Sorex fumeus (smoky shrew): 130031339 Help Entry 130031339         CDS       T10594                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00230   Purine metabolism sfum01100   Metabolic pathways sfum01522   Endocrine resistance sfum04015   Rap1 signaling pathway sfum04020   Calcium signaling pathway sfum04022   cGMP-PKG signaling pathway sfum04024   cAMP signaling pathway sfum04062   Chemokine signaling pathway sfum04072   Phospholipase D signaling pathway sfum04081   Hormone signaling sfum04082   Neuroactive ligand signaling sfum04114   Oocyte meiosis sfum04211   Longevity regulating pathway sfum04213   Longevity regulating pathway - multiple species sfum04261   Adrenergic signaling in cardiomyocytes sfum04270   Vascular smooth muscle contraction sfum04371   Apelin signaling pathway sfum04540   Gap junction sfum04611   Platelet activation sfum04713   Circadian entrainment sfum04714   Thermogenesis sfum04723   Retrograde endocannabinoid signaling sfum04724   Glutamatergic synapse sfum04725   Cholinergic synapse sfum04727   GABAergic synapse sfum04740   Olfactory transduction sfum04750   Inflammatory mediator regulation of TRP channels sfum04911   Insulin secretion sfum04912   GnRH signaling pathway sfum04913   Ovarian steroidogenesis sfum04914   Progesterone-mediated oocyte maturation sfum04915   Estrogen signaling pathway sfum04916   Melanogenesis sfum04918   Thyroid hormone synthesis sfum04921   Oxytocin signaling pathway sfum04923   Regulation of lipolysis in adipocytes sfum04925   Aldosterone synthesis and secretion sfum04926   Relaxin signaling pathway sfum04927   Cortisol synthesis and secretion sfum04928   Parathyroid hormone synthesis, secretion and action sfum04934   Cushing syndrome sfum04935   Growth hormone synthesis, secretion and action sfum04962   Vasopressin-regulated water reabsorption sfum04970   Salivary secretion sfum04971   Gastric acid secretion sfum04972   Pancreatic secretion sfum04976   Bile secretion sfum05032   Morphine addiction sfum05163   Human cytomegalovirus infection sfum05166   Human T-cell leukemia virus 1 infection sfum05200   Pathways in cancer sfum05207   Chemical carcinogenesis - receptor activation sfum05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:sfum00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     130031339 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     130031339 (ADCY3)    04371 Apelin signaling pathway     130031339 (ADCY3)    04020 Calcium signaling pathway     130031339 (ADCY3)    04072 Phospholipase D signaling pathway     130031339 (ADCY3)    04024 cAMP signaling pathway     130031339 (ADCY3)    04022 cGMP-PKG signaling pathway     130031339 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     130031339 (ADCY3)    04081 Hormone signaling     130031339 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     130031339 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     130031339 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     130031339 (ADCY3)    04062 Chemokine signaling pathway     130031339 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     130031339 (ADCY3)    04923 Regulation of lipolysis in adipocytes     130031339 (ADCY3)    04912 GnRH signaling pathway     130031339 (ADCY3)    04913 Ovarian steroidogenesis     130031339 (ADCY3)    04915 Estrogen signaling pathway     130031339 (ADCY3)    04914 Progesterone-mediated oocyte maturation     130031339 (ADCY3)    04921 Oxytocin signaling pathway     130031339 (ADCY3)    04926 Relaxin signaling pathway     130031339 (ADCY3)    04935 Growth hormone synthesis, secretion and action     130031339 (ADCY3)    04918 Thyroid hormone synthesis     130031339 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     130031339 (ADCY3)    04916 Melanogenesis     130031339 (ADCY3)    04925 Aldosterone synthesis and secretion     130031339 (ADCY3)    04927 Cortisol synthesis and secretion     130031339 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     130031339 (ADCY3)    04270 Vascular smooth muscle contraction     130031339 (ADCY3)   09154 Digestive system    04970 Salivary secretion     130031339 (ADCY3)    04971 Gastric acid secretion     130031339 (ADCY3)    04972 Pancreatic secretion     130031339 (ADCY3)    04976 Bile secretion     130031339 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     130031339 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     130031339 (ADCY3)    04727 GABAergic synapse     130031339 (ADCY3)    04725 Cholinergic synapse     130031339 (ADCY3)    04723 Retrograde endocannabinoid signaling     130031339 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     130031339 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     130031339 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     130031339 (ADCY3)    04213 Longevity regulating pathway - multiple species     130031339 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     130031339 (ADCY3)    04714 Thermogenesis     130031339 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130031339 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     130031339 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     130031339 (ADCY3)    05163 Human cytomegalovirus infection     130031339 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     130031339 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     130031339 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     130031339 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     130031339 (ADCY3) Enzymes [BR:sfum01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      130031339 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Motif Other DBs NCBI-GeneID:  130031339 NCBI-ProteinID:  XP_055978542 LinkDB All DBs Position Unknown AA seq 1141 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGAGRTHEISVRNSGSCLCLPRFMRLTFVPE SLESLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFAGDKLAPLLVAAVGLVLDII LFVLCKKGLLPDRVSRKVVPYLLWLLITAEIFSYLGLNFARAHALSDTVGWQAFFVFSYF ITLPLSLSPIVIISVLSCVLHTVVLAVTVAQQQQDRLNGTLLLREILANVFLYLGAIIAG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFTTMYMYRHENVSILFADIVGFTQLSSGCSAQELVKLLNQLFASFDKLAARYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAIAYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD YLDEKGIETYLVIASGPYVKKPQNGTVRRGRVPNGLPTASRPNTPILIDTDTKEPNGDAH TEEPEEQETEADNPAFPNPRRRLRLQDLADRVADASQDEHELNQLLNEALLERESAQVVK KRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTALVETLIDPWLMTNYVTF VVGEVLLLVLTICSLASIFPRNFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDM LSCLQYYTGTGNVTAGPEVVDGCVQNPKYYNYVAVLSLVACIMLVQVSHMVKLTLMLLVS GAVAVVNIYAWRPIFDDYDHRRFQENDFPMVALEKMQVLPAPALNGTDSLPLVPSKYSMT VMILFMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARH FLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEEAINNGGIECLRFLNEIISDFDSLL DNPKFRVITKIKTIGSTYMAASGVNPDINTNGYTSSNKDEKSDKERWQHLADLADFALAM KDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNI QVVEETQIILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQVVDN P NT seq 3426 nt NT seq  +upstreamnt  +downstreamnt atgccgcggaaccagggcttctccgaccccgagtactcggcggagtactctgccgagtac tcggtgagcctgccctctgaccccgaccgcggggcgggccggacccatgagatctccgtg cgcaactcggggtcgtgcctgtgcctgccccgcttcatgcggctgaccttcgtgcccgag tccctggagagcctctaccagacctacttcaagcggcagcgccacgagacgctgctggtg ctggtggtcttcgccgcccttttcgactgctacgtggtggtcatgtgcgccgtggtcttc gccggcgacaagctggcgccgctgctggtggccgccgtggggctggtgctggacatcatc ctcttcgtgttgtgcaagaaagggctgctccccgaccgcgtgagccgcaaggtggtgccg tacctgctgtggctgctgatcacggccgagatcttctcctatctgggcctgaacttcgcc cgcgcgcacgcgctcagcgacacggtgggctggcaggccttcttcgtcttctcctacttc atcacgctgccgctcagcctcagccccatcgtcatcatctccgtgctgtcctgcgtgctg cacacagtcgtcttggcggtcaccgtggcccagcagcagcaggacaggctcaatgggacc ctcttgctgagggagatcctggccaacgtcttcctatacctgggcgccatcatcgcgggc atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctc tccatcctgcccaaacacgtggccgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcacaaccatgtacatgtaccgccacgagaacgtcagcatc ctcttcgcggacatcgtgggcttcacccagctgtcgtccggctgcagcgcgcaggagctg gtgaagctgctcaaccagctcttcgccagcttcgacaagctggcggctaggtaccaccag ctgcgcatcaagatcctgggcgactgctactactgcatctgcgggctgcccgactaccgc gaggaccacgccgtctgctccatcctcatggggctcgccatggtcgaggccatcgcgtac gtgcgcgagaagaccaagacgggggtggacatgcgtgtgggggtgcacacgggcaccgtg ctgggcggcgtcctgggccagaagcgctggcagtacgacgtgtggtccacagacgtgact gtggccaacaagatggaggccgggggcatcccagggcgcgtgcacatctcccagagcacc atggactgcctgaagggcgagttcgacgtggaacccggggacggcggcagccgctgcgac tacctggacgagaagggcatcgagacctacctggtcatcgcgtcggggccctacgtgaag aaaccccagaatggcacggtgaggcgtgggcgagtgcccaatggcttgcccaccgcctca aggcccaacaccccgatcctcatcgataccgacaccaaggagcccaatggcgatgcccac acggaggagccagaggagcaggagactgaggccgacaaccccgcctttcccaatccccgc cggaggctgcgcctgcaggacctggctgaccgcgtagcggatgcctctcaggacgagcac gagctcaaccagctcctcaatgaggcgctactggagcgcgagtctgcgcaggtggtgaag aagagaaacaccttcctcctgtccatgcgcttcatggaccccgaaatggagacgcgttac tcggtggagaaggagaaacagagcggggctgccttcagctgctcctgcgtggtcctgttc tgcacggcgctcgtggagaccctcatcgacccctggctcatgactaactatgtgaccttt gtggtgggggaggttctgctcctggtcctgaccatctgctcgctggcttccatctttccc cggaactttcctaagaagctcgtggccttttccacttggattgaccggacccgctgggcc aggaacacgtgggccatgttagccatcttcatcctggtcatggccaacgtggtggacatg ctgagctgcctccagtactacacggggaccggcaacgtcaccgcaggcccggaggtggtg gatggctgtgtgcagaaccccaagtattacaactacgtggccgtgctgtcgctggtggcc tgcatcatgctggtgcaggtcagccacatggtgaagctcacgctcatgctgctggtctcg ggcgccgtggccgtcgtcaacatctatgcctggcgccccatcttcgacgactacgaccac cggcgcttccaagagaacgacttccccatggttgccctggagaagatgcaggttcttcct gccccagcactcaacggcaccgacagcctgcccctggtgccgtccaagtactccatgacc gtgatgatcctcttcatgatgctcagcttttactacttctcccgccacgtggagaaactg gcgcggacactgttcctgtggaaaattgaggtccatgaccagaaggagcgggtctatgaa atgcgacgctggaatgaggccttggtcaccaacatgctgcctgagcacgtggcccgccac ttcctgggctccaagaagagggacgaggagctctacagccagtcctacgacgagattgga gtcatgtttgcctccctgcccaacttcgccgacttctacacagaggaggccatcaacaac ggcggcatcgagtgtctgcgcttcctcaacgagatcatctcggattttgactctctcctg gacaaccccaaattccgggtcatcaccaagatcaagaccattggcagcacctatatggca gcttctggagtgaacccagatatcaacaccaatggctacacaagttccaacaaggacgaa aagtcggacaaggagcgctggcagcacctggcggacctggcggacttcgcgctggccatg aaggacacgctcacgaacatcaacaaccagtccttcaacaacttcatgctgcgcatcggc atgaacaaaggcggggtgctggccggggtcatcggggcccggaagccacactatgacatc tggggcaataccgtcaacgtggccagcaggatggagtccacgggagtcatgggcaacatt caggtggtggaggagacgcagatcatcctgcgcgagtacggcttccgcttcgtgcggcgc gggcccatcttcgtcaagggcaagggcgagctgctgaccttcttcctgaagggccgtgac aagccggccgccttccccaacgggtcctcggtgacgctgccccaccaggtggtggacaac ccctga

DBGET integrated database retrieval system