Streptomyces finlayi: F0344_20590
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Entry
F0344_20590 CDS
T09573
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sfiy
Streptomyces finlayi
Pathway
sfiy00860
Porphyrin metabolism
sfiy01100
Metabolic pathways
sfiy01110
Biosynthesis of secondary metabolites
sfiy01120
Microbial metabolism in diverse environments
sfiy01240
Biosynthesis of cofactors
Module
sfiy_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sfiy_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfiy_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfiy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
F0344_20590
Enzymes [BR:
sfiy01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
F0344_20590
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
F0344_20590
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QNE76703
UniProt:
A0A7G7BMY8
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Position
4423301..4424968
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AA seq
555 aa
AA seq
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MSPTGPAASDFPVLPAGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEPHVLDIVRCHA
RAGVSTPELTVVDVSSTAVGVPVLRDAANLVMEAAKGGRRVVRAISGDPGLDGSGGAEML
ACAAAGVPFEVVPGVANAVGVPAYAGVPLRDAQGADVRFVDARTASDRCWAEVGASDATA
VVSTTLDSVAAAAGELVSAGRKPDTPLTVTIAGTTTRQRTWTATLGTIAQLFKQTKVLPS
PDGHQPVIAVVGERSSAAQREQLAWFESKPMFGWNVLVPRTKEQAASLSDQLRSYGAVPH
EVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIK
VAAVGEQTAAALIDFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATET
LVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGKP
HNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEALAAFGAQRRDAAKEAGDPVTR
PSERRPGARRRRTTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccggccccgccgcatccgattttcctgtcctgcccgcagggcacgtcacc
ttcctcggcgccggtcccggcgacccgggactgctgactctgcgcgccgtcgaggcgctc
gcgagcgcggacgtccttgtcgcggaaccacacgtcctcgacatcgtccgctgccatgcg
cgggcaggcgtaagcacgcctgagctgacggttgttgacgtgtcgtcaacagccgtcggg
gtgcccgttctcagggatgcggccaatcttgtcatggaggccgccaagggcggcaggcgg
gtcgtgcgagccatttcgggtgaccccgggctggacgggtccgggggcgcggagatgctc
gcctgcgccgccgccggcgtgcccttcgaggtcgtgcccggtgtcgccaacgccgtgggc
gtgcccgcgtacgccggcgtgccgctgcgcgacgcgcagggcgccgacgtccgtttcgtc
gacgcgcgtacggcttcggaccgctgctgggccgaggtcggcgcgagcgacgccacggcc
gtggtgtccaccacgctcgactcggtggccgcagccgccggtgagctggtctcggcgggt
cgcaagcccgacaccccgctgaccgtcacgatcgccggtacgacgacccgccagcggacc
tggacggcgacgctcggcacgatcgcgcagctgttcaagcagacgaaggtgctcccgtcg
cccgacgggcaccagcccgtcatagccgtggtcggcgagcgcagctccgccgcccagcgc
gagcagctcgcgtggttcgagtccaagccgatgttcggctggaatgtgctcgtgccgcgc
accaaggagcaggcggcttcgctctccgaccagctgcgttcctacggcgcggtgccgcac
gaggtgccgacgatcgccgtcgagccgccgcgtacgccccagcagatggagcgcgcggtc
aagggcctggtcacgggccgctacgagtggatcgccttcacgtccgtcaacgcggtgaag
gccgtccgggagaagttcgaggagtacgggctcgacgcccgtgccttcgccgggatcaag
gtcgcggccgtcggtgagcagacggccgccgcgctgatcgacttcggggtgaagccggac
ctggtgccgtccggcgagcagtccgccgccgggctgctggaggactggccgccgtacgac
ccggtcttcgacccgatcgaccgtgtcttcctgccgcgtgccgacatcgccaccgagacc
ctggtggccgggctcatcgagctgggctgggaggtcgacgacgtcaccgcgtaccgcacg
gtccgcgcctcgccgccgcccgccgacacgcgtgaggccatcaagggcggcgggttcgac
gcggtgctgttcacctcgtcgtccaccgtgcgcaacctcgtcggtatcgcgggcaagccg
cacaacgtgacggtgatcgcgtgcatcggcccggccacggcgaagaccgccgaggagcac
ggcctgcgggtcgacgtgctgtccccggagccctcggtgcacaagctggccgaggcgctt
gcggcgttcggcgcgcagcgccgggacgcggccaaggaggccggtgacccggtgacccgg
ccgagcgagcggcgtccgggtgcccggaggcgtcgtacgacgacctga
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