Streptomyces finlayi: F0344_18135
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Entry
F0344_18135 CDS
T09573
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sfiy
Streptomyces finlayi
Pathway
sfiy00280
Valine, leucine and isoleucine degradation
sfiy00640
Propanoate metabolism
sfiy00785
Lipoic acid metabolism
sfiy01100
Metabolic pathways
sfiy01110
Biosynthesis of secondary metabolites
sfiy01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sfiy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
F0344_18135 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
F0344_18135 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F0344_18135 (pdhA)
Enzymes [BR:
sfiy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
F0344_18135 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
QNE76285
UniProt:
A0A7G7BLS0
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Position
3901973..3903133
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AA seq
386 aa
AA seq
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MTVQELPGAAAYRPTPPPAWKPLTDPAPLLPDAEPYRVLGTDAAADADPALLLRLYTELV
RGRRYNAQATALTKQGRLAVYPSSTGQEACEIAAALVLEEQDWLFPSYRDTLAAVARGLD
PVEALTLLRGDRHTGYDPREHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDG
GTSEGDFHEALNFAAVWRAPVVFFVQNNGFAISVPLAKQTAAPSLAHKAIGYGMPGRLVD
GNDAAAVHQVLGEAVSRARRGEGPTLVEAVTYRMEAHTNADDATRYRVDSEVEAWRAHDP
IRLMERELTGRGLLDEGGIVAAKEAADVMAAGLRERMNADPVLDPMSLFTHVYAEQTEQL
REQAARLRVELDAEHDQHDDDPEERR
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
atgacggtccaagagctgcccggcgcggctgcctaccggcccacgccgcccccggcctgg
aagccgctcacagacccggcgccactgctcccggacgcggagccgtaccgcgtgctcggc
acggacgcggcggccgacgcggaccccgctctgctgctgcggctctacaccgagctggtg
cgcggtcgccgctacaacgcgcaggccacggccctgaccaagcagggcaggctcgccgtc
tacccgtcgagcaccgggcaggaggcatgcgagatagcggccgcgctcgtgctggaggag
caggactggctcttccccagttaccgcgacaccctcgcggccgtcgcacgcggactcgac
cccgtcgaggcactgacccttctgcgcggcgaccggcacaccggatacgacccgcgcgag
catcgcatcgccccgctctgcaccccgctcgccacccagctgccgcatgccgtgggtctg
gcccacgccgcgcgcctcaagggcgacgacgtggtcgccctcgcgatggtcggcgacggc
ggtaccagtgagggcgacttccacgaggcgctgaacttcgcggccgtctggcgtgccccg
gtcgtcttcttcgtacagaacaacggcttcgcgatctccgtcccgctggccaagcagacc
gcggcgccctccctggcccacaaggccatcggatacgggatgcccggccggctggtcgac
ggcaacgacgcggccgccgtgcaccaggtgctcggtgaggcggtgtcccgcgcccggcgt
ggtgagggaccgacgctcgtcgaggccgtcacctaccggatggaagcccacacgaacgcc
gacgacgccacgcggtaccgcgtcgacagcgaggtcgaggcatggcgggctcacgacccg
atccggcttatggagcgggagctgaccgggcgcggactgctcgacgagggcggcatcgtg
gcggcgaaggaggcggcggacgtgatggccgccggactgcgggagcggatgaacgccgat
ccggtgctcgatcccatgagcctgttcacgcacgtgtacgcggagcagacggagcagctg
cgcgagcaggcggcgcgcctgcgcgtcgagctggacgccgagcacgaccagcacgacgac
gacccggaggaacggcgatga
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