Sorex fumeus (smoky shrew): 130032041 Help Entry 130032041         CDS       T10594                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00010   Glycolysis / Gluconeogenesis sfum00620   Pyruvate metabolism sfum01100   Metabolic pathways sfum01200   Carbon metabolism sfum01230   Biosynthesis of amino acids sfum04910   Insulin signaling pathway sfum04930   Type II diabetes mellitus sfum04932   Non-alcoholic fatty liver disease sfum04950   Maturity onset diabetes of the young Module sfum_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate sfum_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:sfum00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     130032041 (PKLR)    00620 Pyruvate metabolism     130032041 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     130032041 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     130032041 (PKLR)    04950 Maturity onset diabetes of the young     130032041 (PKLR)    04932 Non-alcoholic fatty liver disease     130032041 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:sfum04147]     130032041 (PKLR) Enzymes [BR:sfum01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      130032041 (PKLR) Exosome [BR:sfum04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    130032041 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  130032041 NCBI-ProteinID:  XP_055979601 LinkDB All DBs Position Unknown AA seq 574 aa AA seqDB search MSTQENAQHQPLWSWVSKSQKDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQRQQ LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS HGSHEYHAQSIANVREAVESLATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVELVKG SSVLVTVDPEFRTRGDAKTVWVDYPNIVRVVPVGGHIYIDDGLISLAVRKIGSRGLETEV ENGGTLGSRKGVNLPGAQVDLPGLSEQDARDLQFGVEHGVDIIFASFVRKASDVVAVRSA LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVQM QHAIAREAEAAVYHRQLFEELRRAAPLSRDLAEVTAIGAVEAAFKCCAAAIIVLTKTGRS AQLLSRYRPRAAVIAITRSAQAARQAHLCRGVFPLLYRDPPEPVWADDVDRRVQFGIDSG KLRGFLHTGDLVIVVTGWRPGAGYTNIMRVVNVS NT seq 1725 nt NT seq  +upstreamnt  +downstreamnt atgtcgacccaggagaacgcacaacaccagccactctggtcatgggtctctaagtcccag aaggacttagcaaagtccatccttatcggggctccaggagggccagcgggatacctgagg cgggccagcgtggcacagctgacccaggagctgggcacagcattcttccagcggcaacag ttgccggcggccatggcagacacctttctggagcacctgtgcctgctggacatcgactct gagcctgtggccgctcgcagcaccagcatcattgcaacaatcgggcccgcatcgcgctcg gtggagcgcctcaaggagatgatcaaggccggcatgaacatcgcgcggctcaacttctcc cacggctcccacgagtaccacgctcagtccatcgccaacgtccgggaggcggtggagagc ctggccacctccccgctcagctaccgcccggtggccatcgccctggacaccaagggaccg gagattcgcaccggggtcctgcaggggggccctgagtcggaagtggagctggtgaagggc tcctcggtgctggtgacggtggacccggagttccgaacgcggggggacgcgaagaccgtg tgggtggactaccctaatatcgtccgggtggtgccggtggggggccacatctacatcgac gacgggctcatctccctcgcggtcaggaaaatcggctccagagggctggagaccgaagtg gagaacggaggcaccctaggcagccggaagggggtgaacctgcctggagcacaggtggat ctgcctgggctgtctgagcaagacgctcgcgaccttcagttcggggtggagcacggcgtt gacatcatctttgcgtccttcgtccggaaagccagcgatgtggttgctgtccggtctgcc ctagggcctgaaggtcagggcatcaagatcattagcaaaatcgagaaccacgaaggtgtg aagagatttgatgaaattctggaggtgagcgacggcatcatggtggcccgcggggacctg ggcattgagatcccagccgagaaggtctttctggctcagaagatgatgatcggtcgttgc aacttggcgggcaagcccgttgtctgtgccacacagatgctggagagcatgatcaccaag ccacggcccacacgggcagagaccagcgacgtggccaacgcagtgcttgatggggcagac tgcatcatgctctcgggtgagaccgccaagggcagctttcctgtggaggctgttcagatg cagcacgcgatcgcacgggaggccgaggccgctgtgtaccaccggcagctgtttgaggaa ctgcgccgggcagccccgttgagccgagacctggctgaggtcactgccattggtgccgtg gaggctgccttcaagtgctgtgctgcagccatcattgtgttgacgaaaactggccgctct gcccagcttctgtcccggtaccgccctcgggcagccgtcattgccatcacacgctctgcc caggcagctcgccaggcacacctgtgccgaggagtcttccccttgctctaccgtgatcct ccagagcccgtgtgggccgacgacgtggaccgccgggtgcagttcggcattgacagtgga aagctgcgtggcttcctccacacgggagacctggtgatcgtggtgactggctggcggccc ggcgctggctacaccaacatcatgcgagtagtgaatgtgtcctga

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