KEGG   Sorex fumeus (smoky shrew): 130026526
Entry
130026526         CDS       T10594                                 
Symbol
ABCA1
Name
(RefSeq) phospholipid-transporting ATPase ABCA1 isoform X1
  KO
K05641  ATP-binding cassette, subfamily A (ABC1), member 1
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum02010  ABC transporters
sfum04148  Efferocytosis
sfum04975  Fat digestion and absorption
sfum04979  Cholesterol metabolism
sfum05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    130026526 (ABCA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    130026526 (ABCA1)
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    130026526 (ABCA1)
   04979 Cholesterol metabolism
    130026526 (ABCA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    130026526 (ABCA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:sfum02000]
    130026526 (ABCA1)
Transporters [BR:sfum02000]
 ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    130026526 (ABCA1)
SSDB
Motif
Pfam: ABC_tran ABC2_membrane_3 R1_ABCA1 AAA_21 DUF4162 AAA_23
Other DBs
NCBI-GeneID: 130026526
NCBI-ProteinID: XP_055973350
LinkDB
Position
Unknown
AA seq 2263 aa
MACWPQLRLLLWKNLTFRRRQTLQLLLEVAWPLFIFFILISVRLSYPPYEQHECHFPNKA
MPSAGTLPWIQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVSRLFSDAQRLLLYSQRDT
SMKDIRKVLRTLQRIENSSSNLKLRDFLRDNETFSVFLNHNLSLPRPTVDRLLGADVSLR
KVFLHGYQLHLTNLCNGSKLEEVIKLGEQDISRLCVLPQEKLDATERVLRANMDILKPVV
VKLNSTSPIPTNELAEATKTLLDSLGTLAQELFSMRSWSDMRQEVLFLTDVNSSRTSTQI
YQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGNSTEDEAGAFYDNSTTPHCNDLMK
NLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELS
PKIWTFMESSSEMDLVRTLLDSRGNEHFWEQRLDGVGWTAKDIVTFLAKHPEDVQSTNGS
VYTWREAFNETNRAVQTISRFMECVNLNKLEATATEVRLINKSMELLDERKFWAGIVFTG
ITPGSAELPHHVKYKIRMDIDNVERTNKIKDAYWDPGPRADPFEDMRYVWGGFAYLQDIV
EQAIIRVLTGTEKKTGVYVQQMPYPCYVDDIFLRVVSRSMPLFMTLAWIYSVAVIIKGIV
YEKEARLKETMRIMGLDNGILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFV
FLSMFAVVTILQCFFISTFFSRANLAAACGGIIYFTLYLPYVLCSAWQDHVGFMLKIFVS
LLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEGDGFNLTTSVTMMLFDTFLYGVMTW
YIEAVFPGQYGIPRPWYFPCTKSYWFGEECAEKSPPGSSQKGATEICMEEEPTHLKLGVS
IQNLMKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYIL
GKDIRSEMSTIRQNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVG
LPPSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ
GRTIILSTHHMDEADILGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVDSSLS
SCRNSSSTVSYLKKVVPELLPAGQSGGRGGEVQRLVALTQDVSAISNLIRKHVTEARLVE
DIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEESGVD
AETSDGTLPARRNRRAFGDKQSCLRPFTEDDVMDPNDSDIDPESRETDLLSGMDGKGSYQ
VKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLE
LQPWMYNEQYTFFSNDAPEDMATQELLNALTREPGFGTRCMDGHPIPDTPCLVGEEEWTT
APVPQTIMDLFQDGNWTMDNPSPACQCSNDRIKKMLPVCPLGAGGLPPPQRRQNTADILQ
NLSGRNISDYLVKTYVQIIAKSLKNKFWVNEFRYGGFSLGASNSQSLPPSQEVNDAIKQV
KKHLKVAKDSSADRFLSSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANL
QKGEKPGQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQ
ERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVL
ALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTNNKLNN
INDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAV
EGVVFFLITVLIQYRFFIRPRSVNTKLLPLNDEDEDVRRERQRILDGGGQNDILEIKELT
KIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTSVTRGDAFLNKNSIL
SNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYG
EKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVV
LTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQEF
FGLAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFV
NFAKDQSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVKESYV
NT seq 6792 nt   +upstreamnt  +downstreamnt
atggcttgttggcctcagctaaggttgttgctgtggaagaatctcacttttcgaagaaga
caaacacttcaactactgctggaagtggcctggcctttgtttatcttcttcatcttgatc
tctgtccggttgagctacccaccctatgagcagcatgaatgccactttccaaacaaagcc
atgccctctgcaggaacgctgccttggattcaggggattatctgtaatgccaacaacccc
tgcttccgttacccaactcctggtgaggctcctggggttgttggaaactttaacaaatcc
attgtgtcccgcctcttctccgatgcgcagcggcttcttttgtatagccagagagacacc
agcatgaaggacatccgtaaagttctgcgaacattacagcggatcgagaattccagctca
aacctgaagcttcgggatttccttcgggacaatgaaaccttctctgtgttcctgaatcac
aacctctctctgccaaggcctactgtggacagactgctgggcgctgatgttagtctccgg
aaggtgtttttgcatggctaccagttacatttgaccaacctttgcaatggatccaaatta
gaagaggtgattaagcttggtgagcaggatatttccagactgtgtgtcctgcctcaggag
aaactggatgcaacagagcgagtccttcgtgccaacatggacatcctgaagccagttgtg
gtaaaactaaactccacatctcccattcccaccaacgagctggctgaagccaccaaaact
ttgctggatagccttggaactctcgcccaagagctgttcagcatgaggagctggagtgac
atgcgccaagaagtgctgttcctgaccgatgtgaacagctccaggacctccacgcagata
taccaggctgtgtcccgcatcgtctgtggccaccccgaggggggaggcctgaagatcaag
tcgctcaattggtatgaggacaacaattacaaggccctgttcggaggcaacagcaccgag
gacgaggccggcgccttctatgacaactccaccactcctcactgcaacgatctgatgaaa
aatctggagtccagtcctctttctcggatcatctggaaagctctcaagcctctgctagtc
gggaagatcctgtatacacctgacactccagccaccaggcaggtgatggctgaggtgaat
aagactttccaggaattggctgtgttccatgatctggaaggcatgtgggaagagcttagc
cccaagatttggaccttcatggaaagcagctcagaaatggaccttgtccggactctgttg
gacagcagaggcaacgagcacttctgggaacagcgtttggatggtgtaggctggacagcc
aaagacattgtgacatttctggccaagcacccagaagatgtccagtccactaatggctct
gtgtatacttggagagaagccttcaatgagaccaaccgagcagtgcagaccatatcccgc
ttcatggagtgtgtcaacttgaacaagctggaagcaacagcaacagaagttcgactcatc
aataagtccatggagttgctggatgagaggaagttctgggctggtattgtgtttaccgga
