Streptomyces ferrugineus: IM697_11450
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Entry
IM697_11450 CDS
T07428
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00300
Lysine biosynthesis
sfeu00550
Peptidoglycan biosynthesis
sfeu01100
Metabolic pathways
sfeu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IM697_11450
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IM697_11450
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IM697_11450
Enzymes [BR:
sfeu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IM697_11450
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
DUF561
Motif
Other DBs
NCBI-ProteinID:
QOV38935
UniProt:
A0A7M2STC3
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All DBs
Position
2513954..2515357
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AA seq
467 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQITGSVVRDSREVEPGSLFVAFVGERVDGHDFAQA
VVAAGAAAVLGSRPVGVPAIVVPDVQKALGALARHVVRRLGATLVALTGSVGKTSTKDLI
AQVLQHRAPTVWTPGSFNNEIGLPLTALSATEDTRFLVLEMGARGVGHIRYLTDLTPPRI
GVVLNVGTAHIGEFGGREQIAQAKGELVEGLPPSEDGGAAILNADDPLVRAMASRTKAKV
LLFGESGEADVRAENVRLTDSGQPSFVLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMSAEEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMAKGRR
TWAVLGKMAELGDEALTEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRTGDVVLVKASRSVGLEQVVLALLEGEVSGR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcagacacacgacata
ccggatccgtccgtccagatcaccggatccgtcgtccgggactcccgagaagtggagccc
ggcagcctcttcgtagccttcgtcggcgagcgcgtggacggccacgacttcgctcaggcc
gtcgtcgcggccggcgcggccgccgtactgggctcgcgccccgtcggcgtgcccgcgatc
gtcgtgccggacgtccagaaggccctcggcgccctcgcccgtcatgtcgtacgccggctc
ggcgcgaccctcgtcgccctgaccggctcggtgggcaagaccagcaccaaggacctgatc
gcccaggtgctccagcacagggcgccgaccgtgtggacgccgggctccttcaacaacgag
atcgggctgccgctcaccgccctcagcgccaccgaggacaccaggttcctggtcctggag
atgggcgcccgcggcgtcggccacatccgctatctcaccgatctgacgcccccgaggatc
ggcgtcgtgctcaacgtcggcaccgcgcacatcggcgagttcggcggccgcgagcagatc
gcgcaggccaagggagagctcgtcgagggcctgcctccgtcggaagacggcggcgccgcg
attctcaacgccgacgatcccctcgtacgggccatggcgtcccgtacgaaggcgaaagtg
ctcctattcggagagtccggcgaagcggacgttcgcgccgagaacgtgcgactcacggac
agcggacagccctccttcgtgcttcacacaccctccgggtgcagtgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcggaagagatcgccaccgcgctctccgaagcgggctccctctcacgctgg
cggatggaggtcaccgagcgcccggacggcgtgaccatcgtcaacgacgcctacaacgcg
aacccagaatccatgcgggccgcgctgcgtgccctggccgccatggccaagggccgccgg
acgtgggcggtgctcggcaagatggccgagctcggtgacgaggcgctgaccgaacacgac
gctgtcggacggctcgccgtccgtctcaacgtgagcaagctcgtcgcggtcggggacagg
gaagcgtcctggctgcaactgggcgcatacaacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggctgtcgacctgctgcgcagcgagctgcgcacgggagac
gtcgtgctcgtgaaggcttccaggtcggtgggcctggagcaggtcgtgctcgcactgctc
gagggtgaggtctccggccgatga
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