Streptomyces ficellus: EIZ62_24685
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Entry
EIZ62_24685 CDS
T06929
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfic
Streptomyces ficellus
Pathway
sfic00300
Lysine biosynthesis
sfic00550
Peptidoglycan biosynthesis
sfic01100
Metabolic pathways
sfic01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfic00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EIZ62_24685 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EIZ62_24685 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EIZ62_24685 (murF)
Enzymes [BR:
sfic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EIZ62_24685 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
QGV81079
UniProt:
A0A6I6FP28
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All DBs
Position
5473842..5475269
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AA seq
475 aa
AA seq
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MIALSLAEIADITGGQSHDIPDPAVQVTGSVVIDSRQVGPGSLFAAFAGENVDGHDYAQR
AVDAGAVAVLATRPVGVPAIVVDDVQTALGALARAVVRRLGTTVVALTGSAGKTSTKDLI
AQVLQHKGPTVWTPGSLNNEIGLPLTALRAEKDTEHLVLEMGARGIGHIRYLAELTPPTI
GLVLNVGSAHIGEFGGREQIAQAKGEMVEALPAAEAGGIAVLNADDPLVRAMHTRTHARV
TLFGEADDAAVRAENVRLTETGQPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMSVDEIATALSGAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGKAAQ
AKGGRTWAVLGQMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVHVSDARAAIDLLRSELRPGDVVLVKASRSVGLERIATALLEGTEGEVTGR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgacatcaccggcgggcagtcgcacgacata
ccggatccggccgtccaggtcaccggctccgtcgtcatcgactcccgtcaggtcgggccc
ggctcgctcttcgccgcgttcgccggtgagaacgtcgacggccacgactacgcgcagcgc
gccgtggacgcgggcgcggtggccgtgctggccacccgccccgtcggcgtgcccgccatc
gtcgtcgacgacgttcagacggccctcggcgcactcgcccgcgcggtcgtccgccgcctc
ggcaccacggtcgtcgcgctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccaggtgctccagcacaagggccccacggtctggacgcccggctccctcaacaacgag
atcggcctgcccctcaccgccctgcgcgcggagaaggacaccgagcacctcgtcctggag
atgggggcgcgcggaatcggccacatccgctacctcgccgagctgaccccgccgacgatc
ggcctcgtgctgaacgtgggcagcgcccacatcggcgagttcggcggccgcgagcagatc
gcccaggccaagggcgagatggtggaggccctgccggccgccgaggcgggcggcatcgcc
gtgctgaacgcggacgatcctctcgtacgggccatgcacacccgcacccacgcgcgcgtg
acgctgttcggcgaggccgacgacgccgccgtacgtgccgagaatgtccggctcacagag
accggacagccctctttcaggcttcacacacccaccgggtgcagtgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgtcgacgagatcgccaccgcgctctccggggcgggcaccctctcccgctgg
cgcatggaggtcaccgagcgtccggacggtgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggccatgggcaaggcagcacag
gccaaggggggccggacgtgggcggtgctcggccagatggccgagctgggggacgaggcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcagtcgggggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcgatcgacctgttgcgcagtgag
ctgcgcccgggagacgtcgtgctggtgaaggcatcaaggtcggtcgggctcgagcggatc
gccacggcactgctcgagggcaccgagggcgaggtcaccggccgatga
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