Shigella flexneri 301 (serotype 2a): SF0083
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Entry
SF0083 CDS
T00097
Symbol
murF
Name
(RefSeq) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfl
Shigella flexneri 301 (serotype 2a)
Pathway
sfl00300
Lysine biosynthesis
sfl00550
Peptidoglycan biosynthesis
sfl01100
Metabolic pathways
sfl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SF0083 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SF0083 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SF0083 (murF)
Enzymes [BR:
sfl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SF0083 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Peptidase_S28
Motif
Other DBs
NCBI-GeneID:
1024563
NCBI-ProteinID:
NP_706041
UniProt:
A0A0H2VSH0
A0AB36P876
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All DBs
Position
93268..94626
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AA seq
452 aa
AA seq
DB search
MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPALVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGMEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSMGKQSHAISTASGVGEHFADKTALITRLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatatcacccttgatgctgtaaccactgatacccgaaaactgacgccgggctgcctgttt
gttgccctgaaaggtgaacgttttgatgcccacgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggacatcgacctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
ctcgtggttgctctgacggggtcctccggcaaaacctccgttaaagagatgacggcggcg
attttaagccagtgcggcaacacgctttatacggcaggcaatctcaacaacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgagattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaatatccatgtgacctcgcacggtatg
gaatttaccctacaaaccccaaccggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttcctggccgtctgttccccatc
caactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgcagctgttcaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggtgaggcggcaaaa
gctgctggtattgaccgcgtgttaagcatgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacattttgctgataaaactgcgttaattacgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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