KEGG   Shigella flexneri NCTC1 (serotype 2a): NCTC1_02972
Entry
NCTC1_02972       CDS       T03751                                 
Symbol
nrdE
Name
(GenBank) ribonucleotide-diphosphate reductase subunit alpha,Ribonucleoside-diphosphate reductase 2 subunit alpha,ribonucleotide-diphosphate reductase subunit alpha,ribonucleoside-diphosphate reductase, class 1b, alpha subunit,Ribonucleotide reductase, barrel domain
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
sft  Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00230  Purine metabolism
sft00240  Pyrimidine metabolism
sft01100  Metabolic pathways
sft01232  Nucleotide metabolism
Module
sft_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
sft_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:sft00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    NCTC1_02972 (nrdE)
   00240 Pyrimidine metabolism
    NCTC1_02972 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:sft03400]
    NCTC1_02972 (nrdE)
Enzymes [BR:sft01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     NCTC1_02972 (nrdE)
DNA repair and recombination proteins [BR:sft03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    NCTC1_02972 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: CDX08122
UniProt: A0AB33SIA9
LinkDB
Position
1:2738157..2740301
AA seq 714 aa
MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQ
QRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTFLGAWKFYTSYTLKTFDGK
RYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFL
LRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLA
KENAQMALFSPYDVERVYGKPFADIAISEHYDELVADERIRKKYLNARDFFQRLAEIQFE
SGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEYDENLDYARTGHDISCNLGSL
NIAHTMDSPDFSRTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQG
NWQPKTAKVGELFARSCITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATS
SIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQG
LSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
NT seq 2145 nt   +upstreamnt  +downstreamnt
ttggcaacgacaaccgcagaatgcctgacgcaggaaacgatggattaccacgcgctgaat
gcgatgcttaatctttacgatagcgcaggtcgcattcagttcgataaagaccgccaggcc
gttgacgcctttattgcgacgcatgtgcgtccgaacagtgtgaccttcagtagccagcag
cagcgcctgaactggctggtcaacgaaggttactatgatgaaagcgttcttaatcgctac
tctcgcgactttgtcattacgctgtttgcccacgcacacaccagcggttttcgtttccag
acattcctcggggcatggaagttttacaccagctatacgttgaagacattcgacggtaaa
cgttatctggaagattttgccgatcgagtcacgatggtggcgctgacgctggcacaaggc
gatgagacgctggcgttgcaactgaccgatgaaatgctgtcaggacgctttcagccagcc
acgccaacattcctcaactgcggtaagcagcagcgcggcgaactggtttcctgttttttg
ctgcgtattgaagacaatatggagtcgattggtcgggcggtaaattccgcactgcagctg
tcgaaacgcggcggcggcgtagcatttttgctgtcgaatctgcgggaagcgggcgcgcca
attaaacgtattgaaaatcaatcttctggcgtaattccggtgatgaaaatgttggaagac
gcattttcctatgccaaccaactcggcgcgcgtcagggggcaggtgcagtctatttacat
gctcatcatcccgatattctgcgttttctcgacacgaaacgggaaaatgccgacgaaaaa
atccgcattaaaacactgtcgctgggcgtggtgatcccggatatcactttccatctggca
aaagagaatgcgcagatggcgctgttttcgccctatgacgttgagcgagtttatggcaag
ccgtttgccgatatcgccattagcgaacactatgacgaactggttgccgatgaacgcatc
cgcaaaaaatacctcaacgcccgtgatttcttccagcgactggcagaaatccagtttgag
tccggctatccctacatcatgtatgaagacacagtaaaccgtgctaaccctatcgccggg
cgcataaatatgagtaatctctgctcagaaattttgcaggttaacagcgcctcagagtat
gacgagaatctcgactatgcccgcacaggccatgatatttcctgcaatttaggttcgttg
aatattgcgcacaccatggattcccccgatttttcccgcacggtagagactgccgtgcgc
ggtttaacggcggtgtcagatatgagtcatatccgcagcgtgccgtccatcgaagccgga
aatgccgcctcgcacgccatcggactggggcagatgaatttacatggttatctggcgagg
gaaggcatcgcttatggttcgccggaagccctggatttcaccaatctctatttctatacc
atcacctggcacgcactgcgtacctcgatgttgctggcgcgcgaacgcggtgaaaccttc
gccgggttcaaacagtcacgctatgccagtggtgaatatttcagccaatatctgcaaggt
aactggcagccgaaaacggcgaaagttggcgaactgtttgcccgcagctgtattacgtta
cctacccgtgagatgtgggcgcaactgcgcgacgacgtgatgcgctacggcatatacaac
cagaatctccaggcggtgccgccaaccgggtctatctcttatatcaaccatgctacgtcg
agtattcatccgattgtggcgaaagtagagatacgcaaagagggcaaaacaggacgcgtt
tactaccctgccccgtttatgactaacgaaaatctggcgctgtatcaggacgcttacgaa
attggcgcagaaaagatcatcgacacctacgcggaagcgactcgccatgtcgatcagggg
ctgtcgctgacgctgtttttccccgataccgccaccactcgcgatatcaacaaagcgcag
atttacgcctggcgcaaaggtatcaaaacgctctattacatccgcctgcgtcagatggcg
ctggaaggcactgaaattgaaggctgcgtctcctgtgcactttaa

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