Sorex fumeus (smoky shrew): 130017985
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Entry
130017985 CDS
T10594
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum00790
Folate biosynthesis
sfum01100
Metabolic pathways
sfum01240
Biosynthesis of cofactors
sfum01523
Antifolate resistance
sfum04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
130017985 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
130017985 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
130017985 (FPGS)
Enzymes [BR:
sfum01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
130017985 (FPGS)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
130017985
NCBI-ProteinID:
XP_055964765
LinkDB
All DBs
Position
Unknown
AA seq
590 aa
AA seq
DB search
MSRAHGHLLAALSLAGLSPRGARSGAAARRGWSAWPAPQQPDMEYQEAVRMLNTLQTNAS
YLEQVKHQRGDPQTQLEAMELYLARSGLQVEDLEQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTRHFWHLYHRLEETKDSSSCLSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTLEKI
AWQKGGIFKPGVPAFTVAQPDSPLAVLRDRAQQISCPLYVCPPLEALEEGGPPLALGLEG
DHQRSNAALALQLARCWLQRQRDQQDVGEPKESGPPLLQQLPLAPVFRPTPHMRLGLRET
EWPGRTQVLCRGPLTWYLDGAHTSSSVLACTRWFKQALQSRKRQGSGPEVRVLLFNSTGD
RDPAALLKLLQPCHFDYAVFCPNLTEVSSTGNADQQNFMVTLDQVLLRCLEHQQLWGRLA
EEQSGLHLWDPPAEPEPSGPAPLRLASRPPPAPRPSSLVFSCISHALQWISQGRDPVFQL
PGAPQSLLTHPVANSGASVLREAAAVHVLVTGSLHLVGGVLKLLQPSMSQ
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcccacggccacctgctcgcggcgctgtccctggcggggctctcaccgcgc
ggcgcaaggagcggggcggcggcgcggcgcggctggagcgcgtggcccgcgccgcagcaa
ccggacatggagtatcaggaggcggtgcgcatgctcaacaccctgcagaccaatgccagc
tacctggagcaggtgaagcaccagcggggagacccccagacgcagctggaggccatggag
ctctacctggcccggagcgggctgcaggtggaggacctggagcagctgaacatcatccac
gtcaccgggaccaagggaaagggttctacctgtgccttcaccgaacgcatcctccggagc
tatggcctgaagacaggattcttcagctctccgcacctggtgcaggtacgtgagcggatc
cgcatcaacgggcagcccatcagccccgagctcttcaccagacacttctggcacctctac
caccgcctcgaggagaccaaggacagcagcagctgcctgtccatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagaaaaggtagacctggccgtggtg
gaggtgggcatcggcggggcgtacgactgcaccaacatcatcaggaagcctgtggtgtgc
ggggtctcctcgctgggcatcgaccacaccagccttctgggggacacgctggagaagatc
gcgtggcagaaagggggcatcttcaagcctggtgtgcctgccttcactgtggcccagcct
gacagccccctggccgtgctgagggaccgcgcacagcagatctcttgtcctctctacgtg
tgtccaccactggaagcgctggaggagggcgggccgccgctggccctgggcctggagggg
gaccaccagcgctccaacgccgccttggccctgcagttggcgcggtgttggctgcagcgg
cagcgggaccagcaggacgtcggagagccgaaggagtccgggccgcccctcctgcagcag
ctgcctctggcgcctgtgttccggcccacgccccacatgcggcttgggcttcgggaaacg
gagtggcctggccggacgcaggtgctgtgccgtggaccgctcacctggtacctggacggt
gcgcacacctcgagcagcgtgctggcctgcacccgctggtttaagcaggcgctgcaaagt
cgcaagaggcagggcagcgggcccgaagtgcgagtcttgctcttcaactccactggcgac
agggatcccgcggccctgctgaagctgctgcagccctgccattttgactatgccgtgttc
tgcccgaacctgaccgaggtgtcatccacaggcaatgcggatcagcagaacttcatggtg
acgctggaccaggtgctgctccgctgccttgaacaccagcagctctggggccgcctggct
gaggagcagagcggcctgcacctctgggacccccccgcagagccggagcccagcgggccc
gcccccctgcggctggcctcccggccaccccccgccccccggcccagctccctggtcttc
agctgcatctcgcacgccttgcagtggatcagccaaggccgggatcctgtgttccagctg
cccggtgccccccagagcctcctgacgcaccctgtggccaacagcggggccagtgtgctg
cgggaggccgcggccgtccacgtgctggtcaccggcagcctgcatctggtgggcggcgtg
ctcaagctgctgcagccaagcatgtcccagtag
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