KEGG   Sorex fumeus (smoky shrew): 130024264
Entry
130024264         CDS       T10594                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum00564  Glycerophospholipid metabolism
sfum00565  Ether lipid metabolism
sfum01100  Metabolic pathways
sfum04014  Ras signaling pathway
sfum04024  cAMP signaling pathway
sfum04071  Sphingolipid signaling pathway
sfum04072  Phospholipase D signaling pathway
sfum04144  Endocytosis
sfum04666  Fc gamma R-mediated phagocytosis
sfum04724  Glutamatergic synapse
sfum04912  GnRH signaling pathway
sfum04928  Parathyroid hormone synthesis, secretion and action
sfum05200  Pathways in cancer
sfum05208  Chemical carcinogenesis - reactive oxygen species
sfum05212  Pancreatic cancer
sfum05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    130024264 (PLD2)
   00565 Ether lipid metabolism
    130024264 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    130024264 (PLD2)
   04072 Phospholipase D signaling pathway
    130024264 (PLD2)
   04071 Sphingolipid signaling pathway
    130024264 (PLD2)
   04024 cAMP signaling pathway
    130024264 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    130024264 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    130024264 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    130024264 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    130024264 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    130024264 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130024264 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    130024264 (PLD2)
   05231 Choline metabolism in cancer
    130024264 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    130024264 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130024264 (PLD2)
Enzymes [BR:sfum01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     130024264 (PLD2)
Membrane trafficking [BR:sfum04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    130024264 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    130024264 (PLD2)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH PH_2
Other DBs
NCBI-GeneID: 130024264
NCBI-ProteinID: XP_055970925
LinkDB
Position
Unknown
AA seq 933 aa
MTATPEGLFPSGEDLDSSQLQMEPDEVDTLREGEDPADRMHPFLAIYNIQPLKTHPLVFA
PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVL
MSLLPLARFAIAYSPDRDAANTEIPSLPRAGPEGSTRHASSKQKYLENYLNRLLTMSFYR
NYHAMTEFLEVSQLSFIPDLGAKGLEGVIRKRSGGHRVPGFTCCGRDQVCYRWSKRWLVV
KDSFLLYMCLETGAISFVQLFDPGFEVQVGKKSTETRYGVRIDTSHRSLILKCSSYRQAR
WWGQEITELAQGPGRDFIQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILQAQEEIF
ITDWWLSPEIYLKRPAHSDDWRLDIMLKKKAEEGVRVSVLLFKEVELALGINSGYSKRTL
MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGESSE
SVTPQPPTSCPNSAATSDLSNNRLFWLGKDYSNLITKDWVQLDRPFEDFIDRETMPRMPW
RDVGVVVHGPSARDLARHFIQRWNFTKTTKAKYKSPAYPYMLPKSTSTANQLPFTLPGGQ
CATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRDYISICGLRTHGELDGHPISELIYIHSKILIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTEMEQSLMDGVEYQAGRFALSLRKHCFSVILGADARPDLDLRDPICD
DFFQLWQDTAENNASIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPSLARSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGVMPLEVWT
NT seq 2802 nt   +upstreamnt  +downstreamnt
atgacggcgacccccgaaggcctcttcccctctggggaggatctggactccagccagttg
cagatggaacccgatgaggtggacactctgagggagggagaggacccagccgaccggatg
cacccctttctggccatctacaacattcagcctctgaaaacacatcctttggtgtttgct
cccggggtccctgtcacggcccaggtggtgggcactgaaagatacaccagtggatctaag
gtggggacatgcactctgtattctgtccgcttaacgcatggcgactttacctggacaacc
aagaagaagtttcgtcatttccaggagctgcaccgcgacctcctcagacacaaagtcttg
atgagtctgctccctttggcccgctttgccatagcctactctccagaccgagatgcagcc
aacacagagattccgtctctcccccgagcaggccccgagggctccactaggcatgcatcc
agcaaacagaaatacctggaaaattacctcaaccgcctcctgaccatgtctttctaccga
aactaccatgccatgacagagttcttggaagtcagtcagctgtcctttatcccagacctt
ggcgccaaaggactggagggagtgatcagaaagcgctcaggcggccatcgtgttcctggc
ttcacctgctgtggccgagaccaagtctgttatcgctggtccaagaggtggctggtggtg
aaggactcctttctgctgtacatgtgcctcgagactggtgccatctccttcgttcagctc
ttcgaccctgggtttgaggtgcaggttggaaaaaagagcacagagacacgatatggggtc
cggatcgacacctctcacaggtcccttattctcaaatgcagcagctaccggcaggcacga
tggtggggccaagaaatcactgagctggctcagggccccggcagagactttatacagtta
caccagcatgacagctatgccccacctcggcccgggactctggctcgatggtttgtgaat
ggggcaggctattttgctgctgtggcagatgccatccttcaagctcaagaggagattttc
atcacagactggtggttgagtcctgaaatatacctgaagcgtccagcccattcagatgac
tggagactcgacattatgctcaaaaagaaggcggaggagggtgtccgggtgtcagtactg
ctgtttaaggaagtggagttggccttgggcatcaatagtggctacagcaaaaggaccctg
atgctgctgcaccccaacataaaggtgatgcgtcacccagaccaggtgacactgtgggcc
catcatgagaaactcctagtggtagaccaagtagtggccttcttaggggggctggacctc
gcctacggccgctgggatgacctacactatcgactgactgatcttggggagtcttctgaa
tcggttaccccacagcctcccacctcctgcccaaactctgcagctacctcagacctctct
aacaaccgattgttctggttgggcaaggactacagcaatcttatcacgaaggactgggtg
cagctggaccggccttttgaagattttattgacagggagaccatgcctcggatgccatgg
cgggacgttggagtggttgttcatggcccctctgcccgcgaccttgcacggcactttatc
cagcgctggaacttcacaaagactaccaaggccaagtacaagtcacctgcatacccatac
atgctgcccaagtccaccagtactgcaaaccagcttcccttcactctcccgggggggcag
tgtgccactgtgcaggtcttacggtcagtggaccgctggtcagcagggactctggagaac
tccatcctcaatgcctatctgcataccatccgggagagccaacacttcctttacattgag
aatcagttcttcattagttgctccgatgggcgaacagttctgaacaaggtgggcgatgaa
attgtggacagaatcctgaaggcccacaaacagggccagtgcttccgagtctacgtgctt
ttgcccctactccctggttttgagggtgatatctccactggtggtggcaactccatccag
gctattctgcacttcacttacagaaccttatgtcgtggggaatactcaatcctacatcgc
ctcaaagcagccatggggacagcgtggcgagactatatttccatctgtgggcttcgtaca
catggagagctagacgggcaccctatctctgagctcatctatatccacagcaagatcctc
attgcagatgacaggacagtcatcatcggttctgcaaacatcaatgaccgaagcttgctg
gggaagcgggatagcgagcttgctgtgctgattgaggacacagaaatggagcagtccctc
atggatggtgtggagtatcaagcgggcagatttgccttgagtttgaggaagcactgtttc
agcgtgattctaggggcagatgcccggccagacttggatcttcgagaccctatctgtgat
gacttcttccaactgtggcaagacacagctgagaataatgctagtatctatgagcagatc
tttcgctgcctgccatccaatgccactcgctctctccggactctccgggaatacgtcgca
gtagagcccctggccacagtgagcccttccttggcccgatcagagctcacccaggtccaa
ggccacctggttcacttccccctcaagttcctggaggatgagtctttgttgcctcccctg
ggtagtaaggagggtgtgatgcctctggaagtgtggacatag

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