Serratia fonticola GS2: AV650_07270
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Entry
AV650_07270 CDS
T04716
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sfg
Serratia fonticola GS2
Pathway
sfg00260
Glycine, serine and threonine metabolism
sfg00261
Monobactam biosynthesis
sfg00270
Cysteine and methionine metabolism
sfg00300
Lysine biosynthesis
sfg01100
Metabolic pathways
sfg01110
Biosynthesis of secondary metabolites
sfg01120
Microbial metabolism in diverse environments
sfg01230
Biosynthesis of amino acids
Module
sfg_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sfg_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sfg_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sfg00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AV650_07270 (thrA)
00270 Cysteine and methionine metabolism
AV650_07270 (thrA)
00300 Lysine biosynthesis
AV650_07270 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AV650_07270 (thrA)
Enzymes [BR:
sfg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AV650_07270 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AV650_07270 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ALX93372
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All DBs
Position
1573241..1575700
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AA seq
819 aa
AA seq
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MRVLKFGGTSVANAERFLRVADIVENNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI
LPTMSDAERIFADLLSGLAKALPGFEYDRLKALVEQEFAQLKQVLHGVALLGQCPDSVNA
AIICRGEKLSIAIMEGVFKAKGYPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIP
SDHIILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYREAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTANPQAPGTLIGGESV
ADDTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQSELQRARRALEDEFYLELKDGVLEPLDVMERLAIISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVDNDSATTGVRVSHQMLFNTDQVIEVFVIGVGGVGGAL
IEQVYRQQPWLKQKHIDLRICGIANSRAMLTNVHGISLESWRDELAEAKEPFNLGRLIRL
VKECHLLNPVIVDCTSSQAVADQYADFLADGFHVVTPNKKANTSSMNYYQQLRTAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELMRFTGILSGSLSFIFGKLDEGMSLSEATLQA
KALGYTEPDPRDDLSGMDVARKLLILAREAGYALELSDIEVESVLPPSFDASGDVENFIA
RLPELDAEFNRRVAAAAAEGKVLRYVGAIEEGRCLVRIDAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgcttaaatttggtggaacctcggtagcgaatgcggaacgttttctgcgcgtt
gccgatatcgtggagaacaatgcacgccaaggacaggtagccacggtattgtccgcaccg
gccaagatcaccaatcatctggtggcgatgattgacaaaacggtagccggccaggatatt
ctgccaaccatgagcgacgccgagcgcatctttgccgacctgctcagcggtttggccaag
gcgttgccaggctttgagtacgatcgcctgaaggcactggtcgagcaggagttcgcgcag
ctcaaacaggtactgcatggtgtggcgttgttggggcagtgcccggatagcgtcaatgcg
gctatcatctgtcggggtgaaaagctttctattgccatcatggaaggcgtcttcaaagcc
aaaggttatccggttactgtgattaacccggtagagaagctgctggctcagggccactat
ctggaatcgaccgtggatattgccgagtccaccctgcgtatcgctgctgcggccattcct
tcagaccatatcatcctgatggcgggctttactgccggtaacgacaaaggcgaactggtc
gtgctggggcgcaacggctccgattattctgccgccgtgctggccgcttgcctgcgagca
gactgttgcgagatctggaccgatgtggacggggtttatacctgcgacccgcgtaccgtg
ccggatgcccgattattgaagtcgatgtcctaccgggaggcgatggagctctcttacttc
ggcgccaaagttctccaccctcgtaccatcaccccgattgcccagttccaaatcccttgc
ctgattaaaaacaccgccaacccgcaagctcccggcaccttgatcggtggagaaagcgtg
gccgatgatacgccggtaaagggcatcaccaatctgaacaatatggcgatgatcaacgtg
tccggcccaggtatgaaaggcatggtcggcatggcggcccgtgtgtttgccgtgatgtca
cgcgccgggatctcagtggtgttgatcacccagtcctcttccgagtacagcatcagcttc
tgtgtgccgcagagtgagctgcaacgcgctcgtcgtgccctggaagacgaattctacctg
gagttgaaagacggcgtgctggagccgctggacgtgatggaacgcctggcaattatctcg
gtcgttggcgacggtatgcgcaccctgcgtggcatctctgcgcgcttcttctctgctctg
gcgcgcgccaacatcaatatcgtggcgatcgctcaaggttcttccgagcgttcaatttcc
gtggtggtcgataatgattccgccaccactggcgtgcgcgtcagccatcagatgctgttc
aacaccgatcaggtgatcgaagtgtttgtgattggcgtgggtggcgttggcggggcgctc
atcgagcaggtttatcgtcagcaaccttggctgaagcaaaaacacatcgatctgcgcatc
tgtggcattgccaactcaagggcgatgttgaccaacgtgcacggcatctcgctggaaagc
tggcgggacgaactggccgaagccaaagagcctttcaatctgggccgcctgatccgcctg
gtgaaagagtgccacctgctcaatccggtgattgtcgactgtacctccagccaggcggtg
gccgatcagtatgccgatttcctggccgatggtttccacgtggtaacgccaaacaagaag
gccaacacctcgtcgatgaattattaccagcaactgcgcaccgcagcagccggttctcgc
cgcaaattcctgtatgacactaacgtgggggcgggcttgccggtgatcgaaaacctgcag
aacctgctcaatgcgggcgatgagctgatgcgcttcaccggtatcctgtcggggtcactg
tcctttatcttcggtaagctggatgaggggatgtcgctgtcggaggccaccttgcaggcc
aaggccttgggttacaccgagccagatccgcgtgacgatctttcggggatggatgtcgct
cgcaagctgctgatcctggcgcgtgaagcaggctatgcgcttgaactgagcgatattgaa
gtcgaatcggtgttaccaccgtcgtttgatgccagcggcgatgtggagaactttattgcc
cgcctgccggagttggatgccgaatttaaccgccgtgtggccgctgctgccgcggaaggt
aaggtgctgcgctatgtgggggctatcgaagaaggccgctgcctggtacgtattgatgcg
gtagatggcaacgatccgttgtataaagtgaagaacggtgagaacgctttggccttctac
agccgctactatcagccattgccgctggtgctgcgcggttatggtgccggtaatgatgtg
acggcggccggggtatttgccgatctgttgcgcacactgtcatggaagttgggagtctaa
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