| Entry |
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| Symbol |
PDGFRA
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| Name |
(RefSeq) platelet-derived growth factor receptor alpha
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| KO |
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| Organism |
sfum Sorex fumeus (smoky shrew)
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| Pathway |
| sfum01521 | EGFR tyrosine kinase inhibitor resistance |
| sfum05230 | Central carbon metabolism in cancer |
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| Brite |
KEGG Orthology (KO) [BR:sfum00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
130020701 (PDGFRA)
04014 Ras signaling pathway
130020701 (PDGFRA)
04015 Rap1 signaling pathway
130020701 (PDGFRA)
04630 JAK-STAT signaling pathway
130020701 (PDGFRA)
04020 Calcium signaling pathway
130020701 (PDGFRA)
04072 Phospholipase D signaling pathway
130020701 (PDGFRA)
04151 PI3K-Akt signaling pathway
130020701 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
130020701 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
130020701 (PDGFRA)
04540 Gap junction
130020701 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
130020701 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
130020701 (PDGFRA)
05206 MicroRNAs in cancer
130020701 (PDGFRA)
05230 Central carbon metabolism in cancer
130020701 (PDGFRA)
05231 Choline metabolism in cancer
130020701 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
130020701 (PDGFRA)
05218 Melanoma
130020701 (PDGFRA)
05215 Prostate cancer
130020701 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
130020701 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
130020701 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:sfum01001]
130020701 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:sfum04090]
130020701 (PDGFRA)
Enzymes [BR:sfum01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
130020701 (PDGFRA)
Protein kinases [BR:sfum01001]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
130020701 (PDGFRA)
CD molecules [BR:sfum04090]
Proteins
130020701 (PDGFRA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1096 aa
MGTDHRTFLLLGCLLTGLRLPAAQLSFPSILPNENEKVVRLNSSFSLRCLGESEVNWLYP
TAEDENSNVEIRNEETNSGLFVKVLEVANASAAHTGLYTCYYNHTQTLDESDVEGRHIYI
YVPDPDVAFVPLGLTDSLVIVDEDGTSIIPCRTTDPDTPVTLLNNEGVVPAIYDSRQGFN
GTFPGGTYVCEATIRGKPVRTLSFTVYALKATPELELEMKALQTVYKAGETVEVTCVVFN
NEVVDLKWTYPGQVKGKGNIMLEEIKYPIIKLTYTLKVQEATVKDSGDYECAAGHATKEV
KEMKKVTISVHEKGFVEITPNFSQLETVNLHEVKNFVVDVEAYPPPRISWLKDNLTLIEN
LTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIIVQNEDDVKSYTFELLTQVPASIQD
LVDDHHGSTGGQTVRCTAGGTPLPDIEWMICKDIKKCNNETSWTVLTNNVSNLIMESQPR
DRNTVEGRVTFTKVEETIAVRCLAKNLLGSENRELKLVASTLRSELTVAAAVLVLLVIVI
ISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRS
YVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVK
NLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGM
MVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGHYK
KSYEKIHLDFLKSDHPAVARMRADSDHAYIGVPYKNEEDKLKDWEGGLDEQRLSADSGYI
IPLPDIDPVPEEEEEEEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMM
DDIGIDSSDLVEDSFL |
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| NT seq |
3291 nt +upstreamnt +downstreamnt
atgggcactgaccaccggactttcctgcttctaggctgtctcctcacaggcctgcgcctc
cccgccgctcagctgtccttcccctccatcctccccaacgagaacgagaaggtggtgcgg
ctgaattcgtccttctctctgcgctgcctgggggagagcgaagtgaactggctgtacccg
acggccgaggacgagaactccaacgtggagatcaggaacgaggagaccaacagcggcctg
ttcgtgaaggtgctggaagtggccaacgcctcggccgcccacacggggctgtacacctgc
tactacaaccacacgcagaccttggacgagagcgacgtcgaaggccgccacatctacatc
tacgtgccagacccggatgtagccttcgtaccactaggactgacagattctttagtcatc
gtggatgaagatggcacttccatcataccttgccgcacaacggatccggacactcctgtc
accttactcaacaatgagggggtggtccctgccatctatgatagcagacaaggctttaat
ggcacctttcctggcgggacctacgtctgtgaggccactatccgaggcaagcccgtccgg
accctctcatttactgtttatgctttaaaagccacaccagagctggagctcgagatgaaa
gctctgcagacggtctacaaggcaggggagacggtggaagtgacctgcgtcgtctttaac
aacgaggtggtcgacctgaagtggacttaccctgggcaagtgaaaggcaaaggaaacatc
atgctagaggaaatcaaatatccaatcatcaaattgacgtacactctgaaggtccaggag
gccacggtgaaagatagtggagattatgaatgtgctgccggccacgccaccaaggaagtc
aaagaaatgaagaaagtcaccatttctgtccacgagaaaggcttcgtggaaatcacgccc
aacttcagccagttggaaactgtcaacttgcatgaagtcaagaattttgtggtggacgtt
gaggcctaccctccccccaggatctcctggctcaaagacaacctgactctgatagaaaac
ctcacggagatcaccacagatgtagaaaagatccaggaaataaggtatcgaagcaaatta
aagctgatccgtgctaaggaagaagacagtggccactacacgatcatagttcagaatgaa
gatgatgtgaagagctatacttttgaactcttaactcaagttcctgcatctattcaggac
ctggttgacgaccaccacggctccacagggggacagactgtgaggtgcacagccggaggg
acgcctcttcctgacattgagtggatgatttgcaaggatattaagaaatgtaacaacgag
acttcgtggacagttttgaccaacaacgtctcaaacctcattatggagagccagccccga
gacaggaatacagtggaaggcagagtgacttttaccaaagtcgaggagaccatcgctgtg
cgctgcttggctaaaaatctccttggatctgagaaccgagagctgaagctggtggcttcc
acgctgcgttccgaactcactgtggccgctgcagtcctggtgctcttggtgattgtgatc
atctcacttattgtcctggttgtcatttggaagcagaaacccaggtatgagattcgttgg
cgggttatcgaatctatcagcccagatggacacgaatatatctatgtggacccaatgcag
ctgccttatgactcgagatgggagttcccaagagatggactggttcttggtcggatcctg
ggatctggtgcctttggaaaagtggttgaaggaactgcctatggattaagccggtcccag
cctgtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagtgaaaagcaa
gctctcatgtcagaattgaaaataatgactcacttgggaccacacttaaatattgtcaac
ttgctgggagcctgtaccaagtcaggccccatttacatcattactgagtactgcttctat
ggggatctggtcaactatttgcataagaatagggacagcttcctcagccgccacccagag
aagccaaagaaagagctggacatctttggattaaaccctgctgatgaaagcacacgaagt
tacgtcattttatcttttgaaaacaacggtgactacatggacatgaagcaggcagacacc
acgcagtatgtgcccatgctggagaggaaggaggtgtctaagtactcggacattcagaga
tccctgtatgaccgcccggcctcctacaagaagaagtctatgttagactcagaagtcaaa
aacctcctttcggatgataattcagaaggcctcactctgttggatttgttgagctttacc
tatcaagttgcccgaggaatggaatttttggcctcaaaaaactgtgtccaccgggacttg
gctgctcgcaacgttctccttgctcaagggaaaattgtaaagatctgtgactttggcctg
gccagagacatcatgcatgattcaaactacgtgtcaaaaggcagtacctttctccctgtg
aagtggatggctccagagagcatctttgacaacctctacaccacgctgagcgatgtctgg
tcttacggcattctgctgtgggagatcttttctctcggtggcacaccctaccctggcatg
atggtggattctactttctacaataagatcaagagtggctaccggatggccaagcctgac
catgccaccagtgaagtctatgagataatggtgaagtgctggaacagtgagccagagaag
agaccctccttctaccacctcagtgagattgtggagaatctgctgcctgggcattataaa
aagagctacgaaaagattcatctcgacttcctcaagagcgaccatcctgccgtggcgcgc
atgcgtgcggactcggaccatgcctacatcggcgtcccctacaagaacgaggaagacaag
ctgaaagactgggagggcgggctggatgagcagcggctgagcgccgacagtggctacatc
atcccgctgccagacatcgaccctgttcctgaggaggaggaggaagaggaggaggaggac
ctaggcaagaggaacagacacagctcacagacctctgaggagagtgccattgagacgggc
tctagcagttctacattcatcaagagggaggatgagaccattgaagacattgacatgatg
gacgacattggcatagactcctcggacctggtggaggacagcttcctgtaa |
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