Salvelinus fontinalis (brook trout): 129843404 Help Entry 129843404         CDS       T11136                                  Name (RefSeq) ryanodine receptor 2-like   KO K04962   ryanodine receptor 2 Organism sfon  Salvelinus fontinalis (brook trout) Pathway sfon04020   Calcium signaling pathway sfon04260   Cardiac muscle contraction sfon04261   Adrenergic signaling in cardiomyocytes sfon04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sfon00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     129843404    04020 Calcium signaling pathway     129843404  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     129843404    04261 Adrenergic signaling in cardiomyocytes     129843404  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sfon04040]     129843404    04990 Domain-containing proteins not elsewhere classified [BR:sfon04990]     129843404 Ion channels [BR:sfon04040]  Voltage-gated cation channels   Ryanodine receptor    129843404 Domain-containing proteins not elsewhere classified [BR:sfon04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    129843404 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  129843404 NCBI-ProteinID:  XP_055768088 LinkDB All DBs Position Unknown AA seq 5000 aa AA seqDB search MADAGEAGEDEIQFLRTDDEVVLQCSATVHKEQQKLCLAAEGFGNRLCFLESTSNSKNVP PDLSICTFVLEQSLSVRALQEMLANTEEKAEGKFMMKTAQGGGHRTLLYGHAVLLRHSYS GMYLCCLGTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVSV SSERYLHLSYGSDSLQVDAAFQQTLWSVATVCSGSEVAQGFMIGGDVLRLLHGHMDECLT VPSGEHGDEQRRTVHYEGGAVSIHARSLWRLETLRVAWSGSHTRWGQPFRLRHVTTGKYL SIMEDKGLLLMDKEKADVKSTAFCFRPSKEKLDLGPKKEVDGMGVPDIKYGDSVCYIQHV DTCLWLTYQAMDAKCARMGGVQRKAIMHHEGHMDDGLTLSRSQHEESRTARVMRSTVFLF NRFIRGLDTLSIKGKTSTLDLPIESVSLSLQDLIGYFQPPDEHLEHEDKQNRLRALKNRQ NLFQEEGMINLVLECIDRLHVYSSAAHFAEVAGREAGEAWRSTLNSLYELLAALIRGNRK NCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIISLLDKHGR NHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGVSEG SAQYRKWYYELMVDQVLPFVTAEATHLRVGWATTDGYQPYPGGGEGWGGNGLGDDLYSYG FDGLHLWSGCISRTVSSPNQHLLRVDDVVSCCLDLSAPSISFRINGQPVQGMFENFNSDG LFFPVASFSAGVKVRFLLGGRQGEFKFLPPPGYAPCFEAVLPREKLRVEHSQEYKEDHSE TRDLLGPTITLSQAAFTPTPVDTSQVVLPPHLERIREKLAENIHELWVMNKIDLGWTYGA VRDDNKRQHPCLVEFSKLPEQERSYNLQMSLETLKTLLALGCHVGLADEHAVEKVKNLKL SATYELSSGYKPAPMDLGHIKLASTQEAMVDKLAENAHNVWARDRIRQGWTYGIQQVCHP KDVKNRRNPRLVPYTLLDERTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAARADVSNMS AERFRIFRAEKTYSVNAGKWYFEFEVLTSGEMRVGWARPGCLPDQELGSDQHAFVFDGFK AQLWHQGNEHFGRSWGPGDVVGCMVDLNEHTMMFTHNGEVLLDSSGSELAFKDFEVWEGF IPVCSLGVCQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNMNRDLTMWLSKRLSQFIPV PPHHEHIEVTRMDGTVETFPCLKVTQRSFGSQNSNPDITFYRLSMPIECNEVLAKSPGGT LQSGGGFSFSSKKDLDDFETVSDFEVLTKSAHCTLDSSLDKEKDQFNNHKDYNQEKPSKL KQRFLLKRTKPEFSSSTSSARLSEEVLADRDDLDFFMQTSTYYYSVRIFPGQEPSSVWVG WVTSDFHQYDMAFDLEKVRTVTVTLGDEKGKVHESIKRSNCYMVWAGESTSPGQGRNNNG LEIGCLVDTVNGLLTFTANGKELSTYYQVEPSTKLFPAVFAQATSPSIFQFELGRIKNVM PLSAGLFKSERRNSCPQCPPRLHVQFLTPVMWSRVPNHFLKVDVSRVNDRHGWLVTCSEP LQFMSLHIPEENRSVDILELTEQKDLLKFHYHTLRLYSAVCALGNNRVAHALCSHADEAQ LLYAIENKYMPGLLRTGYYDLLIDIHLSTYATARLMMNNEYIVPMTDETKSITLFPDEKK KHGLPGIGLSTSLRPRMHFSSPSFICSGADCFQFSPEFPLDILKTKTIEMLTEAVSEGSL HVRDPIGGSTEFLFVPLIKLFYTLLIMGVFHNGDLKNILQLIEPSVFSEGGDVTADTPAD TPESDVTKGGRGGEGPGGEERTGKVPKGLLQMKLPEPVKLQMCHLLQYLCDCQVRHRIEA VVGFSDDFVAHLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLSFKDEKV DCPCPEHIRGQLVDFHEDLMTHCGIEIDEDKLNEADSDFTIRGRLMSLVEKVVYLKKKMT FMPKNKKKDKKPSTLQQLISETMVRWAQESIMEDPELVRAMFVLLHRQYDGIGGQVRALP KAYTINSVSVEDTIKLLASLGQIRSLLSVRMGREEEKLMIRGLGDIMNNKVFYQHPNLMR ALGMHETVMEVMVNVLSGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLE NSSVGLASPSMRGSTPLDVAAASVMDNNELALALREPDLEKVVQYLAGCGLQSCSMLVSK GYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGL LAAMMEAIKISEDPCRDGPSPTSEANRTLSEVLLEDEEDDTIHMGNAIMTFYAALIDLLG RCAPEMHLIHAGKGEAIRIRAILRSLIPIEDLEGVISIPFPMPTLAKDGSVVEPDMSAGF CPDHKAAMVLFLDRVYGIEDQNFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYL CTAVLPLLTKCAPLFAGTEPYASLIDSLLHTVYRLSKGCCLTKAQRDAIEECLLATCGQL RPSMMQHLLRRLVFDVPLLNEHTKMPLKLLTNHYERCWKYYCLTGGWGSFGASSDEELHL SRKLFWGIFDALSRKRYDQELFKLALPCLSAVAGALPPDYMESNYVAVMEKQSSMDAEGN FNPQPADTTNVNVPEKLDYFVNKYAEHSHDKWSMDKFSNGWVHGDKVCEVSKAHPLLKPY KGLSEKDKELYRWPIKESLKTMMVWCWSIERTREGDPASLHNRGRRISQISQQHSVEGAP GFSPRPIDMSNVTLSRDLHSMAELLAENYHNIWAKKKKLELEAKGGGNHPLLVPYDTLTA REKYKDRGKAQDILKFFQINGYTVSRAMKEQELDTPSIEKRFAYTFLQQLITDVDGAHEH MLESDVGTPPKGESVPHEQQMKFFGKVVLPLVDQYFKNHRLYFLSTAIRPISSGGHASNK EKEMVTSLFCKLGLLVRHRISLFGSHATSIVNCLHILGQTLDARTVMKTGLETVKAALRA FFDNAAEDLERTLENLKQGQFTHSHSQPKGVTQIINYTSVALLPVLSSLFQHIGQNLFGE DLILDDVQVSCYRILNSLYSLGTNNSIYVERQRPALGECLAAFSGAFPVAFLEPELNKFN NYSIYITKGSRDRTALDLPSQVEEMCPAIPSLEKSLEEIMDLAESGLHYTQMPHVMEVVL PMLCSYMSHWWEHGPENNPPETADSCCTHLTSDHMNSLLGNILKIIYNNLGIDEGAWMKR LAVFSQPIIGKAKGGLLKTHFLPLMEKLRKKAATVLLDEEQMKAEGRGEMSEAELLILDE FTILIRDLYAFYPLLIRFVDYNRAKWLKESNPDAEELFRMVAEVFIFWSKSHNFKREEQN FVVQNEINNMSFLITDTKSKMSKGAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPVGL NICAPGDQELIALAKIRFSQKDTEDEVREIIRNNLHLQGKLEDPAIRWQMALYKDLPNRS EDTSDPEKTVERVLDIAHVLFYLDQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYN LPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLARPGGEEPPEEDEGAKRIDPLHQLIQ LFSRTALTEKCKLEEDILYMAYADIMAKSCHDEEDEDGEEVKSFEEKEMEKQKLLYQQAR LHDRGAAEMVLQTISASKGEMGPMVASTLKLGIAVLNGGNSTVQQKMLDYLKDKKDVGFF QSVAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSVITHERGEKVMQDDEFTCDLFRFLQ LLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQR HFSKAINVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSSQ IELLKELMDLQKDMVVMLLSMLEGSVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKLK DLTSSDAFKEYDPDGKGVISKRDFHKAMESHKHYTQSETEFLLSCAEPDENELLDYEEFV ERFHEPAKDIGFNVAVLLTNLSEHMPHDTRLQTFLELAESVLNYFQPYLGRIEIMGSAKR IERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLAA QMSDIGERSAVKEESEKEKPEEESPEMGFFSVTTVRTALMALRYNVMFLMNVLSMKSLKK QMKRMKKMTVKDMVMTLVSFYWSVVMGLFHFTFSVSRGFCRIMYNTFLGGSLVEGAKTMK VSDLLANMPDPTQDEVREEGEKALSARPSAEEELADLALPVDGTEVLSDIFGLDLRRGEG GQYKITAHNPNASLTDLLNSPVPSSPVRATSPSPELRRRHQAKSPSEEGRTGTEETKEAK SEPEKAEGLDGEKQEEEEERRKEEERRKEERRQEEKKRKEEKPKAKVRQQHTSKSDEHDM QESAFWKKIIAYQRKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSSSSAVMPESRRP RAGSSVRWDPVTEGSDTQEPQNPQQEPVFVHFVLEESTGYMEPTLRILAILHTVISFCCI IGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTGSFPNNYWDK FVKRKVMDKYGEFYGHDRISELLGMDKAALDFSDAHEKKKPKKDSSLAAVLNSVDVKYQI WKLGVVFTDNSFLYLAWYMTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQL VLTVGLLAVVVYLYTVVAFNFFRKFYNRGEEGETPDMKCDDMLTCYMFHMYVGVRAGGGI GDQIEDPAGDEYEIYRIIFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETK CFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFVMYLINKDETEHTGQESYVWKMYQER CWEFFPAGDCFRKQYEDQLN NT seq 15003 nt NT seq  +upstreamnt  +downstreamnt atggctgatgcgggagaagccggagaagatgaaatacagttcctacgaaccgatgatgag gtcgtcctgcagtgttctgccacagtccacaaggagcagcagaagttgtgtctggcagcg gagggcttcggaaacaggctctgcttcctcgagtcaacatccaactctaagaatgtccct ccagacctgtccatctgtacgtttgtcctggaacagtccctctcagtacgggccctgcag gagatgctggccaacacagaggagaaggcagaagggaaattcatgatgaagacggcccag ggagggggccaccgcaccttactgtacggacacgctgttctgctacgacactcctacagc ggcatgtacctctgttgcctaggtacctcccgatcgtcaaccgacaaactggcgtttgat gttggactgcaggaagacacaacaggagaagcctgttggtggactatccaccctgcctcc aagcagaggtcagagggagagaaagtccgagtcggggatgacctcatcctagttagcgtg tcatcagaacgatacctgcatctatcgtacggtagcgacagcctgcaggtggacgcagcc ttccagcagaccctctggagcgtggctaccgtctgctccggcagcgaggtggcccaaggg ttcatgatcggcggggacgtgctgaggctgctccatggtcacatggatgagtgtctgaca gtgccgtcgggagaacatggggatgagcagcgcaggacggtgcactacgaggggggagct gtgtccatccacgcccgctccctctggagactggagacgctacgagtggcgtggagcggc agccacacccgctggggtcaacccttccgtctccgtcatgtgaccacggggaagtacctc agtatcatggaggataagggcctgctgctgatggacaaggagaaggctgacgtcaagtct actgctttctgcttccgcccctccaaggaaaagctggacttggggccaaagaaggaggtg gatggcatgggtgttcctgatatcaagtacggggactcggtgtgttatatccaacatgtg gacacctgtctgtggctcacataccaggccatggacgctaagtgtgcgcgcatgggcggc gtgcagagaaaggccatcatgcaccacgagggtcacatggacgatgggctgaccctgtcc cgctcacagcacgaggagtcccgcaccgcacgggtcatgcgcagtaccgtcttcctgttc aaccgattcatcaggggtctggacaccctcagtataaaaggaaagacctcgacactcgac ctgccgatcgagtcggtcagtttgagcctgcaggatctgattggctacttccagcctccc gacgaacacctggagcacgaggacaaacagaaccgcctccgagccctgaagaaccgacag aacctcttccaggaagagggtatgataaacctggtgttggagtgtattgaccgtctccac gtgtacagcagcgcggctcattttgctgaggtggcggggagggaggccggggaggcctgg agatccacactaaactcattatatgagctcctggctgcgttgataaggggcaacaggaag aattgtgcccagttctccggctcgttggattggttgatcagccggctagagagactggag gcctcatctggtatcttggaggtccttcactgtgtcctggtggaaagtcctgaagctctg aacatcatcaaggagggacacatcaagtcaatcatctctctgctagacaaacatggacgc aaccacaaggttctggacgtgctctgttccctgtgtgtctgtcacggtgtggcggtacgt tccaaccagcacctgatctgtgacaacctgctacctggcagagacctgctgctacagaca cgacttgtcaaccatgtcagcagcatgaggcctaacatcttcctgggtgtgagtgaaggc tccgcccagtacaggaagtggtattacgagctgatggtggaccaggtgttacccttcgtt acggccgaagccacacatctcagagtgggctgggccaccacagacggctaccaaccctac cccggtggaggagagggctgggggggaaacgggctcggcgacgacctctactcctacggc ttcgacggcttgcacctgtggtcaggctgcatctccaggacagtgagctcaccaaatcaa catctcctccgtgtggatgacgtggtcagctgttgtctggacctcagtgctcccagtatc tcgttccgtatcaacggtcagcccgtccaggggatgtttgagaacttcaactctgacgga ctgttcttccctgtagccagcttctccgccggggtcaaagtgcgtttcctgctgggtggt cgtcaaggagagtttaagttcctgcccccgccgggctacgctccgtgtttcgaggctgtg ctacccagggagaagctgagagtggaacacagccaggagtacaaggaggaccacagtgag accagggatctactgggtcccaccatcaccctgtcccaggctgccttcacccctacacct gttgacaccagccaggttgttctgcctcctcacctggagaggatcagggagaagctggcg gagaacatccatgagctgtgggtcatgaacaagattgacctgggctggacctacggagct gtacgggacgacaacaagcggcagcatccttgtctggtggagttctccaagctgcctgag caggagaggagctacaacctacagatgtctctggagactctcaagactctcttggccctg ggttgccacgtgggtctggctgacgagcacgctgtggagaaggtgaagaacctcaagctc tctgccacttatgagctgtctagtggctacaagcctgctcctatggatctgggccacatc aagctggcctctacccaggaggccatggtggacaagctggcggagaacgctcacaatgtg tgggccagggatcgcatacgccagggctggacctacggcatccagcaggtgtgtcaccca aaggatgtgaagaatcgtaggaacccgcgcttggttccgtacactctgctggacgagagg accaagaagtccaacaaggacagtctgagggaggctgtccgcaccctgctggggtacgga tacaacctggaggctccggatcaggaccatgcagccagagcagacgtcagtaacatgtct gctgagcggttccgtatcttccgagccgagaagacgtacagtgtgaacgctgggaagtgg tactttgagtttgaggtgctgacgtcaggggagatgagggtgggctgggcgcggccgggc tgtctacctgaccaggagctgggctctgaccaacacgccttcgtcttcgacggattcaag gcccagctgtggcaccagggcaacgagcacttcggcaggtcgtggggtccaggtgacgtg gtgggctgtatggtcgatctgaacgaacacactatgatgttcacccacaatggagaggtg ctcctggacagctcaggctctgaactggccttcaaggactttgaggtctgggaaggtttc atcccggtctgcagtctgggtgtttgccaggttgggaggatgaactttggtaaagacgtg agcacgctgaagtacttcacgatctgtgggctgcaggaaggatacgagcccttcgccgtc aacatgaacagagacctcaccatgtggctcagcaagagattgtctcagttcatccctgta cctcctcatcatgaacacattgaggtgacgaggatggacggcaccgtggagactttcccg tgtctcaaggtcacccagaggtcgttcggctcccagaacagtaacccagacatcaccttc tatcgcctcagcatgcctatagagtgtaacgaggtgctggccaagtcacctggcgggacg ctacagtctggcgggggcttctccttctcctctaagaaagacctggatgacttcgagacc gtgtccgacttcgaggtgttgacgaagtctgcccactgcaccctggactccagcctggac aaggagaaggaccagttcaacaaccacaaagactacaaccaggagaaaccctccaagtta aagcagagattcttgttgaagaggaccaagccagagtttagcagcagtacctcttcagcc cgtctatcagaggaggtgttagctgacagagatgacctggacttcttcatgcagacctcc acttactactactcagtgaggatcttcccaggtcaggagcccagcagtgtgtgggttggc tgggtgacctctgacttccaccagtacgacatggccttcgacctcgaaaaggtccgcacc gtcaccgtaaccctgggagacgagaagggcaaagttcacgagagcatcaagcgtagtaac tgctacatggtgtgggctggagagagtacgagtcctggtcagggccggaacaacaacggc ctggagattggatgtctggtggacacagttaacggactactaaccttcactgccaacggg aaggagctcagcacatactaccaggttgagcccagtaccaagctgttccctgctgtgttc gctcaggccaccagccccagcatctttcagtttgaactaggacgtattaagaacgtcatg cctctgtcagcgggactgtttaagagtgagaggaggaactcctgtccccagtgtcctccc aggctgcatgtccagttcctgaccccggtgatgtggagcagggtacccaaccacttcctc aaggtggacgtgtcccgagtcaacgaccgccatggctggctggtcacctgctctgaaccg ctccagttcatgtccctgcatatacctgaggagaacaggtcagttgatatcctggagttg actgagcagaaggatctgttgaagtttcactaccatactctgaggttgtactctgctgtg tgcgctctggggaacaaccgtgtggcccacgccctctgctcccacgccgacgaggcacag ctgctctacgccatagagaacaagtacatgcctggtctcctcaggactggatactacgac ctgctcatagacatccacctcagtacctatgccacggcgcgtctcatgatgaacaatgaa tacatcgtccccatgacggacgagaccaagtccatcactctgttccccgacgagaagaag aagcacggtctgccggggatcggcctgagcacctctctccgcccccgcatgcacttctcc tcgccgtccttcatctgcagcggagccgactgcttccagttcagccccgagttccccctg gatatcctgaagaccaagaccatagagatgctgacggaggccgtgagcgaggggagtcta cacgtcagagatcctatagggggcagcactgagttcctgttcgttcctctcattaagctg ttctacacgttactgatcatgggagtgttccataacggagacctgaagaacattctacag ctgatagaacccagcgtgttctcagagggaggggacgtgaccgcggacacgcccgcggac acgcccgagagtgatgtcactaagggaggaagaggcggggaggggcctggaggagaggag aggacagggaaggtccctaaaggactactacagatgaaactaccggagcctgtcaaactg cagatgtgccacctgctccagtacctgtgtgactgtcaggtgcgccaccgtatcgaggcg gtggtgggcttcagcgatgacttcgtggctcatctccaggacaaccagcggttccgctac aacgaggtcatgcaggcgctcaacatgtcggccgccctgactgccaggaagaccaaggag ttcagatcccctcctcaggaacagatcaacatgctcctgagctttaaggacgagaaggtg gactgtccctgcccagaacacatcagaggacaacttgtagacttccacgaggacctgatg acacactgtggcatagagatagacgaggacaagctgaacgaggcagacagtgacttcacc atccgaggaagactcatgtctctggtggagaaggtggtctacctgaagaaaaagatgacc ttcatgccgaagaacaagaagaaagataagaaacccagcacgttgcagcagctgatcagt gagaccatggtacgctgggcccaggagagcatcatggaggacccagagctggtcagagcc atgtttgtcctcctccaccgtcagtacgacggtatcgggggccaggtccgagccctgccc aaggcctacaccatcaactcagtctctgtggaggacaccatcaaactgctggcgtcactg ggacagatcagatcactgttgtctgtacgcatggggcgtgaggaggagaaactgatgatc agaggactgggagacatcatgaataacaaggtcttctaccagcaccccaacctgatgaga gctctgggaatgcatgagaccgtcatggaggtgatggtgaacgtcctgagtggaggggaa tccaaggaaatcacctttcctaagatggtggccaactgctgtcgtttcctgtgttacttc tgccgcatcagcagacagaaccagaaggccatgttcgaccacctcagctacctgctggag aacagcagcgtcgggcttgcgtctccctccatgcgaggctctactccactagacgtggcc gctgcctctgtgatggacaacaacgagctggctctggccctgagggaaccagacctggag aaagtggtgcagtacttggctggctgtggtctccagagttgctccatgctagtgtctaaa ggatacccggacatcggctggaaccctgtcgaaggagagagatacctcgacttcctccgc ttcgcagtgttctgcaacggtgagagtgtggaggagaacgctaacgtggtggtgaggctg ctgattcgtcggcccgagtgctttggccccgccctgcgcggagagggggggaatggtctc ctagcagccatgatggaagccatcaagatatcagaggacccctgtagagacgggccctcc cctacctcagaggccaacaggacactcagtgaggtgttattggaggacgaggaagatgac actattcacatgggaaacgctataatgaccttctacgcagccctcatagacctgctgggt cgctgcgcccctgagatgcacctgatccatgctgggaagggtgaggccatcaggataaga gccatcctacgttccctgatccctatagaggacctggaaggagtgatcagcatccccttt cccatgccaaccctggccaaagatgggtcagtggtggagcctgatatgtcagctgggttc tgtccggaccacaaggcagccatggtgctgttcctggaccgggtctacgggatagaggac cagaacttcctgcttcatctgctggaggtgggcttcctgcctgacctcagggctgctgcc tcgctcgacacagctgctctgagcgctacagacatggccctggccctcaacaggtacctg tgtacagcggttctgcccctgctcactaaatgtgccccgctgttcgctgggacagagccc tacgcctcgctcatagactctctacttcacaccgtctaccgtctctctaagggatgctgc ctcaccaaggcgcagagagacgccatcgaggaatgtctgctggccacctgtggtcagctg aggccgtccatgatgcagcacctgctgagacgcttggtgtttgatgttcctctcctcaac gaacacaccaagatgcctctcaagctgttgaccaatcactacgagcgttgctggaagtac tactgtctgacgggcggctgggggagctttggggcgtcgtcggacgaagagctgcatctc tccaggaagctgttctggggcatcttcgacgctctgtctcgtaagaggtatgatcaggag ctgtttaagctagctctgccgtgtctaagtgccgtagccggggcactaccacctgactac atggagagtaactacgtggccgtgatggagaaacagtcctctatggacgcggagggaaac ttcaacccacagcctgcagacaccaccaatgtgaacgtcccggagaagctggattacttt gttaataaatatgccgagcattcccatgacaagtggtccatggacaagttttccaacggt tgggttcacggggacaaggtctgtgaggtctctaaagcccaccctctcctcaagccctat aaagggctgtcagagaaggataaagagttgtaccgctggcctatcaaggagtctctgaag acgatgatggtgtggtgctggagcatagagaggaccagggagggagacccagccagccta cacaacagaggacgtaggatctctcagatcagccagcaacactctgtcgaaggagctcca ggtttcagccccagacccatcgacatgagcaatgtgacactgtcccgggacctgcactct atggcagaactgcttgcagagaactatcataatatttgggcgaagaagaagaagctggaa ctagaagccaaaggaggagggaaccatcccttactggtgccctatgacacgctcaccgcc agagagaaatacaaagacagaggaaaagcccaagacattctcaagttctttcagattaat ggctacactgtatccagggccatgaaagagcaggagctggataccccctccatagagaag cgttttgcctacacctttctgcagcagctcatcactgatgtagacggggcccacgaacac atgctggagtctgacgttgggacaccaccgaaaggagagagcgttcctcacgagcagcag atgaagttttttggaaaggtggtcctgccattggtcgaccagtacttcaagaatcaccgc ctctacttcctttccacggccatccgaccaatcagcagcgggggccacgcctccaataag gagaaggagatggtgacaagtctgttctgcaaactgggacttcttgtcagacataggata tcattgtttggaagccatgctacctccatagtcaactgtcttcacatactgggccagacg ctcgacgccaggacggtgatgaagacgggtctggagacggtgaaggcggcgttgagggcg ttctttgacaacgcagcggaggacttggagaggactttagagaacctgaaacagggacag ttcactcacagtcactcccagcccaaaggagtcacccagatcattaactacaccagcgta gccctgctcccggtcctgtcctccctgttccaacacatcgggcagaacctctttggggaa gacctcatattggatgacgtccaggtgtcgtgttacaggatactcaacagcctgtatagt cttggtaccaacaacagcatctacgtggaaaggcagcgtccagccctaggtgaatgtctt gcagcgttctcgggggcgttccctgtggccttcctggaacctgagctcaacaagttcaac aactactccatctacattaccaagggctcccgggacagaacagctctagacctgccctcc caggtagaagagatgtgtccagccatcccgtccctggagaagtctctagaggagatcatg gatctggctgagtccggcctgcactacacacagatgcctcacgttatggaggtggtgctg cccatgctatgcagctacatgtctcactggtgggagcacggcccagagaacaaccctcca gagactgcagacagctgctgtactcacctgacctcagaccacatgaatagtctactgggc aacatcctgaagatcatctacaataacctggggatcgacgagggggcctggatgaaacga ctcgcagtgttctctcagccaatcatcggtaaggcgaagggggggctgttgaagacccac ttcctgccgctgatggagaagttgaggaagaaggctgccaccgtactgctggatgaggaa caaatgaaggctgagggacgaggggagatgtctgaggctgaactactcatcctggatgag tttaccatcctgatcagagacctctacgccttttatccgctactcatccgctttgtagac tacaacagggccaaatggctgaaagaatcgaaccctgatgctgaggagctcttccgcatg gtagcagaggtcttcatattctggtccaagtctcataattttaaacgggaggagcagaac tttgtggttcagaatgagatcaacaatatgtccttcctcatcacagacaccaagtcaaag atgtccaagggagccgtgtccgaccaggagaggaagaagatgaagaggaagggtgatcgc tactccatgcagaccagcctcatcgtagcagcgttgaagagactacttcctgtaggactg aatatctgcgctccgggagaccaggaactgatcgctctggccaagatccgcttcagtcag aaagacacggaggacgaggtgcgggagatcatcaggaacaacctgcacctgcagggaaag ctggaggaccctgctatccgctggcagatggctctgtataaggaccttcctaacaggagt gaggacacgtcagacccagagaagactgtagagagagtcctggacatcgctcacgtcctc ttctatctagaccaggtggaacatccacaaaggagtaagaaggctgtgtggcacaagctg ctctctaaacagaggaagagggctgtagtggcctgtttcagaatggctccgctgtataac ctacccaggcaccgggcggtcaacctgtttctacagggatatgagaagtcctggatcgag actgaggagcactactttgaggataagcttatagaggacctggctagaccgggaggagag gagcctcctgaagaagatgagggagccaagaggatcgaccctcttcatcagctcatacag ttattcagtaggacggccctgactgagaagtgtaagctggaagaggacattctctacatg gcctatgctgacattatggctaagagctgtcatgatgaagaggatgaggatggagaggag gtgaagagttttgaagaaaaagagatggagaaacagaagctgttatatcagcaggccagg ttacacgaccgtggtgctgcggagatggtgctgcagactatcagcgccagcaaaggtgag atgggtcccatggtggcctctactctgaagctggggatcgctgtcctcaatggaggcaac tctactgttcagcagaaaatgctggactacctgaaagacaagaaggatgtcggtttcttc cagagtgtggctggtctgatgcagtcatgcagtgttctagacctgaatgcgtttgagcga cagaataaagcagagggcctgggcatggtgacagaggagggatcagtcatcactcatgag cgtggagagaaggtgatgcaggatgatgagttcacctgtgacctgttccgcttcctccag ctgctctgtgaaggtcacaactcagactttcagaattacctgagaacacagacagggaac aacactacggtcaacatcatcatctctaccgtcgactaccttcttagagttcaggaatca atcagtgatttctactggtactattcggggaaggacgtcattgacgaacaaggacagcgt catttctccaaggcgattaacgtggcaaaacaggtcttcaatactctcacggagtacata cagggaccgtgtactgggaaccagcaaagtctagctcacagccgtctgtgggacgctgtc gttggcttcctccatgtcttcgctcacatgcagatgaagctgtcacaggactcgagccag atagagttgttgaaagagttgatggatctgcagaaagacatggttgtgatgttgctgtcc atgctggaaggcagcgtggtcaacggaaccatcgggaagcagatggtagacatgttggtc gagtcctccaacaacgtggagatgatcctcaagttcttcgacatgttccttaaactcaaa gacctgacgtcgtccgacgccttcaaggagtatgacccggatggtaaaggggtcatctcc aagagagacttccacaaagccatggagagccacaagcactatacccagtctgagacggag ttcctgctctcctgtgctgagcctgacgagaacgagctgttggactacgaggagtttgtg gagcgtttccacgagccggccaaagacatcggcttcaacgtagccgtgcttctgaccaac ctgtctgaacacatgcctcacgacacgcgcctacagaccttcctggagctggctgagagt gtgctcaactacttccagccgtacctgggccgtatcgagatcatgggcagtgccaagcgt atcgagagggtctacttcgagatcagcgagtccagtcggacacagtgggagaagccccag gtcaaagagtccaaacgccagttcatcttcgacgtggtcaacgagggcggggagaaggag aagatggagctgttcgttaacttctgcgaggacaccatctttgagatgcagctggccgcc cagatgtccgacatcggggaacggtcggccgtgaaggaggagagcgagaaagagaaaccg gaagaggagagtcctgagatgggtttcttctccgtgaccacggtccggaccgccctgatg gcgctacgctacaacgtcatgttcctgatgaatgttctgtccatgaagagcctgaagaag cagatgaagagaatgaagaagatgacagtgaaggacatggtgatgacgctggtctccttc tattggtccgtcgtcatgggcctgttccacttcaccttcagcgtctccagagggttctgc agaatcatgtacaacaccttcctaggaggcagtctggtggagggagccaagactatgaag gtgtctgacctgttggccaacatgcctgacccgacccaggatgaggttcgagaggagggg gagaaggcgctctcagctagaccctcggctgaggaggagctggcggatctagccctgccc gtggacgggacggaagtcctctcagacatctttggattagatctgaggagaggagaagga ggacagtataagataactgctcacaaccccaacgccagtctgactgatctgcttaactct ccagtcccctcctctcctgtccgcgctacctcaccgtccccggaactgagaagaaggcac caggctaagagcccttcagaggaagggaggacagggactgaggaaaccaaggaggccaag tcagagccggagaaagcagagggactggatggagagaagcaggaggaggaggaggagagg aggaaggaggaggagaggaggaaggaggagaggagacaggaggaaaagaagaggaaggag gagaagccgaaagctaaagtgagacagcagcacacctccaagtctgatgagcatgacatg caggagtctgccttctggaagaaaatcatcgcctatcagaggaagctgctgaactatttt gctcggaacttctacaacatgagaatgctggcattgtttgtggccttcgccatcaacttc atcctcctcttctacaaggtgtcctcctcctcagcggtgatgcctgaaagcagaaggccc cgggcaggcagcagtgtgcggtgggaccccgtgacggagggtagtgacacccaggagcct caaaacccccagcaggaacctgtgtttgtccactttgtgctggaggagagcaccggatac atggagcccaccctgcgtatcctggccatcctacacactgtcatctccttctgctgcatc ataggttactactgccttaaggtcccgttagtgatcttcaagcgtgagaaggaggtggcg aggaagctggagtttgacggtctctacatcacagagcagccgtcggaggacgacattaaa ggccagtgggaccgactagtgattaacactggatcgtttcccaacaactactgggataag tttgtgaagaggaaggtgatggataagtatggagagttctacggccatgaccgcatcagt gagctgctgggtatggacaaggctgctctggacttcagtgacgcccacgagaagaagaaa cccaagaaagacagctcgttagccgcagtattaaactctgttgatgtcaagtaccagatc tggaaactaggagtcgtcttcacagacaattcgttcctgtacctggcttggtatatgacc atgtccatcctgggtcactataacaacttcttctttgctgctcatctcctggacatcgcc atgggcttcaagaccctccgcaccatcctgtcttctgtcacgcacaacggaaaacagctg gttctgacagtaggactactggctgtggtggtgtatctctacaccgtggtggcgttcaac ttcttcaggaagttctacaatagaggggaagagggagagacaccggacatgaagtgtgat gacatgctcacatgttacatgttccacatgtacgtgggcgtgcgggcaggagggggcatc ggtgaccagatcgaggatccagctggtgatgagtatgagatctacaggatcatctttgac atcaccttcttcttcttcgtcatcgtcatcctcctggccatcatccagggtctgataatt gatgcgtttggagaactgagagaccagcaggagcaggtgaaggaggacatggagaccaaa tgcttcatctgcggaataggaaacgactactttgacacagtacctcacggcttcgagact cacaccctgcaggagcacaacttggccaactatctcttttttgtgatgtatctcattaac aaagatgaaacggagcacacgggccaggagtcgtatgtgtggaagatgtaccaggagcgt tgctgggaattcttccctgccggagactgtttccgcaaacaatacgaagaccagctcaac tga

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