KEGG   Sorex fumeus (smoky shrew): 130026854
Entry
130026854         CDS       T10594                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum01521  EGFR tyrosine kinase inhibitor resistance
sfum01522  Endocrine resistance
sfum04010  MAPK signaling pathway
sfum04014  Ras signaling pathway
sfum04015  Rap1 signaling pathway
sfum04066  HIF-1 signaling pathway
sfum04068  FoxO signaling pathway
sfum04081  Hormone signaling
sfum04114  Oocyte meiosis
sfum04115  p53 signaling pathway
sfum04150  mTOR signaling pathway
sfum04151  PI3K-Akt signaling pathway
sfum04152  AMPK signaling pathway
sfum04211  Longevity regulating pathway
sfum04213  Longevity regulating pathway - multiple species
sfum04510  Focal adhesion
sfum04550  Signaling pathways regulating pluripotency of stem cells
sfum04730  Long-term depression
sfum04750  Inflammatory mediator regulation of TRP channels
sfum04913  Ovarian steroidogenesis
sfum04914  Progesterone-mediated oocyte maturation
sfum04935  Growth hormone synthesis, secretion and action
sfum04960  Aldosterone-regulated sodium reabsorption
sfum05200  Pathways in cancer
sfum05202  Transcriptional misregulation in cancer
sfum05205  Proteoglycans in cancer
sfum05214  Glioma
sfum05215  Prostate cancer
sfum05218  Melanoma
sfum05224  Breast cancer
sfum05410  Hypertrophic cardiomyopathy
sfum05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130026854 (IGF1)
   04014 Ras signaling pathway
    130026854 (IGF1)
   04015 Rap1 signaling pathway
    130026854 (IGF1)
   04066 HIF-1 signaling pathway
    130026854 (IGF1)
   04068 FoxO signaling pathway
    130026854 (IGF1)
   04151 PI3K-Akt signaling pathway
    130026854 (IGF1)
   04152 AMPK signaling pathway
    130026854 (IGF1)
   04150 mTOR signaling pathway
    130026854 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    130026854 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    130026854 (IGF1)
   04115 p53 signaling pathway
    130026854 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    130026854 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    130026854 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    130026854 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    130026854 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    130026854 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    130026854 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    130026854 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    130026854 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    130026854 (IGF1)
   04213 Longevity regulating pathway - multiple species
    130026854 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130026854 (IGF1)
   05202 Transcriptional misregulation in cancer
    130026854 (IGF1)
   05205 Proteoglycans in cancer
    130026854 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    130026854 (IGF1)
   05218 Melanoma
    130026854 (IGF1)
   05215 Prostate cancer
    130026854 (IGF1)
   05224 Breast cancer
    130026854 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    130026854 (IGF1)
   05414 Dilated cardiomyopathy
    130026854 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    130026854 (IGF1)
   01522 Endocrine resistance
    130026854 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:sfum04052]
    130026854 (IGF1)
Cytokines and neuropeptides [BR:sfum04052]
 Cytokines
  Growth factors (RTK binding)
   130026854 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 130026854
NCBI-ProteinID: XP_055973535
LinkDB
Position
Unknown
AA seq 167 aa
MGKISSLPTQLFKCCFCDFWKVKMHIKPSSNLFYLILCLLTFTSSASAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKAARS
VRAQRHTDMPKAQKSSSPSINKKMKSQRRRKGGPKKRPGGEQKEGQK
NT seq 504 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttctgg
aaggtaaagatgcacatcaagccctcctcgaatctcttctacctgatcctgtgtttgctc
accttcaccagctctgcctctgctggaccagagacactctgcggggctgagctggtggat
gctcttcagttcgtgtgtggcgacaggggcttttatttcaacaagcccacggggtacggc
tccagcagtcggagggcacctcagacgggcatcgtggacgagtgctgcttccggagctgt
gacctgagacggctggagatgtactgtgcacccctgaagcctgccaaggcagcccgctcc
gtccgagctcaacgccacactgacatgcccaaagctcaaaagtcttcgtccccatctatc
aacaagaaaatgaagtcccaaaggagaaggaaaggtgggccaaagaaacgcccaggaggg
gaacaaaaggaggggcagaagtaa

DBGET integrated database retrieval system