Streptomyces ferrugineus: IM697_00775
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Entry
IM697_00775 CDS
T07428
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00280
Valine, leucine and isoleucine degradation
sfeu00640
Propanoate metabolism
sfeu00785
Lipoic acid metabolism
sfeu01100
Metabolic pathways
sfeu01110
Biosynthesis of secondary metabolites
sfeu01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
IM697_00775 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
IM697_00775 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IM697_00775 (pdhA)
Enzymes [BR:
sfeu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
IM697_00775 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QOV37042
UniProt:
A0A7M2SL89
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Position
complement(167253..168434)
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AA seq
393 aa
AA seq
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MTVESTAARKPRRSAGTKSTAGKTTTARKSQGADPELVQLLTPEGKRVKNAEYDKYVAGI
TPEELRGLYRDMVLTRRFDAEATSLQRQGELGLWASLLGQEAAQIGSGRATREDDYVFPT
YREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNSNNFQLYTIVIGSQTLHATGYAMGITKD
GADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQR
AQGFGFPGVRVDGNDVLACLAVTKWALERARGGEGPTLVEAYTYRMGAHTTSDDPTRYRG
DEERQAWEAKDPILRLRRHLEASNHADEGFFAELEAESEALGKRVREAVRAMPDPDHFAI
FENVYADGHALVDEERARFAAYQASFSDVEGGN
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgaaagccgcgacgcagcgccggtaccaagagcacg
gccggcaagaccacaaccgcaaggaaatcgcagggcgccgaccccgagctcgtgcagctg
ctgacgcccgagggcaagcgcgtcaagaacgccgagtacgacaagtacgtcgccggcatc
acccccgaagagctccgcggcctctaccgcgacatggtgctcacccgacgcttcgacgcc
gaggccacctccctgcagcgccagggcgagctgggcctgtgggcgtcgctgctcggccag
gaggccgcccagatcggctccggccgggccacccgcgaggacgactacgtcttcccgacc
taccgtgagcacggcgtcgcctggtgtcgcggggtcgacccgacgaacctgctcggcatg
ttccgcggcgtgaacaacggcggctgggatcccaacagcaacaacttccagctctacacg
atcgtcatcggctcccagacgctgcacgccacgggctacgcgatgggcatcaccaaggac
ggcgccgacagcgcggtcatcgcctacttcggcgacggcgcgagcagccagggcgacgtg
gccgagtccttcaccttctccgcggtctacaacgcccccgtggtgttcttctgccagaac
aaccagtgggcgatctccgagccgaccgagaagcagacccgtgtgccgctctaccagcgc
gcccagggcttcggcttccccggcgtccgcgtcgacggcaacgacgtcctggcctgcctc
gccgtgacgaagtgggcgctggagcgcgcccgcggcggcgaggggccgacgctggtcgag
gcgtacacgtaccgcatgggcgcccacaccacctccgacgaccccacccgctaccggggg
gatgaggagcgccaggcctgggaggcgaaggacccgatcctgcgccttcgccgccacctc
gaggcctcaaatcacgcggacgagggattcttcgcggaactggaggccgagagcgaggcg
ttgggcaagcgagtgcgcgaggcggtccgcgccatgccggacccggaccacttcgcgatc
ttcgagaacgtgtacgcggacgggcatgcgctcgtcgacgaggagcgcgcccggttcgcc
gcctaccaggcgtcgttctcggacgtagaggggggtaactga
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