Sorex fumeus (smoky shrew): 130040668 Help Entry 130040668         CDS       T10594                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum05014   Amyotrophic lateral sclerosis Brite Enzymes [BR:sfum01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      130040668 (SETX)     5.6.2.5  RNA 5'-3' helicase      130040668 (SETX) Transcription machinery [BR:sfum03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      130040668 (SETX) BRITE hierarchy SSDB OrthologParalogGFIT Other DBs NCBI-GeneID:  130040668 NCBI-ProteinID:  XP_055988641 LinkDB All DBs Position Unknown AA seq 2544 aa AA seqDB search MSTCCWCTPGGTSTVDFLKRYAAQPALCSEFQTANEDLCYCLECVVEYHKARDELPLFHE VLWELEIVRLTNHFEKSMSAEIGDDDDDELYIVDINGEAQLFDFTGQDFENKLRVPLLEI LKFPYLLLHERVNELCVEALCRMEQANCSFQVFEKHPGIYLFLVHPNEMVRRWAILTARN LGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDVANYKNY WLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERPAQDDSMDPFWPALHCFMVIL DRLGSKVWGQLIDPIEAFQTIINNVSYNREIQTIRKSSARPKFEPEPYMADMVTCSQIVY NFNPEKTKKDSGWRSAICPDYCPNMYEEMETLTSVLQSDIGQDMRVHNSTFLWFIPFVQS LMDLKDLGVAYILEVIHHLHSEVKDVLNQANTVCDKVTEFFLLILVSVVELHRNKRCLHL LWVSSQQWVEAVVKCAKLPTSAFARSIEKSATSGSKGSPVVSTLSLHMAQGNSVQLACVQ LIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTAQETQELQMCLKQIIRNIKA KGPQGGMLAELPPPSKSPRRSEETEKLRKDVPPPESSSPAPPKEPGRVGGGPVHEGALGR APKTVEKHEPGASRLQGPLPVAPAFKQSGESRYPDGAPEPGQGSAQGQRALSNDPAITPK NRASSRGLEGEPDRGFDTAAHGENSSLRDGTLGKNVRVKSKAQKDEFCAKLSHVIKQQHR KSTLVHSGVNLEETLTVSSIESFYSRRGAGDARGDGGFLHNLCVGPRSVLGERSKDLTCS DTSVLEKKQVLNDELETCSHEHSHQARKRENEKDLVSLIEVTSSFLRKTSPSEEPVTTLD SQEVAGKLGRGALADFQDRPLSPRPDTLTDSQIDQDLYDLSLLAQASASKFPSESSQKSP CQLQRKVREDKRCFTAKATSTRDVSSDHVIIISDSDDEEDSTLSAKKRVKVDPGVPEEEE EEEQAVSTADSSVDNEALKEEQTKLLEFEESDSQFFEFETPCEVFSVWQDQKQDKHSDQE DEESSSVPCGVGAAQEQGRAGNTVPGGAATDGPVGAREPAGPGISVEICEMEAKKPKRKH FEKPSAEKPQKAPAPARSGEQPDDPPVAGQVAKAVKSARAAPTASVVPRASKKAPPGART YSAPVRRSPVAKGTKKAHSEPRKGPAKTHYLKCRATPAVIPPKKFRQFPEPASKAERLGL KKAPRKAFDLSQRSRDSISELRDYGKVAGAVDIQKKTKLIAPQMLSVRNNKKLLTMQEPH FVRRAMWSRLGVGKGGQRPEHWAEARRPEPAPADRRPGPDAFAEGLGKPFLKTDPGRARA GSDVMDGGVRLADSAVAATAEPERHVGVAADPQPEPDSDSDSELESLFLTQHDPQDMDLC SQMESDHSTAVQGTALATGRAESPQGPRFEHKDSAETARGQGTPKAAATVFLKPTMPPPG PKPRPTNTKVFSSSHTSRLANFSRSLESSSAAPRPAKSKASGVLPVPKAGPPPPPPKAAP PPPPPPPKPAPAPVPPTLKTPPETKGPWSSVFSAPTASSRSVFRPPFAENRSLSTVYPAS VHLSPQAIADAFVKEVLKWKLDMFLNFNQCGPPASLCQAITRPVPVRFQDSGEYFNVFFP LVILNTFETVAQDWSSSSNKSYSLLFRKFPANQKYWEFVVHLDESELAKQLHPKENDLVF LVPERRDRDRKDTERKYVPEAQEHFCGFVQKFRRTSAMRSGKSECCLSIQTQDQLPLHVN ESVRCLVISSLVTