Streptomyces ferrugineus: IM697_08105
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Entry
IM697_08105 CDS
T07428
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00790
Folate biosynthesis
sfeu01100
Metabolic pathways
sfeu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
IM697_08105
Enzymes [BR:
sfeu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
IM697_08105
6.3.2.17 tetrahydrofolate synthase
IM697_08105
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QOV38334
UniProt:
A0A7M2SQ18
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Position
1768728..1770215
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AA seq
495 aa
AA seq
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MSESDDPFDEIIAAETERDPDLAVIEAGSRTLRTQGGPPSADVPARPEDPEVDKALREVE
AELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSIHITGTNGKTSTARMIEALLGAFEL
RTGRYTSPHVQSITERISLDGAPISAERFIETYQDIKPYIEMVDGQQEYRLSFFEVLTGM
AYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGGTPGEIATEKAG
IVKQDATVIMAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVSRQVAVGGQLVTLRGLGG
EYPEVYLPLHGAHQAHNAAVALAAVEAFFGVGAARAEPLDIDTIRKAFAAVASPGRMEVV
RRSPTVVLDAAHNPAGARAVAEAVGEAFDFSRLIGVVGASGDKNVRELLEAFEPIFAEVV
VTQNSSHRAMDADELAAIAVEVFGDERVQVEPRLPDALEAAITLAEEEGEFAGGGVLVTG
SVITVGEARLLLGKG
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagagcgacgaccccttcgacgagatcatcgcggcggaaaccgagcgcgacccc
gacctcgccgtcatcgaggcaggcagccgaaccctgcgcacccagggcggtccgcccagc
gccgacgtgcccgcgcgccccgaggaccccgaggtcgacaaggccctgcgcgaggtcgag
gcggagctggcgacacgctggggcgagaccaagctggagccgtcggtcagccgcatcgcc
gcgctcatggacgtcctcggcgagccgcagcggtcgtacccctcgatccacatcaccggc
accaacggcaagacgtcgaccgcccgcatgatcgaggccctcctcggcgccttcgaactg
cgcaccgggcgctacacctcgccgcatgtgcagtccatcaccgagcggatcagcctcgac
ggcgccccgatctccgcagagcggttcatcgagacgtaccaggacatcaagccgtacatc
gagatggtcgacggacagcaggagtaccgcctgtccttcttcgaggtgctcacgggcatg
gcgtacgcggccttcgcggacgcgcccgtcgacgtcgccgtcgtggaagtgggcatgggc
ggctcctgggacgccaccaacgtcatcgacggtgacgtcgccgtcgtgacgcccatagac
ctcgaccacaccgaccggctcggtgggactcccggcgagatcgccaccgagaaggccggg
atcgtcaagcaggacgccaccgtgatcatggcccagcagccggtggacgccgctcaggtg
ctgctgaagaaggccgtggaggtcgacgccaccgtcgcgcgcgagggcctggagttcggg
gtcgtctcgcgccaggtcgccgtcggcgggcagcttgtcacgctgcgcggactgggcggg
gagtaccccgaggtgtatctgccgctgcacggcgcgcaccaggcgcacaacgccgccgtg
gccctcgccgccgtggaggcgttcttcggcgtcggcgccgctcgggccgagccgctggac
atcgacacgatccgcaaggcgttcgcggccgtcgcctcgccgggccggatggaggtcgta
cggcgctctccgaccgtcgtgctggacgccgcccacaatccggcgggcgcgcgggcggtc
gccgaggcggtcggggaggccttcgacttcagccggctcatcggcgtcgtcggcgcgagt
ggcgacaagaacgtgcgcgagctgctggaagccttcgagccgatcttcgccgaggtcgtc
gtcacgcagaactcctcgcaccgcgccatggacgccgacgaactggccgccatcgccgtc
gaggtgttcggcgacgagcgcgtacaggtcgagccgcggctgcccgacgccctggaggcc
gcgatcacgctggccgaggaggagggcgagttcgcgggcggcggtgtgctggtcaccgga
tccgtcatcacggtcggcgaggcccggctgctgctggggaagggctga
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