Sorex fumeus (smoky shrew): 130027753
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Entry
130027753 CDS
T10594
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum02010
ABC transporters
sfum04024
cAMP signaling pathway
sfum04152
AMPK signaling pathway
sfum04530
Tight junction
sfum04971
Gastric acid secretion
sfum04972
Pancreatic secretion
sfum04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
130027753 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
130027753 (CFTR)
04152 AMPK signaling pathway
130027753 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
130027753 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
130027753 (CFTR)
04972 Pancreatic secretion
130027753 (CFTR)
04976 Bile secretion
130027753 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
sfum02000
]
130027753 (CFTR)
Enzymes [BR:
sfum01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
130027753 (CFTR)
Transporters [BR:
sfum02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
130027753 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_29
AAA_21
T2SSE
AAA_16
DO-GTPase2
nSTAND3
DUF87
RsgA_GTPase
MMR_HSR1
AAA_23
NACHT
MeaB
Zeta_toxin
NTPase_1
AAA_30
NB-ARC
Motif
Other DBs
NCBI-GeneID:
130027753
NCBI-ProteinID:
XP_055974583
LinkDB
All DBs
Position
Unknown
AA seq
1483 aa
AA seq
DB search
MQRSPLEKASVISKLFFSWTTPILRKGYRQRLELSDIYQIPSADSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWKFMFYGILLYLGEVTKAVQPLLLGRIIASYDPDNTAERSIA
IYLGIGLCLLFIMRTLLLHPAIFGLHHIGMKMRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWELLQASAFCGLAFLIIIALFQSGL
GRMMMKYRDKRAGKINERLVITSEMIENIQSVKAYCWEEAMEKIIENLRETELKLTRKAA
YVRYFNSSAFFFSGFFVVFLSVLPYALLKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVEMVNATAYWEEGLGGLFEKAKENNNNND
SGISNGDNSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPS
EGKIKHSGRISFCPQFSWIMPGTIKENIIFGVSYDEYRYKSVIKACQLEEDISKFAEKDN
IVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANK
TRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSKLMGYDSFDQFSAERR
NSILTETLRRFSLEGDAAVSWNEARKQSFKQTGEFGEKRKNSLLNPINSIRKFSIAQKTP
IQMNGIEEDSEESLERRLSLIPDSERGEAILPRSNVIHTGPTFQGCRRQSVLNLMTHSSV
NQGSNIYRRATASARKMSLAPQGNFTEMDIYSRRLSQDSILEISEEINEEDLKECFFDDV
DKMPTVTTWNTYLRYVTAHKNLIFVLVWCLVIFLAEVALSLVVVKLFESKPPDKGNSTEI
PNSTHAVIITETSAYYIFYIYVGVADTLLALGIFRGLPLVHTLITVSKILHHKMLHSVLH
APMSTLNALKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAVTVVSVLQPYIFLA
TVPVIAAFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLF
HKALNLHTANWFLYLSTLRWFQMRIEIVFVLFFIVVTFISILTTGEGQGNIGIVLTLAMN
IMNTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEESKPTKAVKASKGAPLSEVMIIENQH
AKKDDIWPSGGQMTIKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAL
LRLLKTEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFNGTFRKNLDPYDQWNDQEIWK
VTEEVGLKSVIEQFPGKLDFVLMDGGYVLSHGHKQLICLARSVLSKAKILLLDEPSAHLD
PITYQIIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENKVRQYDSIQKLLSEKSLF
RQAISSSDRLKLFPHRNSSKYKSRSKITALKEETEEEVQETRL
NT seq
4452 nt
NT seq
+upstream
nt +downstream
nt
atgcagaggtcgcccctggaaaaggccagcgtcatctccaaactttttttcagctggact
acaccaattttgagaaaagggtacagacagcgcttggaactgtcagacatataccaaatc
ccttctgctgattctgctgataatctatctgaaaagttggaaagagaatgggacagagag
ctggcttccaaaaaaaatcccaaactaattaatgcccttcgacgatgctttttctggaaa
tttatgttctacggaatcttattatatttaggggaagtgaccaaggcagtgcagccactc
ttacttggaagaatcatagcttcctatgatccagataacactgcagaacgctctattgcc
atttatctaggcataggcctatgccttctttttattatgagaacactgctcctgcatcca
gccatttttggccttcatcatattggaatgaaaatgagaatagctatgttcagtttaatt
tataaaaagactttaaagctatcaagtagagttttagataaaataagcattggacaactt
gttagtcttctttctaacaacctcaacaaatttgatgaaggacttgccttggcacatttt
gtgtggattgctcctttacaagtgacacttctgatgggacttctctgggagttgttacag
gcatctgccttctgtggacttgctttcctgataattattgcccttttccaatctggctta
ggaagaatgatgatgaaatacagagataagagagctggaaagatcaatgaaagacttgta
atcacctcggaaatgattgaaaatatacagtctgttaaggcatactgttgggaggaagca
atggaaaaaataattgaaaacctcagagaaacagaactgaaactgacccggaaggcagcc
tatgtgagatacttcaatagctcagctttcttcttctcagggttttttgtagtgttcttg
tccgtgcttccctatgcgttgctcaaaggcattatccttcgaaaaatattcaccaccatc
tcattctgcattgttctgcgcatggcagtcacacggcagtttccttgggctgtacaaaca
tggtatgactctcttggagccatcaacaaaatacaggatttcttgcaaaagcaagagtat
aagacattggagtataacttaacaactacagaagtagagatggtgaatgcaacagcttac
tgggaagagggacttgggggattatttgaaaaagcaaaagaaaataataataataacgat
agtggcatttccaatggtgataacagcctcttcttcagcaacttctcacttcttggtact
cctgtcctgaaagatatcaattttaaaatagaaagaggacaattgttggcagttgctgga
tctactggagcgggcaagacctcacttctaatgatgattatgggagaactggagccttca
gaagggaaaattaagcacagtggaagaatttcattctgccctcaattttcctggatcatg
cctggaaccataaaagaaaatatcatctttggtgtttcctatgatgagtacagatataaa
agtgtcatcaaagcatgtcaattagaagaggatatctccaaatttgctgagaaagacaac
atagttcttggagaaggtggaatcaccttgagtggaggtcaacgagccagaatttcttta
gcaagagcagtatacaaagatgctgatctgtacctgttggactctccttttggttacctt
gatgttttaacagaaaaagaaatatttgaaagctgtgtctgtaaattgatggctaacaaa
actaggattttggtcacttctaaaatggagcatttaaagaaagccgacaaaatattaatt
ttacatgaagggagcagctatttttatggaacattttctgaactacaaaatctacggcca
gacttcagctcaaagctcatgggatatgattcttttgatcagtttagtgcagaaagaaga
aattccatcctaacggagactttacggcgtttctcgttggaaggggatgctgctgtctcc
tggaatgaagccagaaagcaatcttttaaacagacgggagagtttggtgaaaaaagaaag
aactctcttctcaatccaatcaactctatacgcaagttttcgattgctcaaaagacacca
atacaaatgaatggtattgaagaagactctgaggagtccttagaaagaagactgtccctg
attccagattctgagcggggggaggccatccttcctcggagcaatgtcatccacactggt
cccactttccagggctgccggaggcagtctgttctgaatttgatgacgcattcctcagtg
aaccaaggttcaaacatttaccgaagggcaacagcatctgctcgaaaaatgtccctggcc
cctcaggggaacttcaccgaaatggatatatactcaagaaggttatctcaagacagcatc
ttggaaataagtgaagaaatcaatgaggaagatttgaaggagtgcttttttgatgatgtg
gacaagatgccaacagtgaccacgtggaacacataccttcgatatgttactgctcataag
aatttaatttttgtgctagtttggtgtttagttatttttctggctgaggtggctctgtct
ctggttgtagtcaagctatttgaaagcaaacctccagacaaaggaaatagtactgagatt
ccaaatagcacccatgccgtgatcatcactgagaccagtgcatattatattttttacatt
tatgtgggagtcgctgacactttgcttgctctggggatttttagaggtctgccactggta
cacactctgatcacagtgtcaaaaatattacaccacaaaatgctgcattctgttcttcat
gcacctatgtcaaccctcaacgcactgaaagcaggtgggattcttaacagattctccaaa
gatatagcaattttggatgatcttctgcctcttaccatatttgacttcattcagttgctt
ttaattgtgatcggagctgtgacagtggtctcggttttacaaccctacatcttcctagca
acagtgccagtgatagctgcttttattttattgagagcctacttcctccacacctcacag
cagctcaaacaactagagtctgaaggcagaagtccaattttcactcatcttgttacaagc
ttaaaaggactgtggacacttcgtgcttttgggcgacagccttactttgaaactctgttc
cataaagcgctaaacttacatacagccaactggtttttgtacctatcaactctgcgctgg
ttccaaatgaggatagaaattgtttttgtcctcttcttcattgtcgttaccttcatttcc
attttaacaacaggtgaaggacaaggaaatattggtattgtactaactttagccatgaat
attatgaatacattgcagtgggctgtaaattccagcatagatgtggatagcttgatgcga
tctgtgagccgagtcttcaaatttattgatatgccaacagaagaaagtaaacctaccaag
gcagtcaaggcgtccaagggtgctccactctcagaagttatgattattgagaatcaacat
gcaaaaaaagatgatatctggccctcaggaggccaaatgaccatcaaagacctcactgca
aaatatatagatggagggaatgccatattagagaacatttccttctctataagtcccggc
cagagggtgggtcttttgggaagaactgggtcagggaagagtactttgttatcggctctt
ttgagactgctgaaaacagaaggagaaatccaaattgatggtgtgtcttgggattcaata
actttacaacagtggaggaaagcttttggagtcataccacagaaagtatttatatttaat
ggaacctttagaaaaaacctggatccctatgatcagtggaatgatcaagaaatatggaaa
gttacagaagaggttgggctcaaatctgtgatagagcaatttcctggaaaacttgacttt
gttcttatggatggaggttatgtcctaagtcatggtcacaagcaattgatatgcttggcc
aggtctgttctcagtaaagcaaagatcttgctgcttgatgaacccagtgctcatttggat
ccaataacatatcaaatcattcgaagaaccctaaagcaagcgtttgctgattgcacagta
atcctctgcgagcacaggatagaggcaatgttggaatgccaacgatttttagtcatagag
gagaacaaagtacggcagtatgattccatccagaagctgctgagtgagaagagcctcttc
cggcaggccatcagctcctcggaccgcttgaagctcttcccacatcgaaattccagcaag
tacaaatcccgatccaaaatcactgccctcaaggaggagacggaagaagaggtgcaagaa
acacggctttaa
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integrated database retrieval system