attactcccggcagtgcagagctgcctcatcatgtcaaatataagatccgaatggacatt
gacaatgtggagaggacaaataagatcaaagatgcgtactgggaccctggtcctcgagct
gacccctttgaagatatgcggtacgtctggggtggctttgcttacttgcaggacatagtg
gaacaggcgatcatcagggtactcactggcactgagaagaaaactggggtctacgtgcag
cagatgccgtacccttgctacgttgatgacatcttcctgagagtggtgagccggtcaatg
cctctctttatgaccctggcctggatctactccgtggctgtgatcatcaagggcattgtg
tatgagaaggaggcgcggctgaaggagaccatgcgcattatgggcctggacaatggcatc
ctgtggttcagctggttcatcagcagcctcatccccctgcttgtgagcgccggcctgctg
gtggtcatcctgaaattggggaacctgctgccgtatagcgacccgagcgtggtgttcgtc
ttcctgtccatgtttgccgtggtgaccatcctgcagtgcttctttatcagcaccttcttc
tccagagccaacctggcagctgcctgcgggggcatcatctacttcacactgtacctgccc
tatgtcctgtgctcggcctggcaagaccacgtgggcttcatgctcaagatctttgtgagc
ctgctgtctcctgtagcttttgggtttggctgcgaatactttgccctctttgaggagcag
ggcattggggtgcagtgggataacctctttgagagccccgtggagggagatggcttcaac
ctcaccacctcagtcaccatgatgctgttcgacaccttcctgtatggggtgatgacttgg
tacatcgaggccgtctttccaggccagtacgggattcccaggccctggtattttccctgc
accaagtcctactggtttggggaggaatgtgctgagaagagcccccctggttccagccag
aagggagcaacagaaatctgcatggaggaggagcccacacacctgaagctgggcgtgtcc
atccagaatctgatgaaggtttatcgagatggcatgaaggtggctgtggatggtctggcc
ctgaacttttacgagggacagatcacctccttcctgggccacaatggagccgggaagacc
accaccatgtcaatcctgaccgggttgttcccgcccacctcaggcactgcctacatcctg
ggaaaagacattcgctcggagatgagcacgatccggcagaacctgggtgtctgtccccag
cacaacgtgctgtttgacatgctgactgttgaggaacacatctggttctatgctcgcctg
aaagggctctcagagaagcacgtgaaggcggagatggagcagatggccctggatgtgggt
ttgccccccagcaaactgaaaagcaagacaagccaattgtcaggtggaatgcagaggaag
ctgtctgtcgctttggcctttgtcgggggatccaaagttgtcattctggatgagcccaca
gctggcgtggacccctactcccgcaggggaatatgggagctgctccttaagtatcggcaa
ggtcgcaccatcattctctccacccaccacatggacgaagcagacatcctaggggaccgg
atcgccatcatctcccacgggaagctgtgctgtgtgggctcctccctctttctaaagaac
cagctgggaacaggctactacctgaccttggtcaagaaggacgtggactcctcgctcagc
tcctgcagaaatagcagcagtactgtgtcatacctgaaaaaggtggtgcctgagcttctc
ccagctgggcagagtggaggcagaggaggagaggtgcagaggctggtggcgctgactcaa
gatgtctctgctatctccaacctcatcaggaagcatgtgaccgaggcccggctggtagag
gacattgggcatgagctgacatacgtgctaccctatgaagctgccaaagagggggccttt
gtggagctcttccatgagatcgatgacaggctatcagatctgggcatctcaagttatggc
atctcagagaccaccctagaagaaatatttctcaaagtggctgaagaaagtggagtggat
gcagagacctcagatggaaccttgccagcaagacgaaatagacgggcctttggggacaag
cagagctgtcttcgcccattcactgaagatgatgtgatggatcccaatgattccgacata
gacccagaatccagagagacagacctgctcagtgggatggacggcaaaggctcctatcag
gtgaagggctggaagctcacacagcagcagtttgtggccctgttgtggaagagattgctc
atcgcccgaaggagccggaagggattcttcgctcagattgtcctgccagctgtgttcgtc
tgcattgccttggtattcagcttgatcgtgccaccctttggcaagtaccccagcctggaa
cttcagccctggatgtacaatgaacagtatacatttttcagtaatgatgctccggaagac
atggccacccaggaactcttgaatgccctcaccagagaacctggctttggaactcgctgt
