| Entry |
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| Symbol |
IDH2
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| Name |
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
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| KO |
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| Organism |
sfum Sorex fumeus (smoky shrew)
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| Pathway |
| sfum05230 | Central carbon metabolism in cancer |
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| Module |
| sfum_M00010 | Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate |
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| Brite |
KEGG Orthology (KO) [BR:sfum00001]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
130023456 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
130023456 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
130023456 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
130023456 (IDH2)
Enzymes [BR:sfum01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
130023456 (IDH2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
452 aa
MAGYLRAARLLCRASGSGPAWAPAALTSPSFPAPLRRHYASKRIKVAKPIVEMDGDEMTR
IIWQFIKEKLILPHVDVELKYFDLGLPNRDLTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTQPITIGRHAHGDQYK
STDFVVDRAGAFKMVFTPTDGSAPTEWAVYDFKAGGVGMGMYNTDESISGFAHSCFQYAL
GKRWPLYLSTKNTILKAYDGRFKDIFQEIFEKHYKPDFEKNKIWYEHRLIDDMVAQVLKS
TGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQELVRFAQTLEKVCVDTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIQRNLNTALGHQ |
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| NT seq |
1359 nt +upstreamnt +downstreamnt
atggctggctacctgcgggccgcgcgcttgctctgcagggcctcgggctccgggccggcc
tgggcgccggcggccctcacgagccccagctttccagcgccgctgcggcgccactatgcc
agcaagaggatcaaggtggcaaagcccattgtggagatggatggggacgagatgacccgt
atcatctggcagttcattaaggagaagcttatcctgcctcacgtggacgtggagctcaag
tattttgacctggggctacctaatcgcgacctcaccaatgaccaggtcaccattgactca
gccctggccacccagaagtacagcgtggctgtcaagtgtgctaccatcacgcctgacgag
gcccgtgtggaagagtttaagctgaagaagatgtggaagagccccaacggcaccatccgc
aacatcctgggcggtaccgtcttccgggagcccatcatctgcaagaacatcccacgcctg
gtccccggctggacgcagcccatcaccattggcaggcacgcgcatggcgaccagtacaaa
tccacggacttcgtggtggaccgggccggtgccttcaagatggtcttcaccccaacagat
ggcagcgcccccactgagtgggcagtgtacgacttcaaggccggtggcgtgggcatgggc
atgtacaacacagatgagtccatctcgggtttcgctcacagctgcttccagtacgccctg
gggaagcggtggccgctctacctcagcaccaagaacaccatcctgaaggcctacgatggg
cgcttcaaggacatcttccaggagatcttcgagaagcattacaagccagacttcgagaag
aacaagatctggtacgagcaccggctcatcgacgacatggtggcccaggtgctcaagtcc
acggggggcttcgtgtgggcctgcaagaactatgacggcgatgtgcagtcggacatcctg
gcccagggctttggctctcttggcctgatgacgtccgtgctggtgtgcccagatggaaag
accatcgaggccgaggctgcccatggtacagtgacccgtcactaccgcgagcaccagaag
ggccggcccaccagcaccaaccccatcgccagcatctttgcatggacgcgtggcctggag
caccggggaaagctggatgggaaccaggagctggtgaggtttgcccagaccctggagaag
gtatgtgtggacaccgtggagagcggagcgatgaccaaggacctggcgggctgcatccat
ggtctcagcaatgtgaagctcaacgagcacttcctcaacacctctgacttcctggacacc
atccagcgcaacctgaacacagccctgggacatcagtag |
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