Sorex fumeus (smoky shrew): 130039372
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Entry
130039372 CDS
T10594
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum00010
Glycolysis / Gluconeogenesis
sfum00020
Citrate cycle (TCA cycle)
sfum00620
Pyruvate metabolism
sfum00785
Lipoic acid metabolism
sfum01100
Metabolic pathways
sfum01200
Carbon metabolism
sfum01210
2-Oxocarboxylic acid metabolism
sfum04066
HIF-1 signaling pathway
sfum04922
Glucagon signaling pathway
sfum05230
Central carbon metabolism in cancer
sfum05415
Diabetic cardiomyopathy
Module
sfum_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
130039372 (PDHA1)
00020 Citrate cycle (TCA cycle)
130039372 (PDHA1)
00620 Pyruvate metabolism
130039372 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
130039372 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
130039372 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
130039372 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
130039372 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
130039372 (PDHA1)
Enzymes [BR:
sfum01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
130039372 (PDHA1)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
130039372
NCBI-ProteinID:
XP_055987229
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVFRVLAGASPKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPETTVLTREE
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAGINPTDHLITAYRA
HGFTLTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSEPPFEVRGANQWIKYKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtcttccgcgtgttggccggcgcctccccgaagcccgca
agcagagtgctggtggcatcccgaaattttgctaatgatgctacgtttgaaattaagaaa
tgtgaccttcaccgactggaggaaggtcctcctgaaacaacagtgctcaccagggaggaa
gggctcaagtactacaggatgatgcagactgtgcgcaggatggagttaaaggcagatcag
ctgtacaagcagaagattatccgtggcttctgtcacttgtacgatgggcaggaagcttgt
tgcgtgggcttggaggctggcataaaccccacagaccatctcatcacggcctatcgggct
cacggctttaccttaactcgtggtcttactgtcagagaaattcttgccgagcttacaggt
cgaagaggaggctgtgctaaaggaaaagggggctccatgcacatgtacgctaagaacttc
tacgggggcaatggcatcgttggagcccaggtgcccctgggagctgggattgcactggcc
tgtaagtataatggaaaagatgagatctgtttgactttatatggcgatggtgctgctaat
cagggtcagatttttgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgaaaataaccgctatggaatgggaacatctgtcgagagagcagcggccagcaca
gattactacaagagaggcgacttcatcccaggactgagggtagacggaatggatgtctta
tgtgtccgggaggcgacgaagtttgcagctgctcattgtagatctggaaaggggcccata
cttatggagctacagacgtaccgttaccacggacacagcatgagtgatcctggagtcagt
tatcggacacgagaagaaatccaggaagtaagaagcaagagtgatcctatcatgcttctc
aaggatagaatggtgaacaacaatcttgccagtgttgaagagttaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccactgctgatccagaaccgcct
ctggaagagctgggctatcacatctatagcagtgagccaccttttgaagttcgtggtgca
aatcaatggatcaagtataagtctattagttaa
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