Sorex fumeus (smoky shrew): 130016518
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Entry
130016518 CDS
T10594
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04020
Calcium signaling pathway
sfum04022
cGMP-PKG signaling pathway
sfum04024
cAMP signaling pathway
sfum04148
Efferocytosis
sfum04260
Cardiac muscle contraction
sfum04261
Adrenergic signaling in cardiomyocytes
sfum04380
Osteoclast differentiation
sfum04919
Thyroid hormone signaling pathway
sfum04972
Pancreatic secretion
sfum05010
Alzheimer disease
sfum05017
Spinocerebellar ataxia
sfum05022
Pathways of neurodegeneration - multiple diseases
sfum05410
Hypertrophic cardiomyopathy
sfum05412
Arrhythmogenic right ventricular cardiomyopathy
sfum05414
Dilated cardiomyopathy
sfum05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
130016518 (ATP2A2)
04024 cAMP signaling pathway
130016518 (ATP2A2)
04022 cGMP-PKG signaling pathway
130016518 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
130016518 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
130016518 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
130016518 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
130016518 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
130016518 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
130016518 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
130016518 (ATP2A2)
05017 Spinocerebellar ataxia
130016518 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
130016518 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
130016518 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
130016518 (ATP2A2)
05414 Dilated cardiomyopathy
130016518 (ATP2A2)
05415 Diabetic cardiomyopathy
130016518 (ATP2A2)
Enzymes [BR:
sfum01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
130016518 (ATP2A2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
130016518
NCBI-ProteinID:
XP_055963215
LinkDB
All DBs
Position
Unknown
AA seq
998 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPLTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQEEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEQPAILE
NT seq
2997 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagaagtggggctccaacgag
ctgccggctgaggaagggaaaaccttgctggaacttgtgatcgagcagttcgaagaccta
ctcgtgagaattttattgctggcagcgtgtatatcttttgttttggcttggtttgaagaa
ggcgaagaaacaattacagcctttgtggaacccttcgtaatcttacttatattggtagcc
aacgccattgtgggtgtgtggcaggaaagaaatgctgaaaatgccattgaagcccttaag
gagtatgagccagaaatgggcaaagtgtatcggcaggacagaaagagcgtacaacgaatc
aaagctaaagacatagttcctggggacattgtagagattgctgttggtgacaaagttcct
gctgatatcagattaacttcaatcaaatctactactctaagagttgatcagtccatcctc
acaggtgaatcagtctccgtcatcaagcacactgaccctgtccctgatccacgtgctgtc
aaccaggacaaaaagaacatgctcttctctgggacaaacattgctgccggcaaagccatg
ggcgtggtggtggcaaccggggttaacactgaaatcggcaagattcgggatgagatggtg
gccacagaacaggagagaacacccctccagcagaaactggatgagttcggggagcagctg
tccaaagtcatctccctcatttgcattgccgtctggatcataaacatcggccacttcaat
gacccggttcacggcggctcctggatcagaggcgctatttactacttcaaaatcgctgtg
gccctggccgtagcggccattcccgaaggactgcctgccgtcatcaccacctgccttgct
ctgggaactcgaagaatggcaaagaaaaatgcgattgttcgcagtctcccttccgtggaa
actcttggttgtacttccgtcatctgctcagataagactggtactcttacgacaaaccag
atgtcggtctgcaggatgttcatcctggacaaagttgaaggtgatacttgctcccttaat
gagtttacaataacggggtcaacttacgcacctattggagaagtgcataaagatgataag
ccagtgaaatgtcatcaatatgatggtcttgtagagttggcaacaatttgtgctctttgt
aatgactctgcgctggattacaatgaggcaaaaggtgtgtatgaaaaagttggagaagca
acggagactgccctcacttgcctggtagagaagatgaatgtatttgatactgaattgaaa
ggtctctctaaaatagaacgcgcaaacgcctgcaactcggtcattaaacagttgatgaaa
aaagaattcacgctcgagttttcacgtgacagaaagtccatgtcagtttactgtacaccg
aacaaaccaagccggacatcaatgagcaaaatgtttgtgaagggtgctcctgagggcgtg
attgacaggtgcacccacatccgagttggaagcactaaagtccctttgacccctggggtc
aaacagaagatcatgtctgtcatccgggaatgggggagtggcagcgacaccctgcggtgc
ctggcactggcgactcatgacaatccactgagaagagaagagatgaaccttgaggactct
gccaacttcattaaatatgagaccaatctgactttcgttggctgcgtgggcatgctggac
cccccaagaattgaagtggcttcttctgtaaaactgtgccgacaagcaggtatccgggtc
atcatgatcacaggggacaataagggcactgcagtagccatctgtcgccgcattggcatc
tttgggcaagaagaggatgtgacatcaaaagcttttaccggacgagagtttgatgagctc
agtccatcagcacagagagatgcctgcttgaatgcccgttgtttcgctcgtgtggagcca
tctcacaagtctaaaattgtagaatttcttcagtctttcgatgagatcacagctatgact
ggagacggtgtcaatgatgcgcctgctctgaagaaatcggagatcggcatcgccatgggc
tctggtactgcagtagccaaaactgcatcagagatggtgcttgcggatgacaacttctcc
accatcgtggctgctgttgaggaggggcgggcaatctataacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggggaagttgtctgtattttcctgacagcggccctt
ggctttcctgaggctttaattcctgtccagctgctttgggtcaatctggtgacagatggc
ctgcctgccactgcattggggttcaaccctcccgatctagacatcatgaataaaccaccc
aggaacccaaaggaaccactgatcagcgggtggctcttcttccgttacctggctattggc
tgttatgttggcgctgctactgtgggtgctgctgcctggtggttcattgctgccgatggt
ggtccaagagtgtccttctaccagctgagtcatttcctacagtgtaaagaggacaatccg
gactttgaaggcgtggattgtgcaatctttgagtctccatacccaatgacaatggcgctc
tctgtgctagtaaccatagagatgtgtaacgcactcaacagcttgtctgaaaaccagtcc
ctgctaaggatgcctccttgggagaatatctggctcgtgggctccatctgcttgtccatg
tcactccacttcctgatcctctacgtggagcccttgccccttatcttccagatcacacca
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctgatggat
gagacactcaagtttgtggcccgcaactatctggaacaacctgcaatactggagtaa
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