Serratia ficaria: SAMEA4384070_0712
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Entry
SAMEA4384070_0712 CDS
T06444
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sfj
Serratia ficaria
Pathway
sfj00260
Glycine, serine and threonine metabolism
sfj00261
Monobactam biosynthesis
sfj00270
Cysteine and methionine metabolism
sfj00300
Lysine biosynthesis
sfj01100
Metabolic pathways
sfj01110
Biosynthesis of secondary metabolites
sfj01120
Microbial metabolism in diverse environments
sfj01230
Biosynthesis of amino acids
Module
sfj_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sfj_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sfj_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sfj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SAMEA4384070_0712 (thrA)
00270 Cysteine and methionine metabolism
SAMEA4384070_0712 (thrA)
00300 Lysine biosynthesis
SAMEA4384070_0712 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SAMEA4384070_0712 (thrA)
Enzymes [BR:
sfj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SAMEA4384070_0712 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SAMEA4384070_0712 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
SNV87773
UniProt:
A0A240AYB4
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All DBs
Position
1:758196..760655
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIEKTVAGQDI
LPNMSDAERIFADLLSGLAQALPGFEYDRLKAAVEQEFAQLKQVLHGVALLGQCPDSVNA
AIICRGEKLSIAIMEGVFLAKGFPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIP
ADHVVLMAGFTAGNDRGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYREAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTANPQAPGTLIGRDSS
DDEMPVKGITNLNNMAMINVSGPGMKGMIGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQGELQRARRALEDEFYLELKDGVLEPLDVMEQLAVISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVSNDSATTGVRVCHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQKHIDLRVCGIANSRAMLTNVHGIALDSWRDELAGAQEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLSDGFHVVTPNKKANTSSMNYYQQLRTAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDEGMSLSAATRQA
KANGYTEPDPRDDLSGMDVARKLLILAREAGYKLELDDIEVESVLPPSFDASGDVESFMA
RLPELDKAFARNVADAAEQGKVLRYVGVIEEGRCQVRIDAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtagcgaatgcggaacgttttctgcgcgtc
gccgacatcatggaaagtaatgcgcgtcagggacaggtggccacggtattgtccgcgccc
gccaagatcaccaaccacctggtggcgatgattgaaaaaacggtggctggacaagacatt
ctgccgaatatgagcgacgccgaacgcatcttcgccgatctgctgagcggcctggcccag
gcgctgcccggctttgaatacgatcgcctgaaggccgccgtcgagcaggaattcgcccag
ctcaagcaggtgctgcacggcgtggcgctgctggggcagtgcccggacagcgtcaacgcc
gcgatcatctgccgcggcgagaagctctccatcgccatcatggaaggcgtgttcctggcc
aagggtttcccggtgacggtgatcaatccggtggagaaactgctggcgcagggccactac
ctggagtccacggtggacatcgccgaatccacgctgcgcatcgccgctgcggcgatcccg
gccgatcacgtcgtgctgatggccggtttcaccgccggcaacgataggggcgagctggtg
gtgctgggccgcaacggctccgactattccgccgcggtgctggccgcctgcctgcgcgcc
gactgctgcgagatctggaccgacgtcgacggcgtttatacctgcgatccgcgcaccgtg
ccggacgccaggctgttgaaatcgatgtcgtaccgggaggcgatggagctttcctacttc
ggcgccaaagttcttcacccccgcaccatcgcccccatcgcccagttccaaatcccttgc
ctgatcaaaaacaccgccaacccgcaggccccgggcacgctgattggccgagacagctcg
gacgacgagatgccggtgaagggcatcaccaacctgaacaacatggcgatgatcaacgtc
tccggcccgggcatgaagggcatgatcggcatggccgcccgggtgttcgccgtgatgtcg
cgcgccggcatctcggtggtgctgatcacccagtcctcttccgaatacagcatcagcttc
tgcgtgccgcagggcgagctgcagcgggcgcgtcgcgcgctggaagacgagttctatctg
gagctgaaagacggggtgctggagccgctggacgtcatggagcagctggcggtcatttcg
gtggtcggcgacggcatgcgcaccctgcgcggcatctccgcccgcttcttctccgcgctg
gcgcgcgccaacatcaatatcgtcgccatcgcccaggggtcttccgagcgttccatctcg
gtggtggtcagcaatgattccgccaccaccggcgtgcgcgtttgccatcagatgctgttc
aacaccgaccaggtgatcgaagtgttcgtcatcggcgtcggcggcgtcggcggcgcgctg
atcgagcagatctaccgccagcagccgtggctgaagcaaaagcatatcgacctgcgggtg
tgcggcatcgccaactcgcgcgccatgctgaccaacgtgcacggcatcgcgctggacagc
tggcgcgatgagctggccggcgcgcaggagccgttcaacctgggccgcctgatccgcctg
gtgaaggagtaccacctgctgaacccggtgatcgtcgactgcacctccagccaggcggtg
gcggatcagtacgcggacttcctgagcgacggcttccacgtggtgacgccgaacaagaag
gccaacacctcgtcgatgaactattatcagcaactgcgcaccgcggccgccggttcacgc
cgcaagtttttgtatgacaccaacgttggcgccggcctgccggtgatcgaaaacctgcaa
aacctgctgaacgccggcgacgagctgacgcgtttctccggcatcctgtccggttcgctg
tctttcatcttcggcaagctggacgagggcatgtcgctgtcggcggccacccggcaggcc
aaggccaacggctacaccgagccggacccgcgcgacgacctgtccggcatggacgtggcc
cgcaagctgttgatcctggcgcgcgaagccggttacaagctggagctggatgacatcgag
gtcgaatcggtgctgccgccgtccttcgacgcgtccggcgacgtggaatcctttatggcg
cggctgcccgagctggacaaggcgtttgcgcgcaacgtggccgacgccgccgaacagggc
aaggtgctgcgctacgtcggggtgattgaagaggggcgctgccaggtacgcattgatgcg
gtagacggcaacgatccgttgtataaagtgaagaacggcgagaacgcgctggccttctac
agccgctattatcagccgctgccgctggtgttgcgcggctacggcgcgggtaacgatgtg
actgcggcgggggtcttcgccgacctgctgcgcacactgtcatggaagttgggagtttaa
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