Streptomyces microflavus: SFUL_3475
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Entry
SFUL_3475 CDS
T02650
Name
(GenBank) Branched-chain alpha-keto acid dehydrogenase E1-alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sfi
Streptomyces microflavus
Pathway
sfi00280
Valine, leucine and isoleucine degradation
sfi00640
Propanoate metabolism
sfi00785
Lipoic acid metabolism
sfi01100
Metabolic pathways
sfi01110
Biosynthesis of secondary metabolites
sfi01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sfi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SFUL_3475
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SFUL_3475
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SFUL_3475
Enzymes [BR:
sfi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
SFUL_3475
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
HupE_UreJ
Motif
Other DBs
NCBI-ProteinID:
AGK78404
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All DBs
Position
complement(3945519..3946679)
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AA seq
386 aa
AA seq
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MTVESTAAARKPRRASKRTSAAKTPQSSEPQLVQLLTPEGERVEHPDYSIDLSADELRGL
YRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAW
CRGVDPTNLLGMFRGVNHGGWDPTTNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVVA
YFGDGASSQGDVAEAFTFSAVYNAPVVFFCQNNQWAISEPTERQTRVPLYQRAQGYGFPG
VRVDGNDVLACLAVTRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADDERAAWE
AKDPILRLRTYLEKEKLADEAFFTELETESETLGKRVREVVRAMPDPEPISLFEHGYADG
NSLVDEERAQFAAYQASFADSAEEGK
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgccgcgcgtaaaccgcgacgcgccagtaagcggaccagc
gccgcgaagacgccacagagttccgagccccagctcgtgcagctgctgacgcccgagggc
gagcgtgtcgagcacccggactacagcatcgacctgagcgcggacgagctgcgcggtctg
taccgggacatggttctgacccgccgcttcgacgccgaggcgaccgcactgcagcgccag
ggggagctgggcctgtgggcctcgctgctcggccaggaggccgcgcagatcggcagcggc
cgggcgctgcgcgacgacgactacgtcttcccgacctaccgcgagcacggcgtggcctgg
tgccgcggggtcgaccccaccaacctgctgggcatgttccgcggggtgaaccacggtggc
tgggacccgacgaccaacaacttccacctgtacacgatcgtcatcggctcgcagaccctg
cacgccaccggctacgccatgggcgtcgccaaggacggcgcggactcggccgtggtcgcg
tacttcggtgacggcgcctccagccagggcgacgtggccgaggcgttcaccttctccgcg
gtctacaacgccccggtcgtgttcttctgccagaacaaccagtgggccatctccgagccc
accgagcgccagacccgcgtgccgctctaccagcgcgcgcagggttacggcttccccggc
gtccgggtcgacggcaacgacgtactcgcctgtctggccgtgacccgctccgcgctggag
cgcgcccgccgcggcgagggcccgaccctggtcgaggcgttcacgtaccgcatgggcgcc
cacaccacctccgacgacccgacgaagtaccgggccgacgacgagcgggccgcgtgggag
gccaaggacccgatcctgcggctgcgcacgtatctggagaaggagaagctcgccgacgag
gcgttcttcaccgagctggagacggagagcgagaccctcggcaagcgcgtacgcgaggtg
gtgcgggcgatgcccgacccggagccgatctccttgttcgagcacggctacgccgacggc
aactccctcgtcgacgaggagcgtgcccagttcgccgcctaccaggcatcgttcgcagac
tccgccgaggagggcaagtag
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