgtggccgggcgcg
gcgaccggttccggcggtgaaatccgcgatgaaggtgccaccgggcgcggcgcgaagccg
aaagctggtttggttggtttctccgtatccaacctgcgaattcctggcttcgaacagccg
tgggaagaagatttcggtaagcctgagcgcattgttaccgcgctggacatcatgaccgaa
ggcccgctgggcggtgcggcgtttaacaacgaatttggtcgtccggcactgaacggctac
ttccgtacttatgaagaaaaagtgaacagccacaatggcgaagagctgcgcggttatcac
aaaccgatcatgctggcgggcgggatcggcaacattcgcgccgatcacgtacaaaaaggc
gagatcaacgtcggtgcgaagctggtcgttctcggcggcccggcaatgaacatcggtctt
ggcggcggcgcggcgtcttccatggcgtctggtcagtctgatgccgacctcgactttgct
tccgtacagcgcgacaacccggagatggagcgtcgttgccaggaagtgatcgaccgttgc
tggcagcttggtgatgctaacccaattctgtttatccacgacgtcggtgcgggcggtctt
tctaacgcgatgccggagctggtgagcgacggcggacgcggcggtaaatttgaactgcgc
gatattctaagcgacgaaccgggcatgagcccgctggaaatctggtgtaacgaatcccag
gaacgctacgtgctggcggttgctgccgatcaattaccgctgtttgacgaactgtgtaag
cgtgagcgcgcaccctacgcggtgattggtgaagcgaccgaagaactgcatctttctctg
cacgatcgtcattttgataatcagccgatcgatctgccgctggacgtcctgcttggtaaa
acgccgaagatgacccgcgatgtacaaacgctgaaagcgaagggcgatgcgctggtccgt
gaagggatcaccattgcagacgcggtgaaacgcgtactgcatctgccgaccgtggcggag
aaaactttcctggtgaccatcggtgaccgcagcgtaaccggcatggtggcgcgcgatcag
atggtggggccgtggcaggtgccggtcgctaactgcgcggtcactaccgccagcctcgac
agctactacggtgaagcgatggcgattggcgagcgtgcgccggttgcgctgctggatttc
gccgcctctgcccgtctggcggtcggtgaagcgttaaccaatattgccgcaacacagatt
ggcgatatcaaacgcattaaactttccgccaactggatggcggcggcaggccaccctggt
gaagatgcgggcctgtatgaagccgttaaagccgtgggtgaagaactttgtccggcgctg
ggcctgacgatcccggtgggtaaagactctatgtcgatgaaaacccgctggcaggaaggt
aacgaagagcgcgaaatgacgtcgccgctgtcgctggtgatttctgcatttgcccgcgtg
gaagatgtacgtcacaccatcacgccgcagctttgtaccgaagataacgcactgctgctg
attgatttgggcaaaggcaataacgcgctgggcgcaacggcgctggcgcaggtttatcgt
cagcttggcgacaaaccggcagatgtacgcgatgttgtccaactgaaaggcttctatgac
gcgattcaggcgctggttgcacagcgtaagctgctggcgtatcacgaccgctctgatgga
ggcctgctggtaacgctggcggaaatggcctttgcaggtcattgtggcattgacgcggat
atcgcctctctgggtgacgatcgcctggcggcgttgtttaacgaagaactgggtgcggtg
attcaggttcgtgccgctgaccgtgaagcggtcgagtccgtactggcacagcatgggctt
gcggattgcgtccattatgttgggcaggcggtttccggtgaccgttttgtgattaccgcc
aacgggcagactgtattcagcgaaagccgcactacgttgcgtgtctggtgggcagaaact
acctggcagatgcagcgcctgcgtgacaacccggagtgtgccgatcaggagcatcaggcg
aaatctaacgacgccgatccgggcctgaatgtaaaactgtcgttcgatatcaacgaagat
gtggcagcaccgtatattgccactggcgcacgtccgaaagttgccgtactgcgtgagcag
ggcgtgaactcgcatgttgaaatggcggcagctttccaacgtgggggctttgatgctatc
gacgtgcatatgagcgacctgctgactggacgtacgggactggaggattttcacgccctg
gtcgcgtgcggaggtttctcctacggtgatgtgctgggtgccggtgaaggttgggcgaag
tctatcctgttcaatgaccgtgtacgcgatgagtttgcaaccttcttccatcgtccgcaa
acgctggccctgggggtatgtaacggttgccagatgatgtctaacctgcgtgaactgatc
ccggggagtgagttgtggccacgttttgtgcgtaacacctccgatcgctttgaagcgcgt
ttcagcctggttgaagtaacccaaagcccgtctctgctgttgcaggggatggtgggctcg
caaatgccgattgctgtctctcatggtgaagggcgcgtggaagtgcgtgatgcggcgcat
ctggcggcactggaaagcaaagggctggtggcactgcgctatgtcgataacttcggcaaa
gtcactgaaacctacccggctaacccgaacggttcaccgaacggtattacggcggttacg
actgaaagtggtcgagtcaccattatgatgccgcacccggaacgtgttttccgtactgtc
agcaactcctggcatccggaaaactggggcgaggatggcccatggatgcgcattttccgc
aatgcgcgtaagcagttggggtaa
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