KEGG T10594: 130037554

Sorex fumeus (smoky shrew): 130037554

Entry

130037554         CDS       T10594

Symbol

PLCD1

Name

(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

K05857

phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]

Organism

sfum Sorex fumeus (smoky shrew)

Pathway

sfum00562

Inositol phosphate metabolism

sfum01100

Metabolic pathways

sfum04020

Calcium signaling pathway

sfum04070

Phosphatidylinositol signaling system

sfum04919

Thyroid hormone signaling pathway

sfum04933

AGE-RAGE signaling pathway in diabetic complications

Module

sfum_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Brite

KEGG Orthology (KO) [BR:sfum00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    130037554 (PLCD1)
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    130037554 (PLCD1)
   04070 Phosphatidylinositol signaling system
    130037554 (PLCD1)
09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    130037554 (PLCD1)
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    130037554 (PLCD1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130037554 (PLCD1)
Enzymes [BR:sfum01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     130037554 (PLCD1)
Membrane trafficking [BR:sfum04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    130037554 (PLCD1)
Endocytosis
  Macropinocytosis
   Phospholipase C
    130037554 (PLCD1)

SSDB

Motif

Pfam:

PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 PH_12 PH EF-hand_7 EF-hand_15 EF-hand_6 EF-hand_1 WHD_MCM8 EF-hand_5 REV1_C TEP1_N

Other DBs

NCBI-GeneID:

130037554

NCBI-ProteinID:

XP_055985391

LinkDB

Position

Unknown

AA seq 777 aa
MQCLGIRRRSRSQELYLQEQSRKVAALNGQRLGLQGDEDLQALLKGSQLLKVKSSSWRRE
RFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQDVRMGHRTEGLEKFARDVPDDRCFSI
VFKDQRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNK
MSFKELQNFLKELNIQVDDNYARKIFRECDHSQTDSLEDEEIEVFYKMLTQRAEIDRIFA
EATGSGETMSVGQLVTFLQHQQREEEAGPALALSLIERYEPSETAKAERQMTKDGFLMYL
LSADGSAFSLAHRRVYQDMNQPLSHYLVSSSHNTYLLEDQITGPSSTEAYIRALCKGCRC
VELDCWDGPNLEPVIYHGYTFTSKIFLCDVLRAIRDYAFKASPYPVILSLENHCSLEQQR
VMASHLRSILGPLLLDQPLEGVTSSLPSPEQLKGKILLKGKKLGGLVPPGGEAGPEATVS
DEDEAAEMEDEAVRSRVQHKPKEDKLRLAKELSDIVIYCKSVHFGGFSSPGSPEQAFYEM
VSFSENRAVRLLQESGNSFVRHNVNHLSRIYPAGRRTDSSNYHPVDMWNGGCQIVALNFQ
TPGPEMDVYQGRFQDNGSCGYVLKPDFLRDPNTTFNANALAPGPWWRRKRLSVRVISGQQ
LPKVNKSKNSIVDPKVTVEIHGVGRDVASRHTPVVTNNGFNPWWDKEFEFEVAVPELALV
RFVVEDYDASSKNDFIGQSTIPLNSLKQGFRHIHLLSKNGDQHPSATLFVKVSVQDC

NT seq 2334 nt +upstreamnt +downstreamnt
atgcagtgcctagggatccggcgccggagccgctctcaagagctctacctacaggagcag
agccgcaaggtggcagcgctcaatgggcagagattaggcctgcagggtgacgaggacctc
caggccctgttgaagggcagtcagctcctgaaggtgaagtccagctcgtggcggagagag
cgcttctacaagctgcaggaggactgcaagaccatctggcaggagtcccgcaaggtcatg
cggagtcctgagtcccagcttttctccattgaggacattcaggatgtgcgcatggggcac
cgcacggagggcctggagaagtttgcccgcgatgtgcctgatgaccgctgcttctccatc
gtcttcaaggaccagcgcaacacgctggacctcatcgcaccatcgcccgcagacgcccag
cactgggtacaggggctgcgtaagatcatccaccactcgggctccatggaccagcggcag
aagctacaacactggattcattcctgcttgcgaaaggctgacaagaacaaggacaacaag
atgagcttcaaggagctgcagaacttcttgaaagagctcaacatccaggtggatgacaac
tatgcacgcaagatcttcagggaatgcgaccactcccagaccgattccctagaggacgag
gagattgaggtcttctacaagatgctcacccagcgggctgagatcgaccgcatctttgcg
gaagccacaggctctggggagaccatgtctgtgggccagctggtgacgtttctgcagcac
cagcagcgggaggaggaggcggggccagccctggccctctccctcattgagcgttatgag
cccagtgagactgccaaggcggagcggcagatgaccaaggacggcttcctcatgtacctg
ctgtcggccgatggcagcgctttcagcctggcgcaccggcgggtctaccaggacatgaac
cagccgctcagccactacctggtgtcgtcctcacacaacacttacctgctggaagaccag
atcactgggcccagcagcaccgaagcctacatccgggcgctctgcaaaggttgccgctgc
gtggagctcgactgctgggatgggcccaacctggaacctgtcatctaccatggctacaca
ttcacctccaaaatcttcctctgcgacgtgctcagggccatccgggactatgcattcaag
gcctccccttatccggtcatcctgtccctggagaaccactgcagcctggagcagcagcgc
gtcatggctagccacctgcgcagcatcctgggccctctgctgttggaccaaccactcgag
ggcgtcaccagcagcctgccttcccccgagcaactgaaggggaagatcttgctgaagggg
aaaaagcttgggggtcttgtgccccctggaggggaggcaggtccagaggccaccgtttca
gatgaagatgaggctgcagagatggaggatgaagcagtgaggagtcgggtccagcacaag
cccaaggaggacaagctgaggctagcgaaggaactctccgatattgtaatttattgcaag
agcgtccactttgggggcttctccagccctggcagccctgagcaggccttctatgagatg
gtgtccttctccgagaatcgcgctgttcgcctgctccaggaatccgggaacagctttgtc
cgccacaacgtgaaccatctgagccgaatctaccccgctgggaggaggacagactcgtcc
aactaccacccagtggacatgtggaacgggggctgccagattgtggccctgaacttccag
actccgggaccagagatggacgtgtaccaggggcgcttccaggacaacgggtcctgtggg
tacgtgctgaaacctgacttcctgcgagaccccaacaccaccttcaacgcaaatgccctg
gctccagggccctggtggaggcggaagcggctcagtgttagggtcatctcagggcagcag
ctgcccaaggtcaacaagagcaagaactccattgtggaccccaaggtgacggtggagatc
catggtgtggggcgtgacgtggcgagccgccacacgcctgttgtcaccaataacggcttc
aacccatggtgggacaaggagtttgagtttgaagtggctgtccccgagctcgccctcgta
cgctttgtggtggaggattacgacgcctcatccaagaacgacttcattggccagagcacc
atccccctgaacagcctcaagcagggattccgccacattcacctcttgtccaagaacgga
gaccagcacccatctgctaccctctttgtgaaggtgtctgtgcaggattgctaa

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