Shigella flexneri NCTC1 (serotype 2a): NCTC1_04426
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Entry
NCTC1_04426 CDS
T03751
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase,Bifunctional purine biosynthesis protein PurH,bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase,Folate-dependent phosphoribosylglycinamide formyltransferase PurN,phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase,AICARFT/IMPCHase bienzyme
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sft
Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00230
Purine metabolism
sft00670
One carbon pool by folate
sft01100
Metabolic pathways
sft01110
Biosynthesis of secondary metabolites
Module
sft_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sft00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NCTC1_04426 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCTC1_04426 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sft04147
]
NCTC1_04426 (purH)
Enzymes [BR:
sft01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
NCTC1_04426 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
NCTC1_04426 (purH)
Exosome [BR:
sft04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
NCTC1_04426 (purH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
NSP2_assoc
Motif
Other DBs
NCBI-ProteinID:
CDX09496
UniProt:
A0A6D2VYA5
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All DBs
Position
1:complement(4141460..4143049)
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AA seq
529 aa
AA seq
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MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFC
WKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFP
FRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaagccggtatc
gtcgaattcgcccaggcactttccgcacgcggtgtggagctgctgtctacagggggcact
gcccgtctgttagcagaaaaaggtctgccggtaaccgaagtttccgattacaccggtttc
ccggagatgatggatggacgcgtgaagaccctgcatccgaaagtacatggtggcattctg
ggccgtcgcggccaggacgatgccattatggaagaacatcagatccagcctatcgatatg
gtggttgttaacctgtatccgttcgcccagactgttgctcgtgaaggctgctcgctggaa
gatgcggttgagaacatcgatatcggcggcccgaccatggtgcgctccgccgctaagaac
cataaagatgtcgcaatcgtggtgaagagcagcgactacgacgccattattaaagagatg
gatgacaacgaaggatcgctgacgcttgcaacccgtttcgacctcgccatcaaagccttc
gaacacactgccgcctacgacagcatgattgccaactacttcggcagcatggttccggcg
taccacggtgaaagcaaagaagccgccggtcgcttcccacgcacgctgaacctgaacttc
attaagaagcaggatatgcgttacggcgagaacagccaccagcaggctgccttctatata
gaagagaatgtgaaagaagcctccgttgctaccgcaacccaggttcagggtaaagccctc
tcttataacaacatcgccgataccgatgcggcgctggagtgcgtgaaagagttcgccgag
ccggcatgtgtgattgtgaagcacgccaacccttgcggtgtagctatcggcaattccatt
cttgatgcttacgatcgcgcgtacaaaaccgacccaacctccgcattcggcggcatcatt
gcctttaaccgcgagctggatgcggaaaccgcacaggccatcatttctcgtcagtttgtc
gaagtgattattgcgccttccgccagcgaagaagccctgaaaatcaccgccgccaagcag
aacgtacgcgttctgacctgcggtcagtggggcgagcgtgttccgggtcttgatttcaaa
cgcgtgaacggcggtctgctggttcaggatcgtgacctggggatggtcggtgcggaagaa
ctgcgcgtcgtcacccaacgtcagccgaccgaacaggaactgcgtgatgcgctgttctgc
tggaaagtggcgaaattcgtgaaatccaatgctatcgtctatgccaaaaacaatatgacc
atcggtattggcgcgggccagatgagccgcgtgtactccgcgaaaatcgccggtattaaa
gctgccgatgaaggcctggaagtgaaaggttcctcgatggcttctgacgcgttcttcccg
ttccgcgacggtattgatgccgccgccgctgcgggcgtgacctgcgtaatccagcctggc
ggttccatccgtgatgacgaagtgattgccgccgccgacgagcacggtattgcgatgctc
ttcaccgacatgcgccacttccgccattaa
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