Sorex fumeus (smoky shrew): 130028252
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Entry
130028252 CDS
T10594
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum01522
Endocrine resistance
sfum04330
Notch signaling pathway
sfum04658
Th1 and Th2 cell differentiation
sfum04919
Thyroid hormone signaling pathway
sfum05165
Human papillomavirus infection
sfum05200
Pathways in cancer
sfum05206
MicroRNAs in cancer
sfum05207
Chemical carcinogenesis - receptor activation
sfum05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
130028252 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
130028252 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
130028252 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
130028252 (NOTCH2)
05206 MicroRNAs in cancer
130028252 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
130028252 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
130028252 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
130028252 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
130028252 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
EGF_2
Ank_2
Ank
NOD
Notch
NODP
Ank_5
Ank_3
Ank_4
EGF_Teneurin
EGF_3
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
130028252
NCBI-ProteinID:
XP_055975004
LinkDB
All DBs
Position
Unknown
AA seq
2471 aa
AA seq
DB search
MRVPRPARPWVLLALWLCGATPARALQCRDGYEPCVNEGICVTFHNGTGYCKCPEGFLGE
YCQHRDPCEKNRCQNGGTCVPQAMLGKATCRCALGFTGESCQYSTSHPCFMSRPCLNGGT
CHMLTRDTYECTCQTGFTGKLCQWTDACLSHPCANGSTCTTMANQFSCKCPAGFTGQKCD
IDINECEVPGQCLHGGTCLNLPGSYQCQCPQGFTGQNCDRPYVPCAPSPCVNGGTCQQTG
DFTFECNCLPGFEGTTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGDYGCVCVNGWTGADCSENIDDCAFASCTAGSTCIDRVASF
FCMCPEGKAGLLCHLDDACISNPCHKGALCNTNPLNGQYICTCPQGYRGADCTEDVDECA
MANSNPCEHAGKCVNTDGAFYCACQKGFAGSRCDMDINECHSDPCQNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPFCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSNPCLNDGRCIDLVNGYQCNCHPGTSGANCEINFDDCASNPCVNGICM
DGVNRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNSFRCLCPEGPHHPSCYSQ
VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCDVDKNECLSSPCQNGGTCNNLVNGYR
CTCKKGFKGFNCQVNIDECASNPCLNHGTCIDDISGYTCHCVLPYTGKNCQIVLAPCSPN
PCENDGVCKEAANFESYTCRCAPGWQGPQCTTDIDECVSKPCLNRGVCHNTQGSYMCECP
PGFSGMDCEEDVDDCIANPCQNGGSCVDGVNTFSCLCLLGFTGEKCQTDTNECLSEPCKN
GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPAGFTGP
FCLHEVNECDSQPCLNEGTCVDGVGTYRCTCPWGYTGRNCQTLVNLCSRSPCKNKGTCVQ
EKAVSRCLCPSGWTGAYCDVPSVSCEMAAAHKGVPVDRLCQNSGICTSVGNSHHCQCPPG
YSGSYCEEQLDECASNPCQHGSTCTDFIGGYRCECVSGYQGVNCEYEVDECQHQPCQNGG
TCIDLVNHFKCSCPPGTRGLLCEENIDDCAGGPRCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSSPCSVEGSLDCVQLTNDYMCVCRKAFTGRHCETFVDVCPQKPCLNGGTCA
VASNMPDGFICRCAPGFSGARCQSSCGQVKCRRGEHCVNTAAGPRCFCPNPQDCESGCSS
SPCQNGGSCSAQHQPPYYSCQCPPPFWGSHCEHYSAPTSIPAATCLSQYCADKARDGVCD
EPCNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNS
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQ
DARSFLRALGTLLHTNLRIKRDAQGELMVYPYYGEKSAAMKKHRMARRSLPSDQEQEVAG
SKVYLEIDNRQCVQDSEQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLIPPHTQFLY
LFAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSELWVDDEGPQPKKAKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPLG
KKPRRPNAKSAMPTSLPNLAKEAKDAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPTPMLATAAPPAPVHAQHALSFSNLHDMQPLAPGAGTVLPS
VSQLLSHHRIVPPGPGSVGGLGKLHPVSFPADWMNRVEMNETQYNEMFGMVLAPAEGTHP
GMAPQSRPPEGKQVPNPREPLPPIVTFQLVPKGSIGQPAGAAQPQPSCPPAVAGPLPAMY
QIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGTGGSQRGPGAHMS
EPARGNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtcccgcgccccgcccgcccgtgggtgctgctggcgctctggctgtgcggcgcg
acccccgcgcgcgcactgcaatgtcgggatggctatgagccctgtgtaaatgaaggaata
tgtgtcacctttcataatggcacaggatactgcaaatgtccagagggcttcttgggagaa
tattgccaacaccgagacccctgtgagaagaatcgctgccagaatggtgggacctgtgtg
cctcaggccatgttggggaaagccacatgtagatgtgccctgggattcacaggcgagagc
tgccagtactccacttcccacccctgcttcatgtctcgcccctgcctgaatggaggcact
tgtcacatgcttactcgggatacctatgagtgcacctgccaaactggttttacaggtaag
ctgtgccaatggactgatgcctgcctgtctcatccctgcgcaaatggcagtacctgtacc
accatggccaaccagttctcctgcaaatgcccggcgggcttcacagggcagaaatgtgac
attgacatcaacgagtgtgaagttccaggacagtgcctgcacggtggcacttgcctcaac
ctgccgggttcctaccagtgccagtgcccccagggcttcaccggccagaactgtgaccgg
ccctacgtgccctgcgcgccctccccctgtgtgaatgggggcacctgccagcagacgggt
gacttcacttttgaatgcaactgccttccaggttttgaaggaaccacctgtgagcggaat
atcgatgactgcccgaaccacaagtgtcagaatgggggcgtctgtgtagacggggtcaac
acttacaactgccgctgcccgcctcagtggacaggccagttctgcacggaggatgtagac
gagtgcctgctgcaacccaacgcctgccagaacgggggcacctgtaccaaccgcaatggg
gactacggctgtgtgtgtgtcaacggctggaccggagctgactgcagcgagaacatcgac
gactgtgccttcgcctcctgcactgcgggctccacctgcatcgaccgggtggcctccttc
ttctgcatgtgcccagaggggaaagccggtctcttatgtcatctggacgatgcgtgcatc
agcaacccctgccacaagggggcgctgtgtaacaccaaccctctgaatggccagtacatc
tgcacttgtccccagggctaccgaggagctgattgtactgaggatgtggacgaatgtgct
atggccaacagcaatccttgtgagcatgcaggaaagtgtgtgaacacagatggcgctttc
tactgtgcatgtcagaaggggtttgctgggtcacggtgtgatatggacatcaacgagtgc
cattcagacccctgccagaatgatgccacttgtctggataagattggaggttttacatgc
ctttgcatgccaggtttcaaaggtgtgcattgtgagctggagataaatgaatgtcagagc
aacccctgtgtgaacaacgggcagtgtgtggacaaggtcaatcgcttccagtgtctgtgt
ccgcctggtttcactgggccattttgccagattgacattgatgactgctccagtactccg
tgtctgaacggggccaagtgtatcgatcacccgaatgggtatgagtgccagtgtgccaca
ggatttactggtgtgttgtgtgaggagaacattgacaactgtgaccctgatccttgccac
catggccagtgccaggatggcattgattcctacacctgcatctgcaacccagggtacatg
ggtgccatctgcagcgaccagatagacgaatgttatagcaacccctgcttgaatgacggc
cgctgcatcgacctggtgaacggctaccagtgcaactgccaccccggcacgtccggtgct
aactgtgaaatcaattttgatgactgtgccagtaacccttgtgtcaacggcatctgcatg
gacggtgttaaccggtacagctgtgtctgctccccggggttcacaggacagagatgcaac
attgacattgatgagtgtgcttccaatccctgccgcaagggcgccacctgcatcaatgat
gtgaacagtttccgctgcctctgcccagaggggccccaccaccccagctgctactcacag
gtgaacgagtgtctgagcaatccctgcatccacggaaactgcactgggggcctcagcggg
tacaaatgcctctgtgatgcaggttgggtcggtgtcaactgtgacgtggataaaaatgaa
tgcctgtcgagtccatgccagaacggaggaacttgtaacaacctggtgaacgggtacagg
tgtacttgcaagaagggctttaaaggtttcaactgccaggtgaacattgacgaatgtgct
tcgaatccatgcctgaaccatggaacctgcatcgatgacataagtggctacacgtgtcat
tgcgtactgccgtacacgggcaagaactgtcagatcgtgctggctccttgttccccaaac
ccgtgtgagaatgatggcgtttgtaaagaggctgccaattttgagagttacacctgtcgg
tgtgccccaggctggcaaggtccacagtgtaccacggacattgacgagtgtgtctccaag
ccctgcctgaaccgtggcgtctgccacaacacccagggcagctacatgtgtgagtgtccc
ccgggcttcagcggtatggactgtgaggaggacgtcgatgactgcatcgccaatccttgc
cagaatggagggtcctgtgtcgacggagtaaatactttctcctgcctgtgtcttctgggc
ttcactggggagaagtgtcagaccgacacgaatgagtgtttgagtgagccgtgtaagaat
gggggaacctgctctgactatgtcaacagttacacttgcaagtgtcaggcaggatttgat
ggcgtccactgtgagaacaacattgacgaatgcacggagagctcctgtttcaatggcggc
acctgtgtggatgggattaactccttctcttgcctgtgccctgcgggcttcactggcccc
ttctgtctccacgaggtcaatgagtgtgactcccagccatgcctgaatgaaggaacctgt
gtggatggtgtgggcacctaccgctgcacctgcccctggggctacaccggcaggaactgt
cagaccctggtgaacctttgcagccggtctccgtgtaagaacaaaggcacttgtgtgcag
gaaaaggcagtgtctcggtgcctctgtccctcggggtggaccggagcctactgtgacgtg
cccagcgtctcctgtgagatggcggccgcccacaaaggggtgcctgtggaccgcttgtgc
cagaattctggcatctgcacgtcagtcggcaactcgcaccactgccagtgtcccccgggc
tactcggggagctactgtgaggagcagctggacgagtgcgcgtccaacccctgccagcac
ggctccacctgcaccgacttcatcggcgggtaccgatgcgagtgtgtctcggggtatcag
ggcgtcaactgtgagtatgaagtggacgagtgccagcaccagccctgccagaatggaggc
acctgcattgacctcgtgaaccacttcaagtgctcctgcccacctggcactcggggcctg
ctctgcgaagagaacatcgacgactgtgccgggggtcctcgctgcctgaatgggggtcag
tgtgtggaccggattggtggctacagctgccgctgcttgcccggctttgctggcgagcgc
tgtgagggggacatcaacgagtgcctctccagcccctgcagcgtggagggcagcctggac
tgcgtccagctcaccaacgactacatgtgtgtgtgccgcaaggccttcaccggtcgccac
tgtgaaactttcgtcgatgtgtgtccccagaagccctgcctgaatggagggacttgcgct
gtggccagtaacatgccagatggttttatttgtcgttgtgctccgggattctcaggggca
agatgccagagcagctgtgggcaggtgaagtgccgaagaggggagcactgtgtcaacacg
gccgccgggccgcgctgcttctgccccaacccccaggactgcgagtcgggctgttctagc
agcccctgccagaacgggggcagctgcagcgcccagcaccagcctccctactactcttgc
cagtgccccccgccattctggggcagccactgcgagcactactccgcccccaccagcatc
cctgcggccacctgtctgagccagtactgtgctgacaaggcgcgggacggtgtctgcgac
gagccctgcaacagccacgcctgccagtgggatgggggcgactgttcgctcaccatggag
aacccgtgggccaactgctcctcccccctgccctgctgggactacatcaacaaccagtgc
gacgagctgtgcaacacggccgagtgcctgttcgacaactttgaatgccaggggaacagc
aagacgtgcaagtatgacaaatactgtgcagaccacttcaaagacaaccactgtgaccag
ggctgcaacagtgaagagtgcggctgggacgggctggactgcgctgctgaccggccggag
aacctggccgagggcacgctggtcatcgtggtgctgatgccgcccgagcagctgctgcag
gatgcccgcagcttcttgagggcgctgggcaccctgctgcacaccaacctgcgcatcaag
cgggacgcgcagggggagctcatggtctacccctactacggcgagaagtccgctgccatg
aagaagcacaggatggcacgcaggtcccttcccagtgaccaagaacaggaggtggctggc
tccaaggtctatctggagatcgacaatcgacagtgtgtgcaggactccgaacagtgcttc
aagaacaccgacgcggccgcagcgctcctggcgtctcacgctattcagggcaccctgtca
tacccactggtgtctgtcgtcagtgagtccttgattccacctcacacacagttcctctac
ctgtttgctgtcgctgtggtcatcatcctgtttatcatcctgctgggggtcatcatggca
aagcggaagcgcaaacacggttccctgtggctgcctgaaggcttcaccctccgccgagac
tccagtaaccacaagcgccgggagcccgtggggcaggacgccgtggggctgaaaaatctc
tccgtgcaagtctcagaggctaacctaattggttctggaacaagcgaactttgggttgac
gatgaagggcctcagccaaagaaagccaaggctgaagatgaagctttactctcagaggag
gatgaccccattgaccgacgtccctggacccagcagcacctggaagctgcagatattcgt
aggacgccgtcattggctctcactcctccccaggcggagcaggaggtggacgtgctggac
gtgaatgtccgtggtccagacggatgcaccccgctgatgctggcttctcttcggggtggc
agctcagatctgagtgatgaagatgaagacgccgaggactcttctgccaacatcatcaca
gacctggtctaccagggcgccagtctccaggcccagacagatcggactggggagatggcg
ctgcacctggccgcccgctactccagggctgacgccgccaagcgcctcctcgacgctgga
gcagatgccaatgctcaggacaacatgggccgctgccctctccatgctgcggtggccgcc
gatgcccaaggagtcttccagattctgattcgtaaccgagtaacagatctcgatgccagg
atgaatgatggcaccacacctctgatcctggctgcccgcctggctgtggagggaatggtc
gcagaactgatcaactgccaggcagatgtgaacgcggtggatgaccacggaaaatctgct
cttcactgggcagcagctgtcaataacgtggaggcaacccttttgctgttgaaaaatggg
gccaaccgagacatgcaggacaacaaggaggaaacgcctctgttcctcgccgcccgcgag
gggagctacgaagcggccaagatcctgctggaccactttgcgaaccgggacatcacagac
cacatggatcgcctcccgcgggacgtggctcgggaccgcatgcaccacgacatcgtgcgc
ctgctggatgagtacaacgtgacccccagcccgccgggcaccgtgctcacttccgcgctc
tccccagtcatctgtgggcccaacaggtctttcctcagcctgaagcacaccccgctgggc
aagaagccacggcgacccaacgccaagagcgccatgcccacgagcctgcccaacctcgcc
aaggaggccaaagatgccaagggcagccggcggaagaagtccctgagtgacaaggggcag
ctgtcggagagctcggtgactctgtcccccgtcgactccttagagtccccccatacctat
gtgtctgacaccacctcctcccccatgatcacatcccctgggatcctccaggcctcgccc
accccgatgctggccaccgccgcccccccggcccccgtgcacgcccagcacgcgctgtct
ttctctaacctccacgacatgcagcccctggctcccggggccggcacggtgctgccctcg
gtgagccagctgctcagccaccaccgcatcgtcccgcccggccccgggagcgtgggcggc
ctggggaaactccacccggtctcgttcccagccgactggatgaaccgtgtggagatgaat
gagacgcagtacaacgagatgtttggcatggtcctggccccggctgaggggacccaccct
ggcatggccccccagagccggccgcccgaagggaagcaggtccccaacccccgagagccc
ttgcccccaatcgtgactttccagctggtccccaaaggcagcatcggccagcccgcaggg
gctgcccagccccagcccagctgccctcctgccgttgccggccccctccccgccatgtat
cagatcccagaaatggcgcgtttgcccagcatggcgtttcccactgccatgatgccacag
caggacgggcaggtggcgcagaccatcctcccggcctaccatcctttccccgcctccgtg
ggcaagtaccccacgcccccatcgcagcatagctatgcgtcctccaacgcggccgagcgg
acgcccagtcatagcggtcacctccagggcgagcacccctacctgacaccgtccccagag
tctcccgaccagtggtcgagctcttcgccccactccgcttccgactggtcggatgtgacc
accagcccgactcccggcggcacgggaggcagtcagcgggggcccggggcacacatgtcg
gagccagcacgcgggaacatgcaggtctacgcatga
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integrated database retrieval system
