KEGG   Sorex fumeus (smoky shrew): 130024953
Entry
130024953         CDS       T10594                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04120  Ubiquitin mediated proteolysis
sfum04380  Osteoclast differentiation
sfum04630  JAK-STAT signaling pathway
sfum04668  TNF signaling pathway
sfum04910  Insulin signaling pathway
sfum04917  Prolactin signaling pathway
sfum04920  Adipocytokine signaling pathway
sfum04930  Type II diabetes mellitus
sfum04931  Insulin resistance
sfum04932  Non-alcoholic fatty liver disease
sfum04935  Growth hormone synthesis, secretion and action
sfum05160  Hepatitis C
sfum05164  Influenza A
sfum05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    130024953 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    130024953 (SOCS3)
   04668 TNF signaling pathway
    130024953 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    130024953 (SOCS3)
   04920 Adipocytokine signaling pathway
    130024953 (SOCS3)
   04917 Prolactin signaling pathway
    130024953 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    130024953 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    130024953 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    130024953 (SOCS3)
   05164 Influenza A
    130024953 (SOCS3)
   05168 Herpes simplex virus 1 infection
    130024953 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    130024953 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    130024953 (SOCS3)
   04931 Insulin resistance
    130024953 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:sfum04121]
    130024953 (SOCS3)
Ubiquitin system [BR:sfum04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     130024953 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 130024953
NCBI-ProteinID: XP_055971772
LinkDB
Position
Unknown
AA seq 218 aa
MVTHSKFPAAGMSRPLDASLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFALQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPAAPPAPSEPAAPPPPPGAPPRRAYYIYSGGEKIPLVLSRPLSSNVA
TLQHLCRKTVNGHLGAYEKVTQLPGPIREFLDQYDAPL
NT seq 657 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgcccgctggacgccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgccgtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggccaacctcctgctc
agcgccgagccggccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacgcagtcgggcaccaagaacctgcgcatccagtgcgagggcggc
agcttcgcgctgcagagcgacccccggagcacgcagcccgtgccgcgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccccggcgcccccgccgcgcccccggcgccc
tccgaacccgccgcgccgccgccgccccccggggcgccgccccgcagagcctactacatc
tactcggggggcgagaagatccccctggtcctgagccggcccctctcctccaacgtggcc
acgctccagcatctctgtcggaagacggtcaacggtcacctgggcgcctacgagaaggtc
acccagctgcccgggcccatccgcgagttcctggatcagtatgacgccccgctctag

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