atggacggacacccaatcccagacacgccctgcttggtaggggaggaggagtggacgact
gccccagttccccagactattatggacctcttccaagatgggaactggaccatggacaac
ccttcccccgcctgccagtgtagtaatgacagaatcaagaagatgctgcccgtgtgtccg
ctgggagcaggggggctgcctcctccacagagaagacagaacacagcggacattcttcag
aacctatccgggagaaacatttcagattatctggtgaagacttatgtgcagatcatagcc
aaaagcctaaagaacaaattttgggtgaatgaatttaggtatggtggattttctctgggt
gccagtaattcccagtcacttcctccaagtcaagaagttaatgatgccatcaagcaagtg
aagaaacacttaaaggtggccaaggacagttcggcagatcggtttctcagcagcttggga
aggttcatgacaggattggacaccaaaaataacgtcaaggtgtggttcaataacaagggc
tggcatgccatcagctctttcttgaacgtcatcaacaatgcaattctccgggccaacctg
cagaagggagagaagcctggccaatatggcatcactgctttcaaccacccgctgaacctc
accaaacagcagctctcggaagtggctctgatgaccacatcagtggatgtccttgtgtcc
atctgtgtcatctttgcgatgtcctttgtcccagccagctttgttgtattcctgatccag
gagcgggtcagcaaagctaagcacctgcagttcatcagtggagtgaagcccgtcatctat
tggctctctaattttgtctgggacatgtgcaactatgtggttcctgccacgctggtcatt
atcatcttcatctgcttccagcaaaaatcctatgtgtcctccactaacctgcctgtgcta
gcccttctccttctgctgtatgggtggtcgatcaccccgctcatgtaccctgcctccttc
gtgttcaagatccccagcacagcctatgtggtcctgaccagcgtgaacctcttcattggc
atcaatggcagcgtggctacttttgtgctggagctcttcaccaacaataagctgaataac
atcaatgatatcctgaagtctgtgttcctgatcttcccacacttctgtttgggacggggg
ctcattgacatggtgaagaaccaggcaatggcggatgccttggaaagatttggagagaat
cgctttgtctcacctctgtcttgggacttggtgggtcgaaaccttttcgccatggctgtg
gaaggggtggtgttcttcctcatcactgttctcatccagtacagattcttcatcagaccc
agatctgtaaatacaaagcttctacctctgaatgatgaagatgaagatgtcaggcgggaa
aggcagagaattctcgatggaggaggacagaatgacatcttggaaatcaaggagctgacc
aagatatatagaaggaagaggaagcctgctgttgacagaatttgtgttggcattcctcct
ggagagtgttttgggcttctgggagtgaatggggcaggtaaatcatcaactttcaagatg
ttaactggagatacttctgttacaagaggagatgctttccttaacaaaaacagtatctta
tcaaacatccacgaagtacatcagaacatgggatattgccctcaatttgatgctatcaca
gagctgctaactgggagagaacatgtggagttctttgccctcttgaggggagtcccggag
aaggaagtcggcaaggttggtgagtgggcaattcggaaactgggccttgtgaaatacgga
gaaaaatatgctggtaactacagtggaggtaacaagcgcaagctctcgacagccatggct
ttgatcggcggaccgcctgtggtgttcctggatgaacccactacaggcatggatcccaaa
gcccggcggttcctgtggaattgtgccctcagtgtggtcaaggaggggagatcagtggtg
cttacatctcatagtatggaagaatgtgaagctctttgcacccggatggcaattatggtc
aatgggaggttcagatgtcttggtagtgttcaacatctgaaaaataggtttggagatggc
tatacgatagttgtacgaatagcaggatccaaccctgatctgaagcctgtccaggagttc
tttggacttgcttttccaggaagtgtcttaaaagagaagcaccggaacatgctccagtac
cagcttccatcctcattatcttccttggcaaggattttcagcatcctttcccagagtaaa
aagagactccacatagaagattactctgtttctcagacaacacttgaccaagtatttgta
aactttgccaaggaccaaagtgatgatgaccacttaaaggacctgtcattacacaaaaac
cagacagttgtggatgttgcagttctcacgtcttttctacaggatgagaaagtgaaggaa
agttatgtatga

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