Streptomyces finlayi: F0344_27940
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Entry
F0344_27940 CDS
T09573
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfiy
Streptomyces finlayi
Pathway
sfiy00300
Lysine biosynthesis
sfiy00550
Peptidoglycan biosynthesis
sfiy01100
Metabolic pathways
sfiy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfiy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
F0344_27940 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
F0344_27940 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
F0344_27940 (murF)
Enzymes [BR:
sfiy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
F0344_27940 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PGM1_C_vert_fung
Motif
Other DBs
NCBI-ProteinID:
QNE77918
UniProt:
A0A7G7BRF3
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Position
6084346..6085776
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AA seq
476 aa
AA seq
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MITLSLTEIAEIVGGQPHDIPDPAVTVGGPVVIDSREVKPGSLFVALPGEQADGHDFAQR
AVEAGAAAVLAARPVGVPAIVVDDVEAALGALARAVVQRLGATLVALTGSAGKTSTKDLI
AQLLERKAPTVWTLGSFNNELGLPLTALRATEETQHLVLEMGARGIGHIRYLAGITPPRI
GLVLNVGTAHIGEFGSREAIAEAKGELVEALPAAAEGGVAVLNADDHLVRAMAARTKARV
LLFGEAADADVRGENVRLTEDGRPAFELHTPTGCSGVTLRLYGEHHVSNALAAAAVAHEL
GMSVTEIAVALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKASR
AGGGRTWAVLGQMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVALALLENSAEGEVVVR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctttccctcaccgagatcgccgaaatcgtcggcgggcagccgcacgacata
cccgatccggcagtcaccgtcggcgggcccgtcgtcatcgactcccgggaggtgaagccc
ggcagcctgttcgtggccctgccgggcgagcaggccgacggccacgacttcgcgcagcgc
gccgtcgaggcgggcgcggcagcagtgctggccgcccgccccgtcggcgttccggcgatc
gtcgtcgacgacgtcgaggcggcgctcggcgcactcgcccgcgccgtcgtccagcggctc
ggagccaccctcgtcgcgctcacgggatctgcgggcaagacctccaccaaggacctgatc
gcccagctcctggagcgcaaggcccccaccgtctggaccctgggctccttcaacaacgag
ctcggcctgcccctcaccgcgctccgcgccaccgaggagacccagcacctcgtcctcgaa
atgggcgctcgcgggatcggccacatccgctacctggccggcatcacgccaccgcgcatc
ggactggtcctcaacgtcggcaccgcgcacatcggcgagttcggcagccgtgaggcgatc
gccgaggccaagggcgagctcgtggaggcccttccggccgcagcggaaggcggcgtcgcc
gtcctcaacgccgacgatcacctcgtgcgggccatggccgcccgcacaaaagcgcgggtc
ctgctcttcggagaggccgcggatgcggacgtacggggagagaacgtccggctcaccgag
gacgggcgccccgctttcgagctccacacacccaccgggtgcagcggcgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttg
ggcatgtccgtgactgagatcgccgtggcgctctccgaggcgggcaccctctcccgctgg
cgcatggaggtcaccgagcgtccggacggtgtgacggtcgtcaatgacgcctacaacgcg
aaccccgaatccatgagagccgcactccgtgcgctggctgccatgggcaaagcctcacgg
gccggagggggacgcacgtgggcggtgctcggtcagatggccgagctcggtgacgcgtcg
ctcgccgagcacgacgctgtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gctgtcggaggaagagaagcctcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcacaggcggccgtcgacctgttgcgcagtgaa
ctgcgcccgggagacgtcgtgctggtgaaggcgtcccggtcggtcggcctggagaaggtc
gctctggcactgctggagaactctgccgagggcgaggtcgtcgtccgatga
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