Streptomyces formicae: KY5_2728c
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Entry
KY5_2728c CDS
T05416
Name
(GenBank) Dihydrofolate synthase, Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sfk
Streptomyces formicae
Pathway
sfk00790
Folate biosynthesis
sfk01100
Metabolic pathways
sfk01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KY5_2728c
Enzymes [BR:
sfk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
KY5_2728c
6.3.2.17 tetrahydrofolate synthase
KY5_2728c
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ATL27746
UniProt:
A0A291Q898
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Position
complement(3213411..3214973)
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AA seq
520 aa
AA seq
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MSVPLRRLAYVSDLPPRDDDRDPTDPTDSDDAFEGIVDAETDRDPDLAVIEAGSRTLRTQ
AGPPQGDIPARPTDPEVDRALREVETELAGRWGETKLEPSVSRIAALMDVLGEPQRAYPS
IHITGTNGKTSTARMIEALFAAFDLRTGRYTSPHVQSITERISLDGAPIEAERFVETYHD
IKPYVEMVDSQQEYRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGSVAV
VTPIDLDHTDRLGSTPGEIATEKSGIIKPDATVIMAQQPVDAAQVLLKKAVEVDATVARE
GLEFGVVARQVAVGGQLLTLRGLGGEYEEIFLPLHGEHQAHNAAVALAAVEAFFGIGSQH
ARPLDIENIRKAFATVTSPGRLEVVRRSPTIVLDAAHNPAGARATAAAISEVFDFSNLIG
VVGASEGKDMKGLLEAFEPIFAEIVVTQNTSHRAMDADTLAALAVEVFGDDRVQVEPRLP
DALEAAITLAEEEGEYAGGGVLVTGSVITVGEARLLLGRG
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgtcggtgccgctccgtagactggcgtacgtgagtgacctccccccgcgcgacgacgac
cgcgacccgaccgaccccaccgactccgacgacgccttcgagggcatcgtcgacgccgag
accgaccgggaccccgacctcgccgtgatcgaggcgggcagccgcaccctgcgcacccag
gcgggcccgccgcagggagacatccccgcgcgccccaccgatccggaggtggacagggcg
ctgcgcgaggtcgagacggagctcgcgggccgctggggcgagacgaagctcgagccgtcc
gtcagccgcatcgccgcgctgatggacgtgctcggcgagccccagcgcgcgtacccctcg
atccacatcacggggacgaacggcaagacgtccacggcccgcatgatcgaggccctgttc
gccgccttcgacctgcgcaccgggcgctacacctcgccccacgtccagtcgatcaccgag
cgcatcagcctggacggcgcccccatcgaggccgagcgcttcgtggagacgtaccacgac
atcaagccgtacgtggagatggtcgactcccagcaggagtaccgcctctccttcttcgag
gtgctcacgggcatggcgtacgcggccttcgcggacgcccccgtggacgtcgccgtcgtc
gaggtcggcatgggcggcagctgggacgcgacgaacgtgatcgacggctcggtggccgtc
gtgacccccatcgacctggaccacacggaccgcctgggctccacgcccggcgagatcgcc
accgagaagtccggcatcatcaagccggacgcgacggtgatcatggcccagcagccggtg
gacgccgcgcaggtgctcctgaagaaggccgtcgaggtcgacgcgacggtcgcccgcgag
ggcctggagttcggcgtggtggcccgtcaggtcgccgtcggcggccagctcctgacgctg
cgcggcctcggcggggagtacgaggagatcttcctgccgctgcacggcgagcaccaggcg
cacaacgcggcggtggccctcgccgcggtcgaggcgttcttcggcatcggctcgcagcac
gcgcgcccgctggacatcgagaacatccgcaaggcgttcgccacggtgacgtcgccgggc
cgcctcgaggtcgtgcgccgctcgccgaccatcgtcctcgacgccgcgcacaaccccgcg
ggcgcccgcgccaccgccgccgcgatcagcgaggtcttcgacttcagcaacctgatcggc
gtggtcggcgcgagcgagggcaaggacatgaaggggctgctcgaagccttcgagccgatc
ttcgccgagatcgtcgtcacgcagaacaccagccaccgcgcgatggacgcggacacgctg
gccgcgctcgccgtcgaggtcttcggcgacgaccgcgtccaggtcgagccgcgcctgccg
gacgccctggaggcggcgatcaccctcgccgaggaagagggcgagtacgcgggcggcggc
gtcctggtcaccggctccgtcatcacggtcggcgaggcccggctgctcctgggaaggggc
tga
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