| Entry |
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| Symbol |
WRN
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| Name |
(RefSeq) bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
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| KO |
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| Organism |
sfum Sorex fumeus (smoky shrew)
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| Brite |
KEGG Orthology (KO) [BR:sfum00001]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:sfum03032]
130025962 (WRN)
03400 DNA repair and recombination proteins [BR:sfum03400]
130025962 (WRN)
Enzymes [BR:sfum01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.4 DNA 3'-5' helicase
130025962 (WRN)
DNA replication proteins [BR:sfum03032]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
130025962 (WRN)
DNA repair and recombination proteins [BR:sfum03400]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
RecQ family DNA helicases
130025962 (WRN)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1434 aa
MSISMMSKKKETQRKLPEWMSVQNKKCDVEEKKSSIQKSVFEDDLPFLEFTGSIMYSYEA
SDCSFLAEDISKSLSDGYVVGFDIEWPPIYHKGQLGKVALIQLCVSESKCYLFHIPSASV
FPQGLKLLLENEAIKKAGVGIEGDQWKLLRDFDVKLKSLVELADVANEKLKCTETWSLNG
LVKHLLGKQLLKDKAVRCSNWNDFPLSETQKLYAATDAYASLVIYRKLEILENDVQIFAI
NKEEKLSPHSVKKQLTSISEEMMKLAEHLPDTLSKCEDSQRMCLLLKDISKSLYSLKKML
LGSSDTKTELHPSSDFSLLPVQNPVAGEAHQKQIRKHKIVSKVKNEKSLDNIENIFEDEV
KQGENKFEDRLEDQSKTNTERTCLMSLDITDYELQILEQQASRKVLSGITCKSPEHLSSE
NNEEDMSYVIESDEDLEIEMLKSLENLNSDTVDPVHSECIEMESNLDLHFEEEDDEDEAI
KEAEEDIDPSLPEPSAEQVTCLKTYFGHSNFKPVQWKVIHSILKERRDNVVVMATGYGKS
LCFQYPPVYEGGIGLVISPLISLMEDQVLQLEMSNIPACFLGSAQSKNVIADLKLGKYRI
VYITPEFCASYLDLLQQLEVNIGFTLIAVDEAHCISEWGHDFRNSYRSLHSLRRVLPLVP
IVALTATATSSIREDIIRCLKLKDPQITLTSFDRPNLYLEVGRKTGNICQDLKQFLVRKT
SSTWNFEGPTIIYCLSRKMTEQVAAQLRLLQVACETYHAGMSIKSRKEVHHKFMRDEIQC
IVATIAFGMGINKADIRRVIHYGAPKEMESYYQEIGRAGRDGLPSSCHLLWAPADIALNW
NRLNEIKNEQFRLYKLKMMAKMRKYLYSSKCRRQIILSHFEDKQLRKASLGIMGTEKCCD
NCRSRLNPCLAIDDTEETLQDFGPQAFQLLSAVNILGEKFGIGVPILFLRGSYSQRLEER
YRKHSFFGIGKDQTESWWKALSYQLVIEGFLIEASGHNKFVKIYKLTKKGRNWLDKANAE
SARKLILQTNEELCSSRHLQSSKTVSSGSRSQQYFSRQEPIELSAERKSNLEKVYSYKTV
DKMSPGKNSPKKSIMVESSGKFSRSSEPVVSAQEQETQTVLYCKLVEARQKHANKMNVPP
AILATNKILLDMAKMRPTTVENVKRIDGVSEGKSTMLAPLLEVIKDFCQLNTIQTDLFSS
AEPQEGLNNRLRVKEACLPSPSVSSTDPLFQEEKMVLKREAENRRLPLTAVGRPLSQAVR
AGYPLQTQGAGLTPEVQKIIADVIRNPPVNSDTSQMKLIRTLVPEDIDTYLIHMAIEILE
KDHNNKSFCQPSYDSSIKRCYPDSEEGCSSSKRHKEEGISTKVNEKCFDDVALKEESQRL
TSWDQPFSDSEIEDLFTDCYPQTSSETSKEKLPAEGNYVRKKTVAKTKKKGLFS |
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| NT seq |
4305 nt +upstreamnt +downstreamnt
atgagcatttccatgatgagtaaaaaaaaggaaacacagcggaaacttcctgagtggatg
tctgtgcagaataagaaatgtgatgtagaagagaaaaagtcatctattcagaagagtgtt
tttgaagatgacctccccttcttagaattcactggatccattatgtatagttatgaagct
agtgattgctctttcttagcagaagatattagcaagagtctatctgatggatatgtggta
ggatttgacatagaatggccgccaatataccacaaagggcaactgggcaaagttgcacta
attcagttgtgtgtgtcagaaagtaaatgttacttgtttcatattccttctgcatcagtt
tttccccagggattaaaactgttgcttgaaaatgaagcaattaaaaaggcaggtgtagga
attgaaggagatcagtggaaactcctacgtgactttgatgttaaattgaagagtctcgtg
gaactagcagatgttgccaatgaaaagttgaaatgtacagagacatggagcctcaatggt
ttggttaaacatctcttaggtaaacagcttctgaaagataaagctgttcgctgtagcaac
tggaatgattttcctctcagtgaaacacagaagctgtatgcggcaacggatgcttatgct
agtctcgtcatttatcgaaaactggaaattttggagaatgatgtgcaaatatttgctata
aataaagaggagaaattatcaccccacagtgtgaagaaacagttgacttccatctctgag
gagatgatgaagctggctgaacaccttccggatactttaagcaaatgtgaagactcacag
aggatgtgtttactgctaaaggatatttcaaaaagtttgtattcattgaaaaagatgcta
ttaggttcttctgacaccaagactgaactgcaccccagcagtgatttcagcttattgcca
gttcagaatccagttgctggtgaagcacatcagaaacaaattaggaaacataaaattgtt
agtaaagttaaaaatgagaaatctcttgataatatagaaaatatatttgaagatgaagta
aaacaaggagaaaataaatttgaagatcgattagaagaccaatcaaaaacaaatacagag
agaacttgtttgatgtcattagatattacagattatgaactccaaattttggaacagcag
gcttccagaaaagttctgagtggtattacttgcaaatctccggagcatttgtcttctgag
aataatgaagaggatatgtcttatgtaattgaaagtgatgaagatttagaaattgagatg
cttaagtctttagaaaacctaaatagtgacacagtggatccagttcattcagaatgtata
gaaatggaaagtaatctggatcttcattttgaagaagaggatgatgaggatgaagcgatt
aaagaggcagaagaagatattgacccttcattaccagaacctagtgcagagcaagttact
tgcctcaagacctactttggccattccaattttaagcctgttcaatggaaagtaattcat
tcgatactgaaagaaagacgagataatgttgttgtcatggcaactggatatggaaagagt
ttgtgcttccagtatcctccggtttatgaaggtgggatcggccttgtgatctctcctctt
atttctttgatggaagaccaagtgctccagctcgaaatgtccaacattccagcttgtttt
cttggatcagcacagtcaaaaaatgttatagcagatcttaaattaggcaaatatcgaatt
gtatacataacaccagaattctgtgctagttacttggacctactccagcaacttgaagta
aatattggattcactcttattgctgtggatgaggcacactgtatttctgagtggggacat
gattttagaaattcatacagatctctgcactctctgaggagagtactcccgttggtgcca
attgttgcactcactgctacagcaacttcttcaatccgggaagacattattcgttgttta
aaactgaaggatcctcagattactcttactagttttgatcggccaaacttgtacttagaa
gttggacgaaaaactggaaatatttgtcaggatctgaagcaatttcttgtcagaaagaca
agttctacgtggaattttgaaggcccaactatcatctattgtctttctagaaaaatgaca
gaacaagttgcagctcaacttaggttgctgcaggtagcctgtgaaacataccatgcggga
atgagtattaagtccaggaaagaggtgcatcacaagttcatgagagatgaaattcagtgc
atcgtagctaccatagcttttggaatgggaattaataaagctgacattcgcagagtcatt
cattatggtgctcctaaggaaatggaatcatattaccaggagattggtagagctggtcga
gatgggcttccaagttcctgccacttgctctgggctccagcagacattgctttaaattgg
aaccgccttaatgagataaaaaatgaacagtttcgattatacaaattaaagatgatggca
aagatgagaaaatacctttattccagcaagtgtaggcgacaaatcatcttgtctcatttt
gaagataaacaactacgaaaagcctccttgggtattatgggaactgaaaaatgctgtgat
aattgcagatccagattaaatccttgccttgcaattgatgatacagaggagactctacag
gactttggtccacaagcattccagttattatctgctgtgaacattttaggagaaaaattt
ggaattggggttccaattttgtttctccgaggatcttattcccaacgtcttgaagaaaga
tatcgcaagcacagtttttttggcattggcaaagatcaaacggagagttggtggaaggct
ttatcttatcagctcgttattgagggattcttgatagaggcttctggacacaacaaattt
gtgaagatttacaaacttacaaaaaagggtagaaattggcttgataaagccaatgccgag
tctgctcggaaacttatccttcaaactaatgaagaattatgttcatcgaggcatctacaa
agttctaaaactgtgtcttcaggcagtcgcagtcaacagtatttctctagacaagaacca
attgaattaagtgcagagaggaagtctaacttggagaaggtttattcttacaaaacagtt
gataagatgtctcctgggaaaaacagtcctaaaaaaagcatcatggtggagtcatcaggg
aaattttccagatcttcagaacccgtggtctcagctcaagagcaggagactcagactgtg
ttatattgcaaattagtagaagccaggcagaaacatgccaataaaatgaatgttccacca
gccattctggcaacaaataagatattgctggatatggccaaaatgagacctactactgtt
gaaaatgtgaaaaggattgatggggtttctgaaggcaaatctaccatgttggcccctctc
ttggaagttatcaaagatttctgtcagttaaatactattcagacagacttattttcaagt
gcagaacctcaggaaggactgaacaacagactgagggtgaaggaagcctgtttgccgtca
ccatccgtgtccagcacagaccctttattccaagaagagaagatggttttgaagcgtgaa
gctgagaacaggagactgccgctcacagcagttggcaggcccttatcccaagcggtgagg
gctggctacccactccagacgcagggagcaggcctgactccagaggttcagaagattatt
gctgatgttatccgaaaccctcccgtcaactcagatacgagtcaaatgaaactaattaga
acgttagttcctgaagacattgacacatatcttatccacatggcaattgaaattctggaa
aaagatcataataataaatcgttctgccaaccttcatacgattccagcataaagaggtgt
taccctgactctgaagagggctgttcaagttctaagagacacaaggaagaaggcattagt
acgaaggtcaatgagaaatgttttgatgatgttgcattgaaagaagaaagtcagagacta
acttcttgggaccagccattcagcgattcagaaatagaggatctgtttacagattgttac
ccacagacttcctctgagacttcgaaggaaaaattacctgccgaaggaaattatgtcaga
aaaaaaacagtagccaaaacaaaaaagaagggtctttttagttag |
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