Streptomyces fungicidicus: CNQ36_09285
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Entry
CNQ36_09285 CDS
T07133
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfug
Streptomyces fungicidicus
Pathway
sfug00300
Lysine biosynthesis
sfug00550
Peptidoglycan biosynthesis
sfug01100
Metabolic pathways
sfug01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfug00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CNQ36_09285
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CNQ36_09285
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CNQ36_09285
Enzymes [BR:
sfug01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CNQ36_09285
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
RPAP1_N
Motif
Other DBs
NCBI-ProteinID:
AYL35611
UniProt:
A0A494UYH3
LinkDB
All DBs
Position
complement(2057465..2058880)
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AA seq
471 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQVTGPVVRDSREAGPGSLFVAFVGERVDGHDFAAR
VVGAGAVAVLASRPVGVPAIVVEDVQAALGALARYVVGRLGTTLVALTGSAGKTSTKDLI
AQVLQRAAPTVFTPGSLNNEIGLPLTALTATEETKFLVLEMGARGIGHIRYLTGLTPPKV
GLVLNVGSAHIGEFGGREQIAQAKGELVESLPPAEEGGAAVLNADDPLVRAMASRTKAKV
ILFGESGEADVRAENVRLTDSGQPSFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIARALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMKAALRALVAMGKGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREAAWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALLETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggacccgtccgtccaggtcaccggaccggtcgtcagggactcgcgggaggcgggtccg
ggcagcctgttcgtcgccttcgtcggcgagcgcgtggacggccacgacttcgcggcccgg
gtcgtcggggcgggcgcggtcgccgtgctcgcctcgcggcccgtgggggtgcccgcgatc
gtcgtggaggacgtccaggcggccctcggggccctcgcccggtacgtcgtcggcaggctc
gggaccacgctcgtcgcgctcaccggctcggccggcaagaccagcaccaaggacctcatc
gcgcaggtcctgcagcgggccgcgccgaccgtcttcacccccggctcgctcaacaacgag
atcgggctgccgctcaccgcgctcaccgccaccgaggagacgaagttcctcgtgctggag
atgggagcgcgcggaatcggccacatccgctacctcaccggtctgaccccgccgaaggtc
ggcctggtcctgaacgtcggctccgcccacatcggcgagttcggcggccgggagcagatc
gcccaggccaagggcgagttggtggagtcgctgccgccggccgaggagggcggcgccgcg
gtcctcaacgcggacgaccccctcgtaagggccatggcgtcccgtacgaaggcgaaggtg
atccttttcggagagtccggcgaagcggacgttcgggccgagaacgtgcgactcacggac
agcggacagccttccttcaggcttcacacaccctccggtgcatccgatgtgaccatgcgc
ctgtacggtgagcatcacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgcccgcgcgctctccgaggcgggctccctctcccgctgg
cgcatggaggtcaccgagcggccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgaatccatgaaggcagcgctgcgcgcgctggtggccatgggcaaggggcgtcgt
acgtgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagg
gaagccgcctggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgaattgcgcccgggggat
gtcgtactcgtgaaggcatcccgttcggtcgggctcgagagcgtggcgcaggcgctgctc
gagaccggtgccgagggtgaggtcgccgcccgatga
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