Sorex fumeus (smoky shrew): 130035025 Help Entry 130035025         CDS       T10594                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00220   Arginine biosynthesis sfum00330   Arginine and proline metabolism sfum01100   Metabolic pathways sfum04020   Calcium signaling pathway sfum04066   HIF-1 signaling pathway sfum04146   Peroxisome sfum04371   Apelin signaling pathway sfum04926   Relaxin signaling pathway sfum05010   Alzheimer disease sfum05014   Amyotrophic lateral sclerosis sfum05022   Pathways of neurodegeneration - multiple diseases sfum05133   Pertussis sfum05140   Leishmaniasis sfum05142   Chagas disease sfum05145   Toxoplasmosis sfum05146   Amoebiasis sfum05152   Tuberculosis sfum05200   Pathways in cancer sfum05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:sfum00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     130035025 (NOS2)    00330 Arginine and proline metabolism     130035025 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     130035025 (NOS2)    04066 HIF-1 signaling pathway     130035025 (NOS2)    04020 Calcium signaling pathway     130035025 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     130035025 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     130035025 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130035025 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     130035025 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     130035025 (NOS2)    05152 Tuberculosis     130035025 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     130035025 (NOS2)    05145 Toxoplasmosis     130035025 (NOS2)    05140 Leishmaniasis     130035025 (NOS2)    05142 Chagas disease     130035025 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     130035025 (NOS2)    05014 Amyotrophic lateral sclerosis     130035025 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     130035025 (NOS2) Enzymes [BR:sfum01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      130035025 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 NAD_binding_6 Motif Other DBs NCBI-GeneID:  130035025 NCBI-ProteinID:  XP_055982486 LinkDB All DBs Position Unknown AA seq 1157 aa AA seqDB search MREGLGSACEAARPRLCRLFRRILGSKPACSPRGTSAATQDDPEGPNSLGHKLRNESPQP HSGTEKSPEPPVKLDEPLVTSPRYVKIKNWGSGASFQDTLHHKAKRDLACKSKSCHGAIM NPKSLIIGPKDKPTSPDELLPQAIEFINQYYDSFKEAKIEAHLARVEAVTKEIEITGTYQ LTGDELIYATKQAWRNAPRCIGRIQWANLQVFDARSCSTAQEMFEHICRHIRYATNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTIRGDPACVEFTQLCIDLGWKPKYG RFDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKYEWFQELALKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLTSLWKDRAVIEINI AVLHSFQKQNVTILDHHSATESFMKYMQSEYRARGGCPADWIWLVPPISGSITPVFHQEM ISYVLSPFFYYQVEAWKTHIWADGKRRPRRREIHFRILVRAVLFASVLMRKSMASRVRVT ILFATETGRSETLARDLGALFSCAFNPQVLCMDEYQLDRLEEERLLLVLTSTFGNGDAPS NGQKFKKSLFMLKKLTNKFRYAVFGLGSSMYPQFCAFAHDLDQKLSLLGASQLSPTGEGD ELSGQEEAFRSWAVQTFKAACESFQVRGKQHIEIPKRYSCNVDWEPQRYRLVQDSQPWDL SKALSSVHAKNVVTMRLKSLQPLQGPKSSRSVLLVELSCKDCPGLSYLPGDHLGVFPCNQ PELVQGILERLADGPDPHQPVSLETLDDKGSYWVRDQRLPPCSLSQALTCFLDITTPPSQ QLLQKLALLAAAKEERQQLEELSQPSEYSKWKLAHSPTFLEVLGAFPSVRVSATFVLSQL PLLKARYYSISSAAAHVPCELHLTVAVLTYRTQAGQGPLHHGVCSTWLSSLKAGDPVPCF LQSANNFQLPQDPSQPCILVGPGTGIAPFRSFWQQRLYEAEHKGLQGGRLTLVFGCRHPD QDHLYREEMLEMVRKGVLHEVHTAYSRLPGQPKVYVQDVLRQRLAGEVLRVLLEERGHIY VCGDVRMARDVGLTLRQLVAGALGLSEEQVEDYFFQLKSQERYHEDIFGAVLPRGQRKDE AIEQPSNPRAPVTSTRS NT seq 3474 nt NT seq  +upstreamnt  +downstreamnt atgcgcgaggggctgggcagcgcgtgcgaggccgcccggccccggctgtgccggctcttc cgcaggatcctcgggtccaagcccgcctgcagcccccgcggaaccagtgcagcaacacag gatgacccagagggcccaaacagccttggccacaagctccggaatgagtccccacagccc cactcaggcacagaaaagtctccagaacccccagtcaagttggatgagcccctggtgacc agccctcgatatgtgaagatcaaaaactggggcagtggggccagtttccaagacacactt caccacaaagctaaaagggatcttgcttgcaagtccaaatcttgccacggggccatcatg aacccaaagagtttgatcattggacccaaggataagcctacctcccccgatgagcttcta cctcaagcgattgaatttatcaaccagtattacgactccttcaaagaggcaaaaatagag gcacatctggcccgagtggaagcggtaacaaaggagatagaaataacaggaacctaccag ctgacgggggatgagctcatctacgccaccaagcaggcctggcgcaacgccccccgctgc atcgggaggatccagtgggccaacctccaggtcttcgatgcccggagctgttctactgct caggaaatgttcgagcacatctgtagacacatccgttatgccaccaacaacggcaacatc aggtcggccatcacggtgttcccgcagcggagcgacgggaagcatgacttcagggtgtgg aatgcgcagctcatccgctatgccggctaccagatgcccgacggcacgatccgcggggac cccgcctgcgtggaattcacccagctgtgcatcgaccttgggtggaagcccaagtatggg cgctttgatgtggtgccgctggtcctgcaagccgatggccgtgacccggagctcttcgaa atcccgcctgacctggtgcttgaggtgcccatggagcatccaaagtatgagtggttccag gagctggcactgaagtggtatgccctgcctgcagtggccaatatgttgctggaagtgggt ggccttgagttcccagggtgtcctttcaacggatggtacatgggcacagagatcggggtc cgggacttctgtgatgtccagcgctacaacatcctggaggaagtgggccgaaggatgggc ctggagacacacaagctgacctccctctggaaagaccgggctgtgattgagatcaacatc gccgtgctccatagtttccagaagcaaaatgtcaccatcctggaccaccactcagccaca gagtccttcatgaagtacatgcagagcgagtaccgggcgcgtgggggctgtccggccgac tggatttggctggttcccccaatttctggaagcattacccctgtgttccaccaggagatg ataagctatgtcttgtcccctttcttctactaccaggtggaggcctggaaaacccacatc tgggcagacgggaagcggaggccccgtagaagagagattcacttccgaatcttggttagg gctgtgctcttcgcctctgtcctcatgcgtaagtccatggcatctcgggtcagagtcaca atcctctttgcaacagagacggggcgatcggagacgctggcccgggacctgggggccttg ttcagctgcgccttcaacccccaggttctctgcatggacgagtaccagctggacaggctg gaggaggagcgactgctgctggtgttgacaagcacattcgggaacggagacgcccccagc aatgggcagaaattcaagaaatccctcttcatgctgaaaaagctgaccaacaagttcagg tacgccgtgtttggcctcggctccagcatgtaccctcagttctgcgcctttgctcatgac cttgaccagaagctgtctctcctgggagcatctcagctcagccccaccggagaaggggac gagctcagcgggcaggaggaggccttccgcagctgggccgtgcaaaccttcaaggcggcc tgtgagagcttccaagtccgaggcaaacaacacattgagatccccaagcgctacagctgc aacgtggactgggaaccacagcgctacaggctggtgcaggactcacagccttgggacctc agcaaagccctgagcagcgtgcacgccaagaacgtggtgaccatgaggctcaaatctctg cagcccctccaaggcccgaaatccagccgctccgtcctcctggtggaactttcctgcaag gactgccctggcctaagctacctgcctggagaccacctcggggttttcccatgcaaccag ccagagctggtccagggcatcttggaacgcctggcagatggccctgatccccaccaacct gtgagcctggagaccctcgacgataaaggaagctactgggtcagagaccagcggctacct ccctgctccctcagccaggccctcacctgcttcctggacatcaccacgccccccagccaa cagctgctccagaagctggcactgctcgctgcggccaaggaggaaaggcagcagctggag gagttgagccagccctcagagtacagcaagtggaagctcgcccacagccccacgttcctg gaggtactgggggcgttcccgtccgtgcgggtgtccgccacctttgtgctctcgcagctc ccgctgctgaaagcccgctactactccatcagctctgcagccgcgcacgtgccctgtgag ctccacctgaccgtggccgttctcacgtaccgcacccaagccggccagggtcccctgcat catggcgtctgcagtacgtggctcagcagcctgaaggctggagacccagtgccctgcttt ctgcaaagtgccaacaacttccagctaccccaggacccctctcaaccttgcatccttgtc gggcctggcacgggcatcgccccctttcgcagtttctggcaacagcggctctatgaagct gaacacaaagggctccagggtggtcgcctgaccctggtgtttggatgccgccacccagac caggaccacctctatcgagaggagatgctggagatggtccgaaagggggtgctgcatgag gtgcacacagcctactcacgcctgcctggccagcccaaggtctatgtgcaggacgtcctg cgacagcggctggcaggtgaggtgctccgcgtgctacttgaggagcgaggacacatctac gtctgcggggatgtgcgcatggcccgcgacgtgggcctcaccttgaggcagctggtggcc ggcgccctgggcctgagtgaggagcaggtggaggattatttcttccaactcaagagccag gagcgttaccatgaggatatctttggtgctgtgcttccccgtgggcagaggaaggacgag gccatagagcagcccagcaaccccagagctccagtcaccagcacaagaagttga

DBGET integrated database retrieval system