Streptomyces finlayi: F0344_24910
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Entry
F0344_24910 CDS
T09573
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfiy
Streptomyces finlayi
Pathway
sfiy00790
Folate biosynthesis
sfiy01100
Metabolic pathways
sfiy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfiy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
F0344_24910
Enzymes [BR:
sfiy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
F0344_24910
6.3.2.17 tetrahydrofolate synthase
F0344_24910
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QNE77402
UniProt:
A0A7G7BPY7
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Position
5395730..5397232
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AA seq
500 aa
AA seq
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MTEQPDPSDNSFDEIVDAETQRDPDLAVIEAGSRTLRTHSGPPEGAEVPTRPTDPETDKA
LRAVERELAGRWGETKLEPSVTRIAALMDVLGDPQRAYPSIHITGTNGKTSTARMIEGLL
NAFDLRTGRYTSPHVQSITERISLDGAPVEAERFIETYEDIKPYVEMVDAQQEIRLSFFE
VLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDATVAVVTPISLDHTDRLGNTPAEIA
GEKAGVIKQDATVILAQQPVDAAQVMLKKAVEVDATVAREGMEFGIVSREIAVGGQFLTL
RGLGGEYDGIFLPLYGAHQARNAAVALAAVEAFFGIGSERSGSLGIEAVRKAFASVVSPG
RLEVMRSSPTVVLDAAHNPAGARAAAEGLTEAFSFSRLIGVVGTSGDKDVRGLLEAFEPI
FAEIVITQNSSGRAMNVDELAAIAVEVFGNDRVQVEPRLDDALEAAITLAEEEDEYAGAG
VLVTGSVITVGEARLLLGRG
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgagcagcccgaccccagcgacaacagcttcgacgagatcgtcgacgccgagacc
cagcgcgaccccgacctggcggtgatcgaggccgggagccgcacactgcgcacccattcg
ggaccgccggagggcgccgaggttcccacccgtcccaccgacccggagaccgacaaggca
ctgcgcgccgtcgagcgggagctcgccggccgctggggcgagaccaagctcgaaccgtcg
gtgacccgcatcgcggcactgatggacgtgctcggtgacccgcagcgcgcgtacccctcc
atccacatcacggggaccaacggcaagacgagcacggcccgcatgatcgagggcctgctg
aacgccttcgacctgcgcaccggccgctacacctcgccgcacgtccagtcgatcaccgag
cggatcagcctggacggcgccccggtcgaggccgagcgcttcatcgagacgtacgaggac
atcaagccgtacgtcgagatggtcgacgcccagcaggagatccggctgtcgttcttcgag
gtgctgacgggcatggcgtacgcggccttcgccgacgcgccggtcgatgtcgcggtcgtc
gaggtcggcatgggcggcacctgggacgcgacgaacgtcatcgacgccacggtcgcggtc
gtcacccccatctcgctggaccacacggaccgcctcggcaacacgcccgcggagatcgcg
ggggagaaggccggcgtcatcaagcaggacgcgacggtcatcctggcgcagcagcccgtg
gacgcagctcaggtgatgctgaagaaggccgtcgaggtggacgccaccgtggcccgcgag
ggcatggagttcggcatcgtctcccgggagatcgcggtcggaggccagttcctgaccctg
cgcggactcggcggcgagtacgacgggatcttcctcccgctgtacggcgcccaccaggcc
cgcaacgcggcggtcgcgctcgccgcggtcgaggccttcttcggcatcggctccgagcgg
agcggctcgctgggcatcgaggcggtccgcaaggcgttcgcctcggtcgtctcgccgggc
cgcctcgaagtcatgcgcagcagcccgaccgtggtcctggacgccgcccacaaccctgcg
ggcgcccgcgccgcagcggaagggctgacggaggcgttcagcttctcgcggctcatcgga
gtggtcggcacgagcggcgacaaggacgtccgggggctgctcgaagccttcgagccgatc
ttcgccgagatcgtcatcacgcagaactccagcggtcgtgcgatgaacgtggacgagctg
gccgcgatcgccgtggaggtcttcggcaacgaccgcgtgcaggtcgagccgcgcctcgac
gacgcgctggaggcggcgatcaccctggccgaggaagaggacgagtacgcgggagcgggc
gtcctcgtgaccggttccgtgatcaccgtcggcgaggcccgactgcttctgggaaggggc
tga
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