Scleropages formosus (Asian bonytongue): 108939633 Help Entry 108939633         CDS       T04919                                  Symbol ryr2 Name (RefSeq) ryanodine receptor 2 isoform X1   KO K04962   ryanodine receptor 2 Organism sfm  Scleropages formosus (Asian bonytongue) Pathway sfm04020   Calcium signaling pathway sfm04260   Cardiac muscle contraction sfm04261   Adrenergic signaling in cardiomyocytes sfm04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sfm00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     108939633 (ryr2)    04020 Calcium signaling pathway     108939633 (ryr2)  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     108939633 (ryr2)    04261 Adrenergic signaling in cardiomyocytes     108939633 (ryr2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sfm04040]     108939633 (ryr2)    04990 Domain-containing proteins not elsewhere classified [BR:sfm04990]     108939633 (ryr2) Ion channels [BR:sfm04040]  Voltage-gated cation channels   Ryanodine receptor    108939633 (ryr2) Domain-containing proteins not elsewhere classified [BR:sfm04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    108939633 (ryr2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  108939633 NCBI-ProteinID:  XP_029104698 LinkDB All DBs Position 24:16443797..16582522 Genome browser AA seq 4962 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCSATINKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP DLSICTFVLEQSLSVRALQEMLANTEEKAEGKFMMKTAQGGGHRTLLYGHAVLLRHSYSG MYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSVS SERYLHLSYGNGSLHVDAAFQQTLWSVAPICSGSEVAQGYLIGGDVLRLLHGHMDECLTV PSGDHGEEQRRTVHYEGGAVSIHARSLWRLETLRVAWSGSHTRWGQPFRLRHVTTGKYLS LTDDRGLLLMDKEKADVKSTAFCFRSSKEKLDLGVKKEVDGMGVAEIKYGDSVCYVQHVD TCLWLTYQAVDAKCARMGGVQRKAIMHHEGHMDDGLTLSRSQHEESRTARVIRSTVFLFN RFIRGLDALSKKGKISTLDLPIESVSLSLQDLIGYFQPPDEHLEHEDKQNRLRALKNRQN LFQEEGMINLVLECIDRLHVYSSAAHFADVAGKEAGVAWKSILNSLYELLAALIRGNRKN CAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGRN HKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSVRPNIFLGISEGS AQYRKWYYELIVDHVEPFVTAEATHLRVGWATTDGYSPYPGGGEGWGGNGVGDDLYSYGF DGLHLWSGCIARTVNSPNQHLLRVDDVVSCCLDLGAPSISFRINGQPVQGMFENFNADGL FFPVVSFSTGVKVRFLLGGRHGEFKFLPPPGYAPCFEAVLPREKLRVEHSQEYKQDHSGT RDLLGPIITLTQAAFTPTPVDTSQIVLPPHLEQIREKLAENIHELWVMNKIELGWTYGTV RDDNKRQHPCLVEFSKLPEQERSYNLQMSLETLKTLLALGCHVGVADEHTEERVKRLKLS ANYELSSGYKPAPMDLSHIKLSSTQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVKNR RNPRLVPYALLDERTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARSDISNMLAERFRI FRAEKTYSVNAGKWYFEFEVVTAGEMRVGWARPGCLPDQELGSDDQAFVFDGFKAQRWHQ GNEHFGRSWQPADVVGCMVDMNERTMMFTLNGEVLLDDSGSELAFKDFEVWEGFIPVCSL GVCQVGRMNFGKDVSTLKYFTICGLQEGFEPFAVNMNRDLTMWFSKRLPQFIPVPQNHEH IEVTRIDGTIESSPCLKVTQRSFGSQNSNRDIVFYRLSMPIECAEGFSKSLCGIPSNGSF FSPKKELDDFETVSDFEVLMKTAHGHLSSNGPEKDKDEFNNHKDYNQEKPSKLKQRFMLK RTKPDLSTSHSSPRLSEEVLADERDDYEYLMQTSMYYYSVRIFPGQEPSSVWVGWVTSDF HQYDTAFDLEKVRTVTVTLGDEKGKVHESIKRSNCYMVWAGESTSPGQSRNSNGLEIGCL VDTSHGLLTFTSNGKELSTYYQVEPSTKLFPAVFAQATSPSVFQFELGRIKNVMPLSAGL FKSERKNAIPQCPPRLHVQFLTPVLWSRVPNHFLEVEASRINDRHGWLVQCSKPLQFMSL HIPEENRSVDILELTEQKDLLKFHYHTLRLYSAVCALGNNRVAHALCSHVDEAQLLYAIE NKYMPGLLRTGYYELLIDIHLSTYATARLMMNNEYIVPMTEETKSITLFPDEKKKHGLPG IGLSTSLRPRMRYSSPNFVGVGGDFYQHSPEFPLEVLKSKTIEMLTEAVQEGSLHVRDPV GGSTEFLFVPLIKLFYTLLIMGVFHNGDLKNILQLIEPSVFSEGPGHERAETPDCGGFKA ELQINGVGGEDDGRSGKVPKVGLLQMKLPEPVKLQMCHLLQYLCDCQVRHRIEAVVAFSD DFVANLQENQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFKDEKQDCPCPE DIREQLLDFHEDLMKHCGIEIDDDKTNEADGDFTIRGRLLSLVEKVAYLKKKRADLPKKK KAKKPTTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGQVRALPKTYTINS VSVEDTINLLASLGQIRSLLSVRMGREEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHET VMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLA SPSMRGSTPLDVAAASVMDNNELALALREPDLEKVVQYLAGCGLQSCLMLVSKGYPDIGW NPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAAMEEA IKISEDPSRDGPSPTSESSRTLSDMLEDEEDDTIHMGNAIMTFYAALIDLLGRCAPEMHL IHAGKGEAIRIRAILRSLIPIEDLEGVISIPFPMPTVAKDGTVVEPDMSAGFCPDHKAAM VLFLDRVYGIEDQNFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLL TKCAPLFAGTEPYASLIDSLLHTVYRLSKGCCLTKAQRDAIEECLLAVCGKLRPSMMQHL LRRLVFDVPLLNEHTKMPLKLLTNHYERCWKYYCLSGGWGSFGAASDEELHLSRKLFWGI FDALSQKRYDQELFKLALPCLSAVAGALPPDYMESSYVAMMEKQSSMDAEGNFNPQPADT SNITIPEKLDYFINKYAEHSHEKWSMEKFANNWVHGDQLCESSKVHPLLKPYKALSEKEK ELYRWPIKESLKTMLAWGWSIERTREGETVGLHNRARRISQSSQLSVEGAHGFSPRPIDM SNVTLSRDLHSMAELLAENYHNIWAKKKKLELEAKGGGSHPLLVPYDTLTAKEKSKDREK AQDILKFFQINGYAVSRAMKEQELDTPSIEKRFAYTFLQQLITYVDEAHEHMLEFDLAAR AKGEKIPHEQQMKFFGKVVLPLIDQYFKNHRLYFLSTAIRPLNSGGHASNKEKEMVTSLF CKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGSETVKAALRAFFDNAAEDL ERTMENLKQGQFAHTRIQPKGVTQIINYTTVALLPVLSSLFEHIGQNLFGEDLILDDVQV SCYRILNSLYSLGTSKSIYVERQRPALGECLAAFSGAFPVAFLEPHLNKHNMYSIYNTKG SRERAALGLPAQVEEVNPLVPSLEKLLEEIMELAESGVRYTQMPHVMEVVLPMLCSYMSH WWEHGPEGGPEGGLERAERCCTLLTSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQ PIIGKAKPQLLKTHFLPLMEKLKKKAATVLLDEENMKAEGRGEMSEAELLILDEFTILVR DLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIFWAKSHNFKREEQNFVVQNE INNMSFLITDTKSKMSKGAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPVGLNICAPG DQELIALAKNRFTQKDTEDEVREIIRNNLHLQGKLEDPAIRWQMALYKDLPNRSEDTSDP EKTVERVLDIAHVLFHLDQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRA VNLFLQGYLKSWIEAEEHYFEDKLIEDLAKPGEQEMSEEDEGVKRIDPLHQLIQLFSRTA LTEKCKLEEDMLYMAYADIMAKSCHDEEDEDGEEVKSFEEKEMEKQKLLYQQARLHDRGA AEMVLQTISASKGEMGPMVASTLKLGIAILNGGNSTVQQKMLDYLKDKKDVGFFQSLAGL MLSCSVLDLNAFERQNKAEGLGMVTEEGSVITHERGEKVMQDDEFTCDLFRFLQLLCEGH NSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDIIDEQGQRNFSKAI NVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQIELLKE LMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLKDLTSSD TFKEYDPDGKGVISKRDFHKAMETHKHYTQSETEFLLSCAETDENELLDYEEFVERFHEP AKDIGFNVAVLLTNLSEHMPHDTRLQTFLELAESVLNYFQPYLGRIEIMGSAKRIERVYF EISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAAQMSDAG ERSASKEESEKEKPEEENPDMGFFSVTTVRTALLALRYNVMLLMKVLSMKSLKKQMKKMK KMTVKDMVMALISFYWSVLMGLFHFTFSVSRGFFRIMYSTFLGGSLVEGAKSMKVADLLA NMPDPTQDEVRGEGEEAEKRHTDKSSAQEDLADLAVAADDSDLLSDIFGLDLRREGGQYK LMPHNPNASITDLLTTPAVPVPTPSPEFRRRQGKGSTDEESKGKEDGKCEPEKAEGEDGE KNGKPKDSKPKQKVRRHHTSKSEETDLQESAFWKKIIAYQRKLLNYFARNFYNMRMLALF VAFAINFILLFYKVSTSSAVLEEKEVVYGGLPTDPKMRWSPAEGVPQRTVTVHFVLEESS GYMEPTLRILAILHTVIAFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDD IKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGHDRISELLGMDKAALDFSDAHEK KKPKKDSSLTAVLNSIDVKYQIWKLGVVFTDNSFLYLAWYMTMSILGHYNNFFFAAHLLD IAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGESPDMK CDDMLTCYMFHMYVGVRAGGGIGDQIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGL IIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFVMYL INKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 14889 nt NT seq  +upstreamnt  +downstreamnt atggccgaggggggggaaggagaagacgagatccagttcctgcggaccgatgacgaggtg gtacttcagtgctctgctaccatcaacaaggagcaacagaagctctgcctggctgctgag ggctttggaaaccggctctgcttcctggagtctacttccaactccaagaatgttcctccg gacctgtctatttgcacctttgttctggagcagtcgctatctgtccgggctctgcaggag atgctggccaacactgaagagaaagcagaagggaaattcatgatgaagactgctcaaggg ggaggacatcgtacactgctgtatggccatgccgtactgctccggcactcctacagtggg atgtacctttgctgtttgtccacttcacggtcctcaactgacaaactggcatttgatgtc ggactgcaagaagacacaacaggtgaggcctgctggtggaccattcatcctgcttccaag cagaggtcagagggagaaaaggtgagggtgggggacgacttgatcctcgtcagcgtctca tcagaacgctatctgcacctgtcgtacgggaatgggagcctgcatgtagatgccgccttc caacagaccctgtggagcgtggctcccatctgctctgggagtgaagttgcacaagggtac ctgattggtggcgatgtgctgagactgctgcacggccacatggatgagtgcctgactgtc ccatcaggggatcatggagaggagcagcgcaggacagtgcactatgagggaggtgctgta tccatccacgctcggtccctgtggagactggagaccctccgtgttgcgtggagtggcagc catacccgatggggccagccattccgcctgaggcacgtcaccactgggaagtatctcagt ctcacagatgaccggggcctcctgctcatggacaaggagaaagctgatgttaagtccaca gccttttgcttccgttcctcaaaggagaagctggacttgggagtgaaaaaggaggtggac ggcatgggtgtcgctgaaatcaagtacggcgactccgtctgttacgtccagcatgtggac acctgtctgtggctcacatatcaggctgtcgatgccaagtgtgcgcgaatgggaggcgtg cagcggaaggccatcatgcaccatgaaggtcacatggatgatgggctgaccctgtcacgg tcgcaacatgaggagtcgcgcacggcccgagtcatccgcagcaccgtctttctctttaat cgcttcatcaggggacttgatgcactgagtaaaaaagggaagatctccacgctggacctg cccattgagtctgttagcttaagtctgcaggacctgattggctatttccagccaccagat gagcatctggaacatgaggacaagcaaaacaggttgcgagccctgaagaatagacagaat ctcttccaggaagaaggcatgattaacttggtcctggaatgcattgatcggctgcatgtg tatagcagcgctgctcactttgccgacgtggccgggaaggaggctggagtggcctggaag tccatactgaactcattgtatgagctactggctgctttgatacgcggaaaccggaaaaac tgtgcccagttctcaggctcgctggactggttgatcagcaggctggagagactggaagcc tcctctggaatcctagaggtcctacactgtgtccttgtggaaagtccagaagctctcaac atcatcaaagagggacacattaagtcgatcatttccctcctggacaaacatgggcggaat cataaggtccttgatgtactctgctcactgtgtgtgtgccacggggttgcggtgagatcc aaccagcacctcatttgcgacaacctgctgcccggccgagatctgctgctccaaacaagg ctggtgaaccatgtcagcagtgtgaggccaaacatcttcctgggcatcagtgaaggttcc gcccagtacaggaaatggtactacgaacttattgtggaccacgtggagccctttgtcacg gctgaggcgactcacctgcgtgtgggttgggccacgactgatgggtattccccctaccca gggggtggagagggctgggggggcaacggcgtgggggacgacctctattcctatggtttt gatggacttcacttgtggtcaggttgcattgcgcggacagtgaactcacccaatcaacac ctcctccgagtggacgatgtggtcagctgctgcctggaccttggtgcacctagcatctca ttccgtatcaacggccagcccgtccaaggcatgtttgagaacttcaatgcagatgggctt ttcttccccgtcgtcagtttctcaactggggtgaaagtacgctttctgttgggtggccgc catggggaattcaagttcctgccccccccagggtatgccccctgctttgaggctgtgctg cccagggagaagctgagggtggaacacagccaggaatacaagcaggaccatagtgggaca cgagacctcctcgggcccatcatcactctcacacaagcagccttcactcccacacctgta gacaccagccagatcgttttgccacctcacctggaacaaatccgggagaagctagctgag aacattcatgaactgtgggtcatgaacaagattgagcttggctggacgtacgggacggta cgagatgataacaaacgacagcatccttgcctggttgagttctcaaagcttccagaacag gaacgcagctataacctgcagatgtccctggaaacactgaagacactgctcgcccttggg tgccatgtgggagtggcagacgaacacacagaggaaagagtgaaaaggctgaagctgtct gccaactatgagttgtcaagtggatacaagccagcccctatggacctgagccacatcaag ctgtcttccacccaagaggccatggtggacaagctggcagagaatgcacacaatgtatgg gctcgtgataggatccgccagggctggacctatggaatccaacaggatgtgaaaaacaga agaaaccctcggctggttccatacgccttgttagatgagcgtaccaagaagtccaacaag gacagcctgagagaggctgtccgaactttgctgggctatggctacaatctggaggcaccg gaccaagaccatgctgctaggtccgacatcagcaacatgttagccgagaggtttcgcatc ttccgcgcagagaagacctacagcgtcaatgccgggaaatggtactttgagtttgaggtt gtgacggcaggggagatgagggtgggctgggctcgaccaggctgtctgcctgaccaggag ctgggatccgacgaccaggcgtttgtcttcgatggcttcaaagcacagcggtggcaccag ggaaatgagcactttgggcggtcctggcagcctgctgatgtggtgggatgtatggtggac atgaacgaacgcaccatgatgttcacactcaatggcgaagtgctgctcgatgactctggc tccgagctggcgttcaaagactttgaggtttgggaaggatttatccctgtgtgcagccta ggtgtgtgccaggtaggcaggatgaatttcgggaaggatgtgagcaccctgaagtatttc acaatctgcggcctgcaggagggctttgagcccttcgctgtcaacatgaacagagatctg accatgtggtttagcaagaggctgccacagttcattcccgtccctcagaaccatgaacac attgaggtaacaaggattgatggaactattgaaagctcaccctgtctgaaggtcacacaa aggtcatttggctcacagaacagcaacagggacatcgtgttttaccgactgagcatgcca attgagtgcgcagagggcttctccaaatcactatgtggcataccttccaacggcagcttc ttttctcccaagaaggagctggatgactttgagactgtttcggactttgaggtcctcatg aaaactgctcatggacacttaagctccaacggccctgagaaagacaaggatgagttcaat aatcacaaagattacaaccaggaaaagccatcaaaattgaagcaaaggttcatgctaaag aggaccaagcctgacttaagtaccagtcactcttcccctcgtctgtcagaggaagtgctg gctgatgagcgggatgactatgaatatctgatgcagacttcaatgtactattactctgtg aggatcttcccaggccaggaaccctctagtgtgtgggtgggctgggtgacctctgatttc caccagtatgacacagcttttgatctggagaaggttcgcacggtgacggtcacccttgga gatgagaaggggaaggtccatgaaagcatcaagcgcagcaattgctacatggtctgggca ggagagagcacaagtcctggacagagccgcaacagcaatgggttggagatcggctgtctg gtggacacttctcatggattgctgaccttcaccagcaatggcaaagagctcagcacctac taccaggtggaacccagcaccaaactgttccctgcagtgttcgctcaagccaccagcccc agcgtctttcagtttgaattgggccggatcaagaatgtgatgcctctctcggcgggcctc tttaagagtgagaggaagaacgccatccctcagtgcccaccccggctgcatgtgcagttc ctgacccccgtgctgtggagtcgagtgccaaaccacttcctggaggtggaggcatcccgc atcaatgaccgccatggctggctggtgcagtgctccaaaccgctacagttcatgtcccta cacatccctgaggagaacagatctgtggacatcctggagctgacagagcagaaggatttg ctaaagtttcattaccacacccttcggctctactctgcggtgtgtgccctggggaacaac agggtggcccatgcactctgcagccatgttgatgaggcccagctgctctatgccattgag aacaaatacatgccaggtctgctacggacgggttactatgagctgctcatcgacatccat ctgagcacctatgccacggcgcgactcatgatgaataatgaatacattgtgcccatgacg gaggagacgaagagcatcaccctcttcccagacgagaagaagaagcatggcctgccgggg attggcctgagcacctctctgcggcctcgcatgcgctactcttcccctaactttgtcggt gttggtggggacttctaccagcacagtcctgagttccctttggaagtcctcaagagcaag acaattgagatgttgaccgaggctgtccaggagggcagcctgcatgtgcgtgaccctgtt ggtggaagcactgagttcctttttgtgccactcataaagcttttctatactctgctcatc atgggagtcttccacaatggggacctgaagaatatcctgcagcttattgagcctagtgta ttctctgagggcccgggccatgagcgggctgaaacccctgactgcggtggattcaaggct gagctccagataaatggtgtgggtggagaagatgacgggaggtcaggaaaagtccccaaa gtgggattgctccagatgaagctccccgagcccgtcaaacttcaaatgtgccaccttctg cagtacctgtgcgactgccaggtgaggcataggattgaggcggtggtggccttctctgat gacttcgttgccaacctccaggagaaccagcgctttcgctataatgaggtgatgcaggcc cttaacatgtctgctgccttgacagccaggaagacaaaagaatttcgctcacctccccag gaacagatcaacatgctgctgaattttaaagatgagaagcaggactgtccatgcccggag gatatccgagagcagttgctggacttccatgaagatctgatgaagcactgtggcatcgag atcgatgatgacaagacaaatgaggcagatggtgacttcaccatcaggggccggcttttg tcccttgtagagaaagtggcatacctgaagaagaaaagagctgacctacctaagaaaaaa aaggccaaaaagcccactacactgcagcagctgatctcggagaccatggtgcgctgggcc caggagtcggtgatcgaggacccagagctggtccgggccatgtttgtgctcctgcaccgg cagtatgatggcattgggggacaggtgcgcgccctgccgaagacctacaccatcaactcg gtgtctgtggaggacaccatcaacctgctggcctcgctgggccagatacgctccctgctg agtgtgcgcatgggccgtgaagaggagaagctcatgatccggggcctgggtgatattatg aacaataaagttttctaccagcacccaaatttaatgagagcactgggtatgcatgaaaca gtcatggaagtgatggtgaatgtgcttggaggaggagaatccaaggaaatcacatttcct aagatggtggccaactgctgtcgttttctttgctacttctgtcgcatcagtagacaaaac caaaaagccatgtttgatcatctcagttacttgctggaaaacagcagtgttggacttgcg tccccctccatgcgaggctccactcctctcgatgtggcagctgcctctgtgatggataat aacgaacttgccttggccctccgggagccagatctggagaaggttgttcagtatctggct gggtgtggccttcagagctgcctgatgctcgtgtctaagggctaccctgacattggctgg aaccctgtggaaggggagcgctacctggattttcttcgttttgccgtattctgtaatggt gagagtgtggaggagaatgccaatgttgtggtgaggctactgattcgcaggccagagtgt tttggccctgccctgcgtggggaaggtggcaatgggctcctagctgctatggaagaggcc atcaagatttcagaagaccccagcagggacggcccctctcccacctccgagtccagcagg accctcagtgatatgctggaggatgaagaggatgacaccatccacatgggcaatgccatc atgacattttatgcagcactaattgacctgctggggcgctgtgcacctgagatgcatttg atccatgccgggaagggagaggccattcggattcgagctatccttcgttctctgattccc attgaagaccttgaaggggtgatcagcatcccgttccccatgccaactgttgccaaagat ggaacagtggtggagccggatatgtcggcaggcttctgtccagaccacaaggcagccatg gtccttttcctcgaccgtgtgtatgggattgaggaccaaaacttcctgctccacctcttg gaggtggggttcctgccagacctccgagcagctgcatctctagatacggctgctctcagc gccactgacatggccctggcccttaaccgctacctgtgcactgccgtactgcccctgctc accaagtgcgccccgctgtttgccggcacggagccctatgcctcgcttatcgactcactg ctgcataccgtctaccggctgtccaagggctgctgcctgacgaaggctcagcgcgacgcc atcgaggagtgcctgctggctgtgtgtgggaaactgagaccctcgatgatgcaacacctg ctcaggcgattggtgtttgatgttcccctcctcaatgaacatactaagatgcctctcaag ctgctgactaaccactatgagcgctgctggaaatactactgcctatcagggggctggggg agttttggagctgcatcggatgaagagctgcacctttccaggaaactcttctggggaata ttcgatgctctgtcccagaagaggtatgaccaggaactcttcaagctggccctcccctgc ctaagtgctgtagctggggcactgcccccagactacatggagtccagctatgtggccatg atggagaagcagtcctccatggatgcagagggcaacttcaaccctcaaccggctgacaca tccaacatcacaatcccagagaagctggattactttatcaacaagtatgctgagcactct catgagaagtggtccatggaaaagtttgccaacaattgggttcatggggaccagctttgt gagtcctccaaagtgcatcctctgctgaaaccttacaaagccctgtctgagaaggagaag gagttgtaccgctggcccatcaaggaatccttgaaaaccatgctggcctgggggtggagc atcgagcggacgagggagggtgagactgtgggcttgcacaaccgggcacgacgcatctcg cagtctagccagctgtctgttgagggggcccatggtttcagcccaaggccaattgacatg agcaatgtgactctatccagagacctgcattccatggcagagcttcttgcagagaactat cataacatctgggccaagaagaagaaactggaacttgaagccaaaggaggagggagccac ccattactggtaccctatgacactcttactgccaaagagaaatccaaagacagagaaaaa gcacaagatatcctcaagttctttcagatcaatggctacgcagtctcacgggccatgaag gagcaggaattggacactccatccatcgagaagcgctttgcctacaccttcttgcagcag ctcatcacatacgtggatgaggctcacgagcacatgttagagttcgatctggctgctcgt gctaaaggggagaagattcctcatgaacagcagatgaaattttttggaaaggtggtcctg ccactgattgaccagtacttcaagaatcaccgtctctacttcctgtccacggccatccgt cccctcaatagtggaggtcatgcttccaacaaagaaaaggagatggtcaccagcttattc tgcaaactgggagttcttgtcagacataggatatcattgtttggaaacgatgctacctct attgtgaattgccttcacatcctgggtcaaacactggatgccaggacggtgatgaagacg ggttcagagaccgtgaaagctgcgttgcgggccttcttcgacaatgcagccgaggacctg gagaggaccatggagaacctgaagcagggacagtttgctcacacgcgcattcagcccaag ggcgtcacacagataatcaactacaccacagtggccctgctgcccgtgctctcatccctc ttcgaacacattggccagaacctcttcggtgaagacctgatattggatgatgtacaggtt tcatgctaccggatcctcaacagcctctattcacttgggaccagcaaaagcatctatgtt gaaaggcaacgaccggcacttggggagtgcctggcagctttctcaggggcctttcctgtg gccttcctggagccccacttaaacaagcacaacatgtactccatctataacaccaagggt tcccgcgagcgggcagcattagggctccctgcccaggtggaagaggtgaacccactagtg ccctccctggaaaagttgctggaggagatcatggagctggcagagtcaggcgtgcgctac acgcagatgccccatgtaatggaggtggtgttacccatgctctgcagctacatgtcacac tggtgggagcatggccctgagggtggccctgagggaggactcgagagagctgagcgctgc tgcaccttgctgacctccgagcacatgaacacgctgctgggaaacatcctcaagatcatt tacaacaacttgggcatagacgagggagcctggatgaagcgcctggcagttttctctcag ccgataatcggaaaggctaaaccgcagctgctgaagacccacttccttcctctgatggag aaactaaagaaaaaggcagcaacagtgctcctggatgaggagaacatgaaggcagagggg cgtggcgaaatgtcggaagctgagctgctcatcctggacgaattcaccattctagtgcgc gacctctatgccttctacccactcctcatccgatttgttgactacaacagagcaaaatgg ctcaaagagccgaacccagaggctgaagagctgttccggatggtggcggaggtcttcata ttttgggccaaatcccataacttcaaacgggaagagcagaactttgtggtccagaatgag atcaacaacatgtcattcttgatcactgacaccaagtccaaaatgtcaaagggtgcagtg tcagaccaagagaggaagaagatgaaaagaaagggtgaccgctactccatgcagacctcc ctcattgtagccgctctaaagaggcttctgcctgtgggtttgaacatatgtgcccctgga gaccaggagctgattgctctggccaagaaccgctttactcagaaagacacggaggatgag gtgcgagagatcattcgcaataaccttcatctgcagggcaagttggaagacccagcgatc cggtggcagatggcactgtacaaagacctgcccaaccgaagtgaggacacgtcagatcct gagaagacagtggaaagggttctggacatcgcccatgtgctcttccacttggaccaggtc gaacatccacagaggagcaagaaggctgtgtggcacaagttgctttccaagcagaggaag agagctgtggtggcctgcttccggatggcccccctctacaatctgcccaggcaccgtgct gtcaacctcttcctgcagggatacctgaagtcctggatcgaggcagaggagcattacttt gaggacaagttgatcgaggacttggcaaaaccgggcgagcaggaaatgtcagaggaagat gaaggagtcaagagaattgatcctctccatcagctgattcagctcttcagcaggaccgcc ctcacagagaagtgtaaactggaggaggatatgctgtatatggcttatgctgacatcatg gctaaaagttgccatgatgaagaggacgaagatggtgaagaggttaaaagctttgaagag aaagagatggaaaagcaaaagctgctctaccagcaggccaggcttcatgaccggggggca gctgagatggtcctgcagaccattagcgccagtaaaggtgaaatgggtcccatggtggca tccacactgaagttgggcattgccattttaaatggagggaattctactgtccagcagaaa atgctggattacctgaaggacaagaaggacgtgggcttctttcagagtctggccggccta atgctgtcctgcagcgtgcttgacctcaatgcctttgaacgacagaacaaagcagagggc ctaggcatggtaacggaggagggctcagtcatcactcatgagcgtggggagaaggtgatg caggatgatgagttcacctgtgaccttttccgattccttcagctcctctgtgaaggacac aactcagatttccagaattacctaagaacacagacgggaaacaacacaactgtcaacatc atcatctccacagttgattatcttctcagagttcaggagtctattagtgatttctactgg tattattctggaaaggacatcatcgatgagcagggtcaacggaacttctccaaagcaatc aatgttgccaagcaggtcttcaatactctcacagagtatatacagggcccatgcactggc aaccagcagagcctggcccatagccgactgtgggatgcagtggttggtttcctgcatgtg tttgctcatatgcaaatgaagctatcccaggattctagccagattgagttactcaaggaa ttgatggatcttcagaaggacatggttgtaatgttgttatcaatgttggaaggaaatgtc gtaaatggaactattggtaagcagatggtggatatgttagttgagtcctcaaataacgtg gagatgattctgaagttcttcgacatgttcctcaaacttaaagacctcacgtcatcagac acctttaaggagtatgatccagatggtaaaggggtcatctcaaagagggatttccacaaa gctatggagacccataaacactacacccagtcggagacggagttcctgctctcctgtgct gagacagatgagaatgagctgcttgactatgaggagtttgtagaaaggttccatgagcct gcaaaggatattggcttcaatgtggccgttctactgacaaacctgtcagagcatatgcca cacgacacacgactccagaccttcctggagctggcagaaagtgtacttaactacttccag ccttacttgggccgaattgagatcatgggcagtgccaaacgcattgagcgggtctacttc gagatcagtgagtccagtcgcacgcagtgggagaagccacaggtcaaggagtcaaagcgg cagtttatcttcgatgtggtcaacgaaggtggggagaaggagaagatggagctctttgtg aacttctgtgaggacacaatttttgagatgcagctggcagcccagatgtcagatgctgga gagcggtctgccagcaaggaggagagcgaaaaggaaaagcccgaggaggagaaccctgac atgggcttcttttctgtcaccacagtaaggactgcgctgcttgccctgcgctacaatgtg atgctgctgatgaaggtgctttccatgaaaagccttaagaaacagatgaagaagatgaag aagatgacagtgaaagacatggtcatggcgctcatctctttctactggagtgtgctgatg ggtctattccacttcaccttcagtgtgtcgcggggcttcttccgcatcatgtacagtact ttcctggggggcagcttggtggagggggccaagtcaatgaaggtggcagaccttttagct aacatgcctgatcccacacaggacgaggtccgcggggagggggaggaggctgagaagagg cacacggacaaatcctcagcccaagaagacctagctgacctagcagtggctgcagatgat tctgatctcctttcagacatatttggattagatcttaggcgggaagggggacaatacaag ctgatgcctcacaacccaaatgccagcatcactgatctactcaccactcctgctgttcct gttcccactccctcacctgagttcagaagacgacagggaaaagggtccacagatgaagag agcaaaggaaaagaagatggaaaatgtgagccagaaaaggcagaaggagaagatggagag aagaatgggaagcccaaagacagcaaacccaaacagaaagtcaggcggcaccacacctca aagtccgaggaaacagaccttcaagagtctgcattctggaagaagatcattgcttaccaa aggaaactgttgaattattttgcacggaatttctacaatatgcggatgttggccttgttt gtagcctttgccatcaacttcatccttctcttctacaaggtgtctacatcgtccgcagtg cttgaagagaaggaagtagtatatggcggcttgcctacagaccccaagatgcgatggagt cctgcagagggtgtgccccaacgaacagtgacagtgcactttgtcctggaggaaagcagt ggttacatggagcccacgctgcgcatcttggccatactacatactgtcattgccttcttc tgcatcatcggttactactgtttgaaggtgccgctggtgattttcaaacgggagaaggag gtggccaggaagctggagtttgatgggctctacataacggagcagccctctgaagatgac attaaagggcaatgggacaggcttgtaattaacacgcagtcattcccaaataactactgg gataaatttgttaaaaggaaggtgatggacaagtacggggagttctatggccatgaccgc atcagcgagctgctgggaatggacaaagccgccctggacttcagcgatgctcacgagaag aagaagcctaaaaaagacagttcgctgacggctgtactgaactccattgatgtcaagtat cagatctggaaactgggtgtagtcttcacagacaattccttcctctacttggcctggtac atgaccatgtcgatcctgggccactataacaattttttctttgctgcacacctcctggac attgccatgggtttcaagaccctgcgcaccatcctgtcctctgtcacacacaatggcaag cagctcgttcttacggtgggcttgctggcagtggtggtctacctctacacggtggtggcc ttcaatttcttccgtaagttctacaacaagagtgaagatggggagtctccggacatgaag tgcgatgacatgctcacgtgttacatgttccacatgtatgtgggagtccgtgccggaggc ggcatcggggaccagattgaggaccctgcaggggacgagtatgagatctacaggatcatt tttgacatcaccttcttcttcttcgtcattgtcattctactggccatcattcagggtctc attattgatgcttttggtgaactacgagaccagcaagagcaagtaaaagaagacatggag accaaatgtttcatctgcggaatcggaaatgactacttcgacacggtacctcatggcttt gagacccataccctacaggagcacaatttggcaaattatctcttttttgttatgtatctc attaacaaagatgaaacggagcacacgggccaggagtcgtacgtgtggaagatgtaccag gagcgatgctgggagttcttcccggccggagactgcttccgcaaacaatacgaagaccag ctcaactga

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