Sorex fumeus (smoky shrew): 130040661
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Entry
130040661 CDS
T10594
Symbol
HTT
Name
(RefSeq) huntingtin isoform X1
KO
K04533
huntingtin
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum05016
Huntington disease
sfum05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
130040661 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
130040661 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
sfum03019
]
130040661 (HTT)
04131 Membrane trafficking [BR:
sfum04131
]
130040661 (HTT)
03029 Mitochondrial biogenesis [BR:
sfum03029
]
130040661 (HTT)
Messenger RNA biogenesis [BR:
sfum03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
130040661 (HTT)
Membrane trafficking [BR:
sfum04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
130040661 (HTT)
Mitochondrial biogenesis [BR:
sfum03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
130040661 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
HEAT_ECM29
Motif
Other DBs
NCBI-GeneID:
130040661
NCBI-ProteinID:
XP_055988634
LinkDB
All DBs
Position
Unknown
AA seq
3118 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQPPPPPSQLPQPPPQAQPPPPQPQPPPPPPPPPQPQGPA
GADEPLHRPKKELLATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSDDA
ESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRP
QKCRPYLVNLLPCLTHTSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIANL
RASSPTVRRTAAGAAVSICQHSRRTQYFYSWLLSVLLGLLVPVEDGHSTLLILGVLLTLR
YLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHQDHNVVTGALEL
LQQLLRTPPPELLLALTTAGGGGQLAGTKDEPGGRSRSGSIVELIAGGGSSCSPVLPRKQ
KGSMLLGEAAALEDDTEPRSEGSSPAFTASVKGEIGGELAASSGLSTPGSANSTADSAAH
DIITEQPRSQHTLQPDTVELSSCDLTSAATDGDEEDILSPSSSQISAVPSDPATDLNDGT
QASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGVDSQHSGIGQPEDEDISDEASDAFRSS
SLALQQAHLLERVGHSRQPSDGSVERLALREDAVEPSELENKPCRIKGDIGHSADDDSAP
LIHCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAVALHPEAFFSKLYRVPLD
PMEYPEEQYVSDILNYINHGDPQVRGATALLCGTLICSVLSSSRFHVGHWMGNIRALTGN
TFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCIMSLCSSSYSALGLQLLTDVLSLRNSS
YWLVRTELLETLAEIDFRLVSFLEAKADSLHRGAHHYTGLLKLQERVLTNVVIYLLGDED
PRVRHVAAASLARLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPPCHFSVSTI
TRIYRGYNLLPSITDVTMENNLSRVIAAVSRGLITSTTRALTFGCCEALCLLSTAFPVCI
WSLGWHCGVPPLSATDESRKSCTVGMAAMVLTLLSSAWFPLDLSAHQDALILTGNLLAAS
APKSLRSSWNSEEEATPAATKQEEVWPALGDRSLVPMVEQLFSHLLKVINICAHVLDDVT
PGPALKAALPSLTNPPSLSPIRRKGKEKEPGEQASAPLSPKKGSEASPASRQSDTSGPVT
ANKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSSEKFGGFLRSALDVLAQILEL
ATLQDIGKCVEEILGYLKSCFSREPTMATVCVQQLLKTLFGTNLASQFDGLSSNPSKCQG
QAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQDHDPAGWFDVLQKVSTQ
LKSNLTSVAKNRTDKNAIHSHIRLFEPLVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRV
NYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPKI
IQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQ
YHQVVEMFILVLQQCHKENEDKWKRLSRQVADVVLPMLARQQMHIDSHEALGVVNTLFEI
LAPASLRPVDMLLRSMFVTPNTMASVSTVQLWISGILAILRVLISQSTEDIVLSRIQELA
LSPYFISCQIINRLRDGDRSPTPEEHSEGKQTKMLPEETFSRFLLQLVGILLEDIGTKRL
RVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAATRLFTAEATDGSFYGLESLKA
RVRSMAPTHPALVLLWCQVLLLVSHTDYRWWAEVQQTPKRRSLSSTKTLSPQLSGDEEDS
DSAARLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLSHEPPVQDFI
SAVHRNSAASGLFIQAIQSRCDNLSAPATLKKTLQCLEGIHLSQSGAVLTLYVDKLLSTP
LRVLARMVDTLACRRVEMLLAANLQSSAAQLPAEELRRIQEHLQSSGLAQRHQRLYSLLD
RLRLTSAPGSRGPTPPLMSHPLDGDGPLALETINPDKDWYIHLVQSQCWTRSDSALLEGA
ELVNHIPAGDMNAFMMDPEFNLSLLAPCLGLGLREISGGQKSPLFEAARMVTLDRVASMV
QQLPAVHQVFQPFLPAEPTAYWNKLDDLFGDAALYCSLTTLARALAQYLLATSKLPSRLH
LPPEKEGDTVKFVVMVLEALAWQLVHEHIPLSLDLQAGLDCCCLALQLPGLWSLVSSPDM
VTHACSLIHCVRCLLEAIVVQPGDQLLSPERTDIPQTARNEVGSNAQTPEYVATACVMVA
EMVESLPSVLALGHQRSSGVPAFLTPVLRNIVVSLARLPLVNSYTRVPPLVWKLGWSPRP
GGDFGTVYPEIPVEFLQEKEVLKGFIYRINTLGWTSRTQFEETWATLLGVLVTQPLVLEQ
EESPPEEDTERTQINVLAVQAISSLVLSAMTVPVAGNPAMSCLEQQPRSKPLKALDTRFG
RKLSIIRGIIEQEIQAMVSKRENIATHHLYQTWDPVPSLSAATTGALISHDKLLLQTNPE
RELGDMSYQLGQVSIHSMWLGNNITPLRAEEWGDDEEEEADTPAPVSPPTSPVNSRKHRA
GVDIHSCSQFLLELYSRWILPSSSARKTPVILISEVVRSLLVVSDLFTERSQFEMMYVTL
MELRRAHPAEDEILLQYLVPATCKAAAVLGMDKAVAEPVSRLLESALRSSHLPSKIGALH
GVLYVLECDLLDDTAKQLIPVVSDYVLSNLKAVAHCVNVHSQQHVLVTCATAFYLIENYP
LDVGPEFSASIIQMCGVMLSASEEATPSIVYHCVLRGLERLLLSEQLSRLDSESLVKLSV
DRINVHSPHRALAALGLMLTCMYTGKEKISPGRAPEPSPASPDSESVIVAMERVSVLFDR
IRKGFPCEARVAARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQTLH
NTGQSSMVRDWVMLSLSNFTQRTPVAMAVWSLSCFFISASTSPWVSAILPHVVSRMGKLE
QVDINLFCLVATDFYRQQIEEELDRRAFQSVFEVVAAPGNPYQRLLTCLRNLHEGAAC
NT seq
9357 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctggaaaagctgatgaaggccttcgagtccctcaagtcgttccagcagcag
cagcagccgccgccgccgccgtctcagctgcctcagccgccgccgcaggcgcagccgccg
ccgcctcagccgcagccgccgccgccgccgccgccgccgccgcagccgcagggcccggcc
ggggccgacgagccgctgcaccgaccaaagaaagaactcttggccaccaagaaagaccgt
gtgaatcactgtctgacaatctgtgaaaacatagtagcgcagtctctcagaaattctcca
gaattccagaaactcctgggcatcgccatggagcttttcctgctgtgcagtgatgacgcc
gagtctgatgtgaggatggtggctgacgagtgtctcaacaaggtcatcaaggccctgatg
gactccaacctcccacggctgcagctcgaactctacaaggaaataaagaagaacggtgca
tctcgaagcctgcgtgcggccctgtggaggtttgctgagctggcacacctggtccggccc
cagaaatgcaggccgtacctggtcaacctcttgccttgtctgactcacacaagcaagagg
cccgaggaatctgttcaggaaaccttggctgccgccatacccaagatcatggcttccttt
ggcaattttgcgaacgacaatgaaattaaggttttgttgaaagctttcatcgcgaacctt
cgcgccagctccccgactgtccggcgcaccgcagctggcgccgccgtgagcatctgccag
cactcccggaggacacagtatttctacagctggctgctcagcgtgctcctgggcttactt
gttcctgtcgaggacggacattccacactcctcattcttggggtgctgctcacactgagg
tatttggtgcccctgctgcaacagcaggtcaaggacaccagcctgaaaggcagctttggg
gtgacacggaaggaaatggaggtctcgccctcgacagagcagcttgtccaggtgtacgag
ttgaccctgcactacactcagcaccaggaccacaacgttgtcaccggggcgctagagctc
ctgcagcagctcctgcgcaccccccctccagagctgctgctggccctgaccacagccggt
ggtggggggcagctggcgggtaccaaagatgagccaggtggccggagtcggagtgggagt
atcgtggagctgatcgctggaggggggtcttcctgcagccccgtgcttcccagaaagcaa
aaagggtcgatgctgttgggagaagcagctgccttggaggatgacacggagccaaggtca
gagggcagcagcccagccttcacagcctcggtcaagggtgagatcggtggtgagctggca
gcctcttctggcctctccacgccgggctcggccaactcgaccgcggactcggcggcacac
gacatcatcaccgagcagccccgatcacagcacacactgcagcccgacacagtggaactg
agcagctgcgacctaaccagcgcggccaccgacggggatgaggaggacatcctgagcccc
agctccagccagatcagtgccgtgccgtctgaccccgccacggacctgaacgatggcacg
caggcctcctcacccatcagcgacagctcccagacaaccaccgaggggcctgattcagct
gtgaccccttcagacagttccgaaattgtcttagatggtgtggacagtcagcactcgggg
atcggccagcccgaggatgaggacatttccgacgaggcttcagacgccttcagaagctcc
tccctcgccctgcagcaggcgcacttgctggagcgcgtgggccacagcagacagccgtcc
gatggcagcgtggagcgccttgcactgagagaggatgctgtggagcccagcgagcttgag
aacaagccctgccggatcaaaggtgacataggacactctgcggatgatgactctgctcct
cttatccactgtgttcgccttttgtctgcatcatttttgctgacaggggagaagaacgtc
ctggttcctgacagggacgtacgggtcagcgtgaaagctctggcgctcagctgcgtggga
gcagccgtagccctgcacccggaagctttcttcagcaaactttacagagttcctttggac
cccatggaatatcctgaggagcagtacgtgtctgacatcctgaactacatcaaccacgga
gacccacaggtccgaggagccacagccctcctctgcgggaccctcatctgctccgtcctc
agcagttcccgcttccacgtgggacattggatgggcaacatccgagctctgacaggaaac
actttttctctggtggactgcattcctttgctgcagaaaacgctgaaggatgaatcttct
gtaacctgcaagttggcttgtacagctgtacggcactgcatcatgagtctgtgcagcagc
agctacagtgcactggggctgcagttgctcaccgatgtgctaagcctgaggaacagctcc
tactggctggtgcggacggagctcctggagaccctggcagagatagacttccggttggtg
agctttctggaggccaaagcagacagcttacaccgcggagcacatcattacaccgggctt
ttaaaacttcaggaacgagtgctcactaatgttgtcatctatttgctcggggacgaagac
cccagggtccggcatgttgctgcagcttcgttagcgaggcttgtcccaaagctgttttat
aagtgtgaccaaggacaagctgaccccgtggtggccgtggcccgggaccagagcagcgtt
tacctgaagctgctcatgcatgagacgcagccaccctgccacttctccgtcagcaccatc
accagaatatatagaggctataacttactgcccagcatcactgatgtcaccatggaaaac
aacctttcgcgagtgatcgctgctgtgtctcgtggactgatcacctccaccactcgcgct
ctcacatttggatgctgtgaagctttgtgtctcctttcaacggcctttcctgtttgtatt
tggagcttgggctggcactgtggagtacccccgctgagtgccactgatgagtcccgcaag
agctgcacggtggggatggccgccatggtgctcaccttgctctcgtccgcctggttcccg
cttgacctgtccgcccaccaggatgccctcattttgacaggcaacttgcttgcagccagt
gcccccaagtctctcagaagttcttggaactctgaagaagaggccaccccagcagccacc
aagcaggaggaggtgtggcccgcgctgggggaccggagcctggtgccgatggtggagcag
ctcttctcccatctgctgaaggtcatcaacatctgtgcacacgtcctggatgacgtgact
cctgggcctgctctcaaggcagccttgccgtccctgacaaacccgccctcgctgagtccg
atccggcggaaggggaaggagaaagagcccggggagcaggcctcggcgccactgagccct
aagaaaggcagtgaggccagtccagcctctcgacagtctgatacttcagggccagtgaca
gccaacaaatcctcctctctgggaagtttctaccaccttccttcctacctcaaactgcac
gatgtcctcaaggccactcacgccaactacaaggtcaccttggatctgcagaacagctct
gagaagtttgggggctttctgcgctctgccctggatgttctcgctcagatcctcgagttg
gcaactctgcaggacattgggaagtgtgtcgaagagatcctggggtatctgaaatcctgc
ttcagtcgagagcccaccatggcgactgtctgtgtccagcaactgttaaagactcttttt
ggaacgaacttggcctcccagtttgatggcttgtcctccaaccccagcaagtgtcaaggc
caagcccagcgtctgggctcctccagcgtgaggccgggcttgtaccactactgcttcatg
gctccctacacccacttcacccaggccttggccgacgcaagcctgaggaacatggtgcag
gccgagcaggaccacgaccccgcaggctggtttgatgtactccagaaagtgtctacccag
ttaaagagtaacctcacgagtgtcgcgaagaaccgcacagataagaatgctattcacagc
cacatccgcctgttcgagccgcttgtcatcaaagctctgaagcagtataccaccaccaca
tccgtgcagctgcagaggcaggttttggatctgctggcacagctggttcagttgagggtc
aattactgtctcctggactctgatcaggtgtttatcggatttgtgctgaagcagtttgaa
tacatcgaagtaggccagttcagggaatcagaggcaattattccgaacatatttttcttc
ctggtgttactgtcttacgaacgctatcattccaagcagatcattggaattcccaaaatc
attcagctctgtgatggcatcatggccagtgggaggaaggccgtgactcacgccatccca
gccctgcagcccatcgtccacgacctgtttgtgttgagaggaaccaataaggccgatgcg
gggaaagagctggaaacgcagaaggaggtggtggtgtccatgctgctgagacttatccag
taccaccaggtggtggagatgttcatccttgtcctgcagcagtgccacaaggagaatgag
gacaagtggaaacgcctgtctcggcaggttgccgacgtcgtcctccctatgctggccagg
caacagatgcacatcgactcccacgaagccctgggcgtggtgaacacgctcttcgagatc
ctggcccctgcctccctccggcccgtggacatgctcctgcgcagcatgttcgtcaccccc
aacaccatggcctccgtgagcacggtccagctgtggatctccggtatcctggccattctg
agggtcctcatctcccagtcaacagaagacattgttctttctcggatccaggagcttgct
ctatctccctacttcatctcctgccaaataatcaataggttacgagatggtgacagaagc
ccgacaccggaagagcacagcgaagggaaacagactaagatgctgccagaagaaacgttt
tctcggttcctgctgcagttggtcggcatcctcctggaggacatcggcacgaagcggctg
agagtggaaatgagcgaacagcagcacacgttctactgccaggagctgggcacactgctc
atgtgtctcatccacatcttcaagtcaggaatgttccggaggatcacggctgccgccaca
cgcctcttcacagccgaggccactgatggcagcttctatggactggagagcctgaaggcg
cgtgtgcgctccatggcgcccacacacccagcgctggtgctgctgtggtgccaggtgctg
ctgctcgtcagccacacggactaccgctggtgggcggaggtgcagcagacccccaaaagg
cgcagtctgtccagcacgaagacactcagtccgcagctgtccggagacgaggaggattct
gactctgcagccaggctgggcatgtgcaaccgggagattgtgcggagaggcgcgcttatc
ctcttctgtgattatgtctgtcagaacctgcatgactctgagcacttgacgtggctcatc
gtgaaccacatccaggacctgatcagcctgtcccacgagccgcccgtgcaggacttcatc
agcgccgtccatcgcaactctgccgccagtggcctcttcatccaggccatccagtctcgc
tgtgacaacctgtcagctcccgccaccctgaagaagacgctgcagtgcctagaggggatc
cacctgagccagtcgggtgccgtgctcacgctctacgtggacaagctgctgagcaccccg
ctccgcgtgctggctcgcatggtcgacaccttggcttgtcgccgggtcgaaatgctcctg
gctgccaatttacagagcagcgcagcccagctgccagcagaggagctgcgccgcatccag
gagcaccttcagagcagcgggctggctcagagacaccagcggctctactccctgctggac
aggctccgcctcacctccgcccccggctcccgtggccccacgcctccgctcatgtcccac
ccgctggacggggatgggcccctggcactggaaacaataaatccagacaaggattggtac
atccatctggttcaatcccagtgctggaccaggtccgattctgccctgctggaaggggca
gagctggtgaatcacatccctgctggggacatgaatgcgttcatgatggacccggagttc
aacctcagcctgctcgccccctgcctaggcctgggcctgcgtgaaatttctgggggccag
aagagccccctgtttgaagcagctcgaatggtgactctggaccgtgtggccagcatggtt
cagcagcttcctgctgtccaccaagttttccagccattcctgcctgcggagcccactgct
tactggaacaaattagacgacctgtttggggatgccgcgctctactgttccctgaccact
ctggcacgcgcactggctcagtacctgctggccacttccaagctgcctagccgtttgcac
cttcccccagagaaggagggtgacaccgtgaagtttgtggtgatggtgctggaggcactg
gcctggcagttggtgcacgagcacatcccgctgagcctggacttgcaggctggcctggac
tgctgctgcctggccctgcagctgcctggcctatggagtttggtctcctctccggacatg
gtcacccacgcctgttccctcatccactgcgtccgctgcctcctggaagccattgtggtt
cagcctggagatcagctgctgagtcccgagaggactgacattccacagactgccagaaac
gaagtcggttcaaatgcgcagacccctgagtacgtggccacggcctgtgtgatggtggca
gaaatggtggagtccctgccgtcggtgctagccctgggccatcagaggagcagtggtgtg
ccggccttcctcacacccgtgctcaggaacatcgtggtcagcctggcgcgcttgcccctc
gtcaacagctacacacgtgtgcccccactggtgtggaagctcggctggtcaccgagacca
ggcggggactttggcacagtgtaccctgagatccctgtggaattcctgcaggagaaggaa
gtcctcaagggcttcatctaccgcatcaacacactagggtggaccagccggacacagttc
gaggagacgtgggccacccttcttggagtgctggtgacgcagccactcgtgctggagcag
gaggaaagcccaccggaagaggacacagagaggacccagatcaatgtcctggctgtgcag
gccatcagctccctggtgctgagcgccatgactgtacccgtggccggcaaccctgccatg
agctgcttggagcagcagccgcggagcaagcccctcaaagccctggacaccaggtttggg
agaaagctgagcatcatccgaggaatcatagagcaagaaattcaggcaatggtttcaaag
agagagaacatcgccacccatcacctgtaccagacgtgggatcctgtaccttccctgtct
gcagccactacaggtgccctcatcagccacgacaagctgctgctgcagaccaatcctgag
cgggagctgggcgacatgagctaccagctgggccaggtgtccatccattccatgtggctg
gggaacaacatcacgcccctgcgagcggaggagtggggtgacgacgaggaggaggaggca
gacacgcccgcaccagtctcgccgcccacatccccagtgaattccaggaagcaccgggct
ggagtggatatccactcctgttcacagttcctgctggagttgtacagtcgctggatcctg
ccctccagttcagccagaaagacgcctgtcatcctcatcagcgaagtggtgcgatccctc
cttgtggtgtcggacttgttcacggagcgcagccagtttgagatgatgtatgtgaccctg
atggaactgcggagagcacaccccgctgaggatgagatcctgcttcaatacctggtgccc
gccacctgcaaggcggctgctgtccttggcatggacaaggctgtggccgagcctgtgagc
cggctgctggagagcgcgctgcggagcagccacctgcccagcaagattggggccctgcat
ggcgtcctctacgtgctggagtgtgacctgctggacgacactgccaagcagctcatcccg
gttgtcagcgactacgttctctccaatctcaaggccgtggcccactgcgtgaacgtccac
agccagcagcacgtgctggtgacctgtgccaccgccttctacctgatcgagaactaccct
ctggatgtggggcccgagttctcagcatccatcatacagatgtgtggggtgatgctgtcg
gccagtgaggaggccaccccgtccatcgtctaccactgcgtgctgcggggcctggagcgc
ctcctgctgtccgagcagctctcccggctggactctgagtccctggtgaagctgagcgtg
gacagaatcaacgtgcacagcccacaccgcgccctggcggccctgggcctgatgctcacc
tgcatgtacacaggaaaggagaagataagccccggcagggcccctgagcccagcccagct
tccccggacagcgagtcagtgatcgtggccatggagcgtgtttccgtgctcttcgacagg
atccggaagggctttccctgtgaggcccgtgtggcagcgcggatcctgccccagtttctc
gacgacttcttcccaccccaggacgtgatgaataaagtcatcggggagtttctgtccaac
cagcagccgtacccacagttcatggccactgttgtgtacaaggtcttccagacgctgcac
aacacaggccagtcatccatggtgcgggactgggtcatgctgtcgctgtccaatttcacg
cagaggaccccagtggccatggctgtgtggagtctctcctgcttcttcatcagcgcctcg
accagcccgtgggtgtcagccatcctcccgcatgtggtcagcaggatgggcaagctggag
caagtggacattaacctcttctgcctggtggccacggacttctacaggcagcagatagag
gaggaactggaccgccgggcctttcagtcggtgtttgaggtggtggcggcacccgggaac
ccgtaccagcgcctgctcacgtgcttgcggaacctgcacgagggcgccgcgtgctaa
DBGET
integrated database retrieval system
