KEGG   Sorex fumeus (smoky shrew): 130016670
Entry
130016670         CDS       T10594                                 
Symbol
GRIN2A
Name
(RefSeq) glutamate receptor ionotropic, NMDA 2A
  KO
K05209  glutamate receptor ionotropic, NMDA 2A
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04014  Ras signaling pathway
sfum04015  Rap1 signaling pathway
sfum04020  Calcium signaling pathway
sfum04024  cAMP signaling pathway
sfum04080  Neuroactive ligand-receptor interaction
sfum04082  Neuroactive ligand signaling
sfum04713  Circadian entrainment
sfum04720  Long-term potentiation
sfum04724  Glutamatergic synapse
sfum04728  Dopaminergic synapse
sfum05010  Alzheimer disease
sfum05014  Amyotrophic lateral sclerosis
sfum05017  Spinocerebellar ataxia
sfum05020  Prion disease
sfum05022  Pathways of neurodegeneration - multiple diseases
sfum05030  Cocaine addiction
sfum05031  Amphetamine addiction
sfum05033  Nicotine addiction
sfum05034  Alcoholism
sfum05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    130016670 (GRIN2A)
   04015 Rap1 signaling pathway
    130016670 (GRIN2A)
   04020 Calcium signaling pathway
    130016670 (GRIN2A)
   04024 cAMP signaling pathway
    130016670 (GRIN2A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    130016670 (GRIN2A)
   04082 Neuroactive ligand signaling
    130016670 (GRIN2A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    130016670 (GRIN2A)
   04728 Dopaminergic synapse
    130016670 (GRIN2A)
   04720 Long-term potentiation
    130016670 (GRIN2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    130016670 (GRIN2A)
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    130016670 (GRIN2A)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    130016670 (GRIN2A)
   05014 Amyotrophic lateral sclerosis
    130016670 (GRIN2A)
   05017 Spinocerebellar ataxia
    130016670 (GRIN2A)
   05020 Prion disease
    130016670 (GRIN2A)
   05022 Pathways of neurodegeneration - multiple diseases
    130016670 (GRIN2A)
  09165 Substance dependence
   05030 Cocaine addiction
    130016670 (GRIN2A)
   05031 Amphetamine addiction
    130016670 (GRIN2A)
   05033 Nicotine addiction
    130016670 (GRIN2A)
   05034 Alcoholism
    130016670 (GRIN2A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:sfum04040]
    130016670 (GRIN2A)
Ion channels [BR:sfum04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   130016670 (GRIN2A)
SSDB
Motif
Pfam: NMDAR2_C Lig_chan Lig_chan-Glu_bd ANF_receptor SBP_bac_3 DUF6410
Other DBs
NCBI-GeneID: 130016670
NCBI-ProteinID: XP_055963378
LinkDB
Position
Unknown
AA seq 1468 aa
MGRLGYWALLGLAALLVWRGPAPAAAAEKGPPALNIAVLLGHSHDMTERQLRTLWGPEQG
AGLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSQT
FVPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHTFSLVTTIFPGY
REFISFVKTTVDNSFVGWDVQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVAIL
SEARALGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGLGILT
TAAASMLEKFSYIPEAKASCYGQSDKPEAPQHTLHQFMVDVTWNGKDLSFTEDGYQVHPR
LVVIVLNKDREWEKVGKWENQSLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVE
DIDPLTETCVRNTVPCRKFVRINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLV
TNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRS
NGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFT
IGKAIWLLWGLVFNNSVPVQNPRGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVD
QVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSL
KSGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALL
QFVGDGEMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHL
FYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEDKKKSPDFSGSQSNVLKLLRSAK
SMSNAPHANPPRMDSPQGTADFIPRGSLIMDMVPDKGNPIYADPRSFQGKDGFFGDSMNE
LQTFVANRHKDSLNNYVFPGQHPLTLNETNPNTVEVAVSTDAKGSSRPRQLWKKSMESLR
QDSLSQNPACPREDGPGENRSHSLKSPRYLPEELAHSDISEASSRATAYREPDNSKNHKT
KDNFKRSLASKYPKEGSEATERGSFLKTKASSPRDKIYTIDGEKEPSFHLDPPQLVDNLS
VPESFPDPYADVGENYRKGDATLPLTRNAQPSGGGDGSSSLPNNDHYKLYSKHLTLKDTS
SPHSEGSERYRSNSTHCRSCLSHLPTYAGHFTVRSPFKCDACLRLGNLYDIDEDQMLQDT
GHRASPDEAYSQDWAQNNALQLQKNKLHISRQRSHDNILDKAREADAVGRASRSVSLKDR
ERLLEGNLYGSLFSVPSSKLLGNKSSLFPQGLEDSKRSKSLLPDHASDNPFLHSYGNDHR
LVIGRCPSDPYKHSLPSQAMSDSYLRSSLRSTASYCSRDSRGHGDVYISEHVLPYAANKN
NLYSTPRVMNSCSNRRVYKKMPSIESDV
NT seq 4407 nt   +upstreamnt  +downstreamnt
atgggcagactgggctactgggcgctgctgggactggcggcccttctggtgtggcgcggc
ccggcgcccgcggcggcggccgagaaggggcctccggcgctgaacatcgcggtgctcctg
ggccacagccacgacatgacggagcgccagctgcggacgctgtgggggcccgagcagggc
gcggggctgcccctcgacgtgaacgtggtggcgctgctgatgaaccgcaccgaccccaag
agcctcatcacgcacgtgtgcgacctcatgtcgggcgcccgcatccacggcctggtgttc
ggggacgacacggaccaggaggccgtggcgcagatgctggattttatctcctcgcagacg
ttcgtgcccatcctgggcatccacgggggcgcgtccatgatcatggctgacaaggaccca
acatccaccttctttcagttcggtgcgtccatccagcagcaggccacagtcatgctgaag
atcatgcaggactacgactggcacaccttctcgctggtcaccaccatcttccccggctac
cgggagttcatcagcttcgtcaagaccacggtggacaacagcttcgtgggctgggacgtg
cagaacgtcatcaccctggacacatccttcgaggatgccaagacgcaggtgcagctgaag
aagattcactcgtcagtaatcctgctctactgttccaaggacgaggccgtggccatcctg
agcgaggcgcgggcgctcggcctcacaggctacgactttttttggatcgtgcccagcctg
gtgtcgggcaacacggagctcatccccaaggagttcccctcaggcctcatctccgtgtcc
tatgacgactgggactacagcctggaggcccgggtccgggatggcctgggcatcctcacc
acggccgccgcgtccatgctggagaagttctcctacatcccagaggccaaggccagctgc
tatgggcagtcagacaagccagaagcccctcagcacacactgcaccagttcatggtggac
gtgacgtggaacggcaaagacctgtccttcaccgaggacggctaccaggtgcacccccga
ctggtggtcatcgtgctgaacaaggaccgggagtgggagaaggtgggcaagtgggagaac
cagagcttgagcctgaggcatgccgtgtggccgcgctacaagtccttctcggactgcgag
cccgacgacaaccacctgagcattgtcaccctggaggaggccccgttcgtcatcgtggaa
gacatcgacccgctcaccgagacctgcgtcaggaacacggtgccctgccgcaagttcgtc
aggatcaacaactcaaccaatgagggaatgaacgtcaagaagtgctgcaagggcttctgc
attgacatcctcaagaagctctccaggaccgtgaagttcacctatgacctctacctggtg
accaatgggaagcacggcaagaaagtgaacaacgtgtggaacggcatgatcggggaagtg
gtctaccagcgggcggtcatggccgtgggctcactcaccatcaacgaggagcgctcggag
gtggtggacttctccgtaccctttgtggaaacgggcatcagcgtcatggtctccaggagc
aacgggactgtctccccctccgcgtttctagagcccttcagcgcctccgtctgggtgatg
atgttcgtcatgcttctcatcgtctccgccatcgccgtctttgtcttcgaatacttcagc
ccggtcgggtacaacaggaacttggccaaagggaaagcaccccacgggccgtcgttcacc
atcgggaaggccatctggctgctctgggggctggtgttcaacaactccgtgcccgtgcag
aacccccgggggaccacgtccaagatcatggtgtccgtgtgggccttcttcgccgtcatc
ttcctggccagctacacagccaacctggccgccttcatgatccaggaggagttcgtggac
caggtgacagggctcagtgacaagaagttccagcgccctcacgactactccccaccattt
cggtttggaacggtgcccaacggcagcacagagagaaacatccgcaacaattacccctac
atgcaccagtacatgaccaagttcaaccagaagggcgtggaggacgccttggtcagcctg
aaatctgggaagctggacgccttcatctacgacgcggccgtgctgaactacaaggcaggc
cgggacgagggctgcaagctggtgaccatcggcagcggctacatctttgccaccacgggc
tacgggattgccctgcagaaggggtccccctggaagaggcagattgacctggcgctgctc
cagtttgtgggtgacggggagatggaggagctggagactctgtggctcacgggcatctgc
cacaacgagaagaatgaggtcatgagcagccagctggacattgacaacatggcgggtgtg
ttctacatgctggcagccgccatggccctcagcctcatcaccttcgtctgggagcacctc
ttctactggaagctgcgcttctgcttcaccggcgtgtgctccgaccgcccagggctgctc
ttctccatcagcaggggcatctacagctgcatccacggggtgcacatcgaggataagaag
aagtcccccgacttcagtggctcccagagcaacgtgctaaagctgctgcgctcagccaag
agcatgtccaatgctccccacgcgaaccccccgcgcatggactccccgcagggcacagcc
gacttcatcccccggggctccctcatcatggacatggtccccgacaagggcaaccccatc
tatgccgacccccgctccttccagggcaaggacggcttcttcggcgacagcatgaacgag
ctgcagacgttcgtggccaaccggcacaaggacagcctcaacaactacgtgttcccgggc
cagcacccgctgacgctcaacgagaccaaccccaacacagtggaggtggccgtgagcacg
gacgccaagggcagctcccggccgcggcagctctggaagaaatccatggagtccctgcgc
caggactccctgagccagaacccggcgtgcccgcgggaggacgggcccggcgagaaccgc
agccactcgctcaagagcccgcgctacctgcccgaggagctggcccactcggacatctcc
gaagcgtccagccgggccacggcctaccgggagccggacaacagcaagaaccacaagacc
aaggacaacttcaaaaggtcactggcctccaagtaccccaaggagggcagtgaggccacg
gagcgcggctccttcttgaaaaccaaagccagctcgccccgggacaagatctacaccatc
gatggcgagaaggagcccagcttccacctggaccccccgcagctggtggacaacctctct
gtgcccgagagtttcccggatccctacgcggacgttggcgagaactaccgcaagggtgac
gccacgctgcccctcacccggaacgcgcagcccagcggcggcggcgacggaagcagcagc
ctgcccaacaatgatcactacaagctctactccaagcacctcaccctgaaggacacgagc
tccccacacagcgagggcagcgagcgctaccgctccaactccacccactgccggagctgc
ctgtcccacctgcccacctacgccggccacttcaccgtgcgctcccccttcaagtgtgac
gcctgcctccgcctgggcaacctctacgacatcgacgaggaccagatgctgcaggacacg
ggccaccgggccagccccgacgaggcctactcgcaggactgggcccagaacaacgccctc
cagctgcagaagaacaagctgcacatcagccggcagcgttcacacgacaacatcctcgac
aaggcccgggaggctgatgccgtcggccgggccagccgcagcgtcagcctcaaggaccgg
gagcggctgctggaggggaacctgtacggaagcctcttcagcgtcccctccagcaaactc
ttgggcaacaagagctccctcttcccccagggcctggaggacagcaagcggagcaagtcg
ctcctgcccgaccacgcctccgacaaccctttcctccactcctacgggaacgaccaccgc
ctggtgatcgggaggtgcccctcagacccctacaaacactccctgccctcgcaggccatg
agcgacagctacctgcgctcgtccctgcggtccacggcctcgtactgctcccgggacagc
cggggccacggcgacgtgtacatttccgagcatgttctgccttacgctgcaaataagaat
aatctgtactcgacccccagggttatgaattcctgcagcaatagacgtgtgtacaagaaa
atgcctagtatcgaatccgacgtttag

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