Streptomyces microflavus: SFUL_2183
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Entry
SFUL_2183 CDS
T02650
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfi
Streptomyces microflavus
Pathway
sfi00790
Folate biosynthesis
sfi01100
Metabolic pathways
sfi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SFUL_2183
Enzymes [BR:
sfi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SFUL_2183
6.3.2.17 tetrahydrofolate synthase
SFUL_2183
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGK77140
UniProt:
N0CND9
LinkDB
All DBs
Position
complement(2452088..2453620)
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AA seq
510 aa
AA seq
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MSEPRPSDRHDASQPDDTFEEIVGEETQRDPDLAVIEAGSRTLRTYAGSPQGEAVPARPT
DPETDKALRAVEQELAGRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTA
RMIEALLNAFELRTGRYTSPHVQSITERISLDGSPIEPERFIETYEDIKPYVEMVDAQQP
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDSTVAVVTPISLDHTDRLG
TTPAEIAGEKAGVIKQGATVILAQQPVDAAQVMLKKAVEVDATVAREGMEFGIVSREVAV
GGQLLTLRGLGGAATEYTDIFLPLYGAHQAHNAAVALAAVEAFFGIGAEQARSLDIDAIR
KAFAAVVSPGRLEVVRSSPTVVLDAAHNPAGAKAAADGISEAFSFSRLIGVVGTSGDKDV
RGLLEAFEPIFAEVVVTQNSTERAMDADELAAIAVEVFGDDRVQVEPRLDDALEAAITLA
EEDDEYAGAGVLVTGSVITVGEARLLLGRG
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgcccttcagaccggcacgacgcgtcccagcccgacgacaccttcgag
gagatcgtcggcgaagagacccagcgcgaccccgacctggcggtgatcgaagccgggagc
cgcaccctgcgcacctatgcgggttccccccagggcgaagcggtccccgcccgacccacc
gaccccgagaccgacaaggcgctgcgcgcggtggagcaggagctcgccggacgctggggc
gagaccaagctcgagccctccgtcacccgcatcgccgccctgatggacgtgctcggcgag
ccgcagcgcgcctacccctcgatccacatcacggggaccaacggcaagacctccacggcc
cgcatgatcgaggccctgctcaacgcgttcgagctgcgcaccggccgctacacctcgccg
cacgtccagtcgatcaccgagcggatcagcctcgacggctccccgatcgagcccgagcgc
ttcatcgagacgtacgaggacatcaagccgtacgtcgagatggtcgacgcccagcagccc
taccggctctccttcttcgaggtgctcaccggcatggcgtacgcggccttcgccgacgcg
cccgtcgatgtggcggtcgtcgaggtcggcatgggcggcacctgggacgccaccaacgtc
atcgactccaccgtcgccgtcgtcaccccgatctcgctggaccacaccgaccgcctcggc
accacaccggccgagatcgccggggagaaggcgggcgtcatcaagcagggcgccacggtc
atcctggcgcagcagccggtggacgccgcgcaggtgatgctgaagaaggccgtcgaggtc
gacgccaccgtggcccgcgagggcatggagttcggcatcgtctcccgggaggtcgcggtc
ggcgggcagctgctgacgctgcgcggcctgggtggcgcggccaccgagtacaccgacatc
ttcctcccgctgtacggggcccaccaggcgcacaacgccgcggtggcgctcgccgccgtc
gaggcgttcttcggtatcggcgccgagcaggcccgctcgctcgacatcgacgcgatccgc
aaggcgttcgccgctgtcgtctcgcccggccggctggaggtcgtgcgctccagcccgacc
gtcgtcctggacgccgcccacaacccggcgggcgccaaggccgcggcggacggcatctcc
gaggcgttcagcttctcccggctgatcggcgtggtcggcaccagcggcgacaaggacgtc
cgtgggctcctggaagccttcgagccgatcttcgccgaggtcgtcgtcacgcagaactcc
accgaacgcgcgatggacgcggacgagctggccgccatcgccgtcgaggtcttcggcgac
gaccgggtccaggtcgaaccgcgactcgacgacgcgctggaggcggcgatcacgctggcc
gaggaggacgacgagtacgcgggcgccggagtcctggtgaccggatcggtgatcacggtc
ggcgaggcccggctgctgctgggaaggggctga
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