Sphingorhabdus sp. SMR4y: SPHFLASMR4Y_00085
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Entry
SPHFLASMR4Y_00085 CDS
T04949
Symbol
murC
Name
(GenBank) UDP-N-acetylmuramate--L-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfla
Sphingorhabdus sp. SMR4y
Pathway
sfla00300
Lysine biosynthesis
sfla00550
Peptidoglycan biosynthesis
sfla01100
Metabolic pathways
sfla01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfla00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPHFLASMR4Y_00085 (murC)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPHFLASMR4Y_00085 (murC)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPHFLASMR4Y_00085 (murC)
Enzymes [BR:
sfla01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPHFLASMR4Y_00085 (murC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4165
Motif
Other DBs
NCBI-ProteinID:
ASK86879
UniProt:
A0A220W244
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Position
99646..101043
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AA seq
465 aa
AA seq
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MSILWTSAAIAEATAGQSSGDFSANGVAFDSREIGPGDLFVALKGEQSDGHLYVEQAFAS
GAAGAIVSQPVDGPHILVSDTARALDALARASRSRTEAKIIGVTGSVGKTGTKEALYAAL
DRCSFGRAHRSVKSYNNHVGVPLSLSRMPEDTRFGIFEMGMNHAHELSALTRLVRPHAAI
ITAIAPAHIGNFSNGELGIVDAKAEIFEGLMPGGTAIIPHDSPHCERLRKKAERHAEHVI
SFGFDAGADVRAIDIVAAPRGGSLVTAKLGDQSLCFTIAEAGRHWVSNSLAILAAVRAVG
GDLATAGLALAEMSGIDGRGRRHVVSLKSGGTATLIDESYNANPASMKATLQHFATEPCT
GQKIAILGAMGELGAQSAHYHAALADDILRSGAQAIILVGEDMAHTAAKLEQGLDRGVKM
SHAASASDALAEVAKLLSDGDILLVKGSNYLGLSSAVSALASGEY
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgagcatattgtggacatccgccgcgatagcggaagcgacagccggtcagtcgagcggc
gatttttccgcgaacggcgtcgcttttgactcgcgtgaaatcggtccgggcgatctgttc
gtcgcgctcaagggcgagcagagcgacggtcatctgtacgtggaacaggcctttgcctcc
ggcgctgccggcgccatcgtcagccagccggtcgacgggccccatattctggtatctgac
accgccagggcgctcgatgcgctggccagagcatcgcgctcccgtaccgaggcgaaaatc
atcggtgtgaccggctcggtcggcaagaccggtacgaaggaagcattatatgctgcgctc
gaccgctgttccttcggcagggcgcaccgctcggtcaaaagctacaataatcatgtcggt
gtcccgctcagcctctcgcgcatgccggaagacacaagatttggcatctttgaaatgggg
atgaatcacgcgcacgaactgtcggcgctgacccgtctggtgcgaccgcatgctgcgatc
atcaccgcgatcgcaccggcccatatcggcaatttttccaacggcgagctcggtatcgtc
gacgccaaggccgagatattcgagggcctgatgcccggtggcaccgccatcatcccgcat
gacagcccccattgcgaacgactgcggaaaaaggcggagcgccacgccgagcatgtgatc
tccttcggctttgatgccggagccgacgtccgcgcgatagatattgttgcggcgccgcga
ggcgggtcgctggttacggcgaaactcggcgaccagagcctctgcttcacgatcgcggag
gcggggcggcactgggtgtccaattcgctggccatattggcggccgtacgcgcggtcggc
ggtgatctcgcgacggccgggctggcgctcgcggaaatgagcgggatcgacgggcggggc
cgtcgccatgttgtctcgctgaaatccggtggcacggcaaccctcatcgacgaaagctac
aatgccaatccggcatcgatgaaagcgacgttacaacattttgcaactgagccctgcacc
ggacaaaagatcgccatattgggcgcgatgggcgagctgggcgcgcaatcggcgcattat
cacgcggccttggcagacgatattctgcggtccggcgcccaggccatcatcttggttggc
gaggatatggcacatactgccgcgaaactcgaacagggccttgatcggggcgtgaaaatg
tcacatgcggcaagtgcttcggacgcgctggccgaggtcgcaaaattgctcagcgacggg
gatatccttctggtcaagggttcaaattatctggggctttcctccgcggtttccgcgctg
gcaagcggggagtattga
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