Shigella flexneri NCTC1 (serotype 2a): NCTC1_02865
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Entry
NCTC1_02865 CDS
T03751
Symbol
purL
Name
(GenBank) Phosphoribosylformyl-glycineamide synthetase, FGAM synthetase,Phosphoribosylformylglycinamidine synthase,phosphoribosylformylglycinamidine synthase,Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain,phosphoribosylformylglycinamidine synthase,AIR synthase related protein, C-terminal domain
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sft
Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00230
Purine metabolism
sft01100
Metabolic pathways
sft01110
Biosynthesis of secondary metabolites
Module
sft_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sft00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NCTC1_02865 (purL)
Enzymes [BR:
sft01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NCTC1_02865 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
CDX08021
UniProt:
A0A658Y4T7
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All DBs
Position
1:complement(2638249..2642292)
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AA seq
1347 aa
AA seq
DB search
MATYYSHWRHALLIHDGDFISTQTVSSAHQILYNDARFPPLGYTESLEDERLMMEILRGS
PALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKYGPALASH
APQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTNEQWQQVT
AELHDRMMETVFFDLDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLALAEDEID
YLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFRMIKNTFETT
PDHVLSAYKDNAAVMEGSEVGRYFADHETGRYNFHQEPAHILMKVETHNHPTAISPWPGA
ATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTE
GPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKG
EINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRC
WQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQ
ERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGK
TPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQ
MVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQI
GDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEG
NEEREMTSPLSLVISAFARVEDVRHTITPQLCTEDNALLLIDLGKGNNALGATALAQVYR
QLGDKPADVRDVVQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDAD
IASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITA
NGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINED
VAAPYIATGARPKVAVLREQGVNSHVEMAAAFQRGGFDAIDVHMSDLLTGRTGLEDFHAL
VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRELI
PGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDAAH
LAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTV
SNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
4044 nt
NT seq
+upstream
nt +downstream
nt
atggcaacttattacagccattggcggcacgcgttgctaattcacgatggtgattttatt
tccacgcaaacggtttcgtcagcgcatcagattctttataatgacgcccgtttccccccc
cttgggtacaccgaaagcttagaagacgagagacttatgatggaaattctgcgtggttcg
cctgcactgtcggcattccgaatcaacaaactgctggcacgttttcaggctgccaggctc
ccggttcacaatatttacgccgagtatgtccattttgctgacctcaatgcgccgttaaac
gatgatgagcacgcacaacttgaacgcctgctgaaatatggtccggcactcgccagccac
gccccgcaaggcaaactcctgctggtgaccccgcgtcctggcaccatctctccctggtct
tcgaaagcgaccgatattgcccataactgcgggctacaacaggtaaaccgccttgagcgc
ggcgttgcttactatatagaagccggtacgctgaccaatgaacaatggcagcaggttacc
gctgaactgcacgaccgcatgatggaaacggtcttttttgatttagatgatgcagagcag
ttgtttgcccaccatcaaccgactccggtcacaagcgttgatttgctggggcagggccgt
caggcgctgatcgacgctaacctgcgtcttggcttggctctggcggaagatgaaattgac
tatctgcaggatgctttcacaaagcttggtcgtaacccgaacgacatcgagctgtatatg
ttcgctcaggcgaactctgagcactgccgccacaaaatttttaacgccgactggattatc
gacggtgaacaacagccgaaatcgctgttcaggatgatcaaaaatactttcgaaaccacg
ccagatcacgttctctctgcttataaagataacgccgccgtaatggaaggttctgaagtg
ggccgctactttgctgaccacgaaacgggccgctacaatttccatcaggaaccggcgcac
atcctgatgaaagtcgaaactcacaaccacccgacggcgatttctccgtggccgggcgcg
gcgaccggttccggcggtgaaatccgcgatgaaggtgccaccgggcgcggcgcgaagccg
aaagctggtttggttggtttctccgtatccaacctgcgaattcctggcttcgaacagccg
tgggaagaagatttcggtaagcctgagcgcattgttaccgcgctggacatcatgaccgaa
ggcccgctgggcggtgcggcgtttaacaacgaatttggtcgtccggcactgaacggctac
ttccgtacttatgaagaaaaagtgaacagccacaatggcgaagagctgcgcggttatcac
aaaccgatcatgctggcgggcgggatcggcaacattcgcgccgatcacgtacaaaaaggc
gagatcaacgtcggtgcgaagctggtcgttctcggcggcccggcaatgaacatcggtctt
ggcggcggcgcggcgtcttccatggcgtctggtcagtctgatgccgacctcgactttgct
tccgtacagcgcgacaacccggagatggagcgtcgttgccaggaagtgatcgaccgttgc
tggcagcttggtgatgctaacccaattctgtttatccacgacgtcggtgcgggcggtctt
tctaacgcgatgccggagctggtgagcgacggcggacgcggcggtaaatttgaactgcgc
gatattctaagcgacgaaccgggcatgagcccgctggaaatctggtgtaacgaatcccag
gaacgctacgtgctggcggttgctgccgatcaattaccgctgtttgacgaactgtgtaag
cgtgagcgcgcaccctacgcggtgattggtgaagcgaccgaagaactgcatctttctctg
cacgatcgtcattttgataatcagccgatcgatctgccgctggacgtcctgcttggtaaa
acgccgaagatgacccgcgatgtacaaacgctgaaagcgaagggcgatgcgctggtccgt
gaagggatcaccattgcagacgcggtgaaacgcgtactgcatctgccgaccgtggcggag
aaaactttcctggtgaccatcggtgaccgcagcgtaaccggcatggtggcgcgcgatcag
atggtggggccgtggcaggtgccggtcgctaactgcgcggtcactaccgccagcctcgac
agctactacggtgaagcgatggcgattggcgagcgtgcgccggttgcgctgctggatttc
gccgcctctgcccgtctggcggtcggtgaagcgttaaccaatattgccgcaacacagatt
ggcgatatcaaacgcattaaactttccgccaactggatggcggcggcaggccaccctggt
gaagatgcgggcctgtatgaagccgttaaagccgtgggtgaagaactttgtccggcgctg
ggcctgacgatcccggtgggtaaagactctatgtcgatgaaaacccgctggcaggaaggt
aacgaagagcgcgaaatgacgtcgccgctgtcgctggtgatttctgcatttgcccgcgtg
gaagatgtacgtcacaccatcacgccgcagctttgtaccgaagataacgcactgctgctg
attgatttgggcaaaggcaataacgcgctgggcgcaacggcgctggcgcaggtttatcgt
cagcttggcgacaaaccggcagatgtacgcgatgttgtccaactgaaaggcttctatgac
gcgattcaggcgctggttgcacagcgtaagctgctggcgtatcacgaccgctctgatgga
ggcctgctggtaacgctggcggaaatggcctttgcaggtcattgtggcattgacgcggat
atcgcctctctgggtgacgatcgcctggcggcgttgtttaacgaagaactgggtgcggtg
attcaggttcgtgccgctgaccgtgaagcggtcgagtccgtactggcacagcatgggctt
gcggattgcgtccattatgttgggcaggcggtttccggtgaccgttttgtgattaccgcc
aacgggcagactgtattcagcgaaagccgcactacgttgcgtgtctggtgggcagaaact
acctggcagatgcagcgcctgcgtgacaacccggagtgtgccgatcaggagcatcaggcg
aaatctaacgacgccgatccgggcctgaatgtaaaactgtcgttcgatatcaacgaagat
gtggcagcaccgtatattgccactggcgcacgtccgaaagttgccgtactgcgtgagcag
ggcgtgaactcgcatgttgaaatggcggcagctttccaacgtgggggctttgatgctatc
gacgtgcatatgagcgacctgctgactggacgtacgggactggaggattttcacgccctg
gtcgcgtgcggaggtttctcctacggtgatgtgctgggtgccggtgaaggttgggcgaag
tctatcctgttcaatgaccgtgtacgcgatgagtttgcaaccttcttccatcgtccgcaa
acgctggccctgggggtatgtaacggttgccagatgatgtctaacctgcgtgaactgatc
ccggggagtgagttgtggccacgttttgtgcgtaacacctccgatcgctttgaagcgcgt
ttcagcctggttgaagtaacccaaagcccgtctctgctgttgcaggggatggtgggctcg
caaatgccgattgctgtctctcatggtgaagggcgcgtggaagtgcgtgatgcggcgcat
ctggcggcactggaaagcaaagggctggtggcactgcgctatgtcgataacttcggcaaa
gtcactgaaacctacccggctaacccgaacggttcaccgaacggtattacggcggttacg
actgaaagtggtcgagtcaccattatgatgccgcacccggaacgtgttttccgtactgtc
agcaactcctggcatccggaaaactggggcgaggatggcccatggatgcgcattttccgc
aatgcgcgtaagcagttggggtaa
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