Streptomyces flavofungini: QUY26_29700
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Entry
QUY26_29700 CDS
T09698
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfp
Streptomyces flavofungini
Pathway
sfp00300
Lysine biosynthesis
sfp00550
Peptidoglycan biosynthesis
sfp01100
Metabolic pathways
sfp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QUY26_29700 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QUY26_29700 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QUY26_29700 (murF)
Enzymes [BR:
sfp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QUY26_29700 (murF)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DHHA1
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
WJV49319
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Position
6944643..6946070
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AA seq
475 aa
AA seq
DB search
MIALSLAEIATVVGGQTYDIPDPQVQVTAPVVRDSREVQPGGLFAAFVGERVDGHDYAAQ
VVAAGAVAVLGSRPCGAPAIVVDDVPRALGALARHVVARLGATLVALTGSAGKTSTKDLI
AQVIDRKAPTVWTPGSLNNEIGLPLTALSATDETKFLVLEMGARGIGHIRYLTELTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPADGAAILNADDPLVRAMASRTKARVLLF
GESEDADVRAENVRLTENGRPAFTLTTPTGCGDVRLRLYGEHHVSNALAAAAVAHELGMS
VDEIALALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGRAAQAEG
GRTWAVLGHMAELGDDGLAEHDAVGRLAVRLNVNKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAIDLLRSELRPGDVVLVKASRSVGLERVALALLDDAAASEGQVAGR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccaccgtcgtcggcgggcagacgtacgacata
ccggatccgcaggtccaggtgaccgcgccggtcgtccgggactcccgtgaggtgcagccc
ggcggcctgttcgccgctttcgtgggcgagcgcgtcgacgggcacgactacgccgcccag
gtcgtggcggcgggcgcggtcgccgtgctcggctcccggccgtgcggggcgcccgcgatc
gtcgtcgacgacgtgccgagagcgctcggcgccctcgcccggcacgtggtcgcccggctc
ggcgccaccctcgtcgccctcacgggatccgcgggcaagaccagcaccaaggacctgatc
gcccaggtcatcgatcgcaaggcgcccacagtgtggacgccgggctcgctcaacaacgag
atcgggctgccgctgaccgcgctgagcgccaccgacgagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccggtacctgaccgagctgacgccgccgaggatc
ggcctcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gcgcaagcaaagggtgagctggtcgaggcgctcccggccgacggcgccgcgatcctcaac
gccgacgaccccctcgtacgcgcgatggcctcccgcacgaaggcccgggtgctgctcttc
ggcgagtccgaggacgccgacgtacgtgccgagaatgtccggctcacggagaacggccgc
ccggccttcacgctcaccacacccaccgggtgcggggacgtgcggctgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gtggacgagatcgccctcgcgctctccgaggcgggcacgctgtcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcgcggccatgggcagagccgcgcaggccgagggc
gggcgcacgtgggcggtgctcggtcacatggccgagctcggagacgacgggctcgccgag
cacgacgcggtcggacgccttgccgtccggctgaacgtgaacaagctcgtggcagtcggg
ggcagggaagcgtcctggctccaactgggcgcatacaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcgatcgacctgctgcgcagcgagctgcgccca
ggagacgtcgtgctggtgaaggcgtccagatcggtcggtctcgagcgggtcgcgctggcg
ctgctcgatgacgccgccgcttcggaggggcaggtcgccggccgatga
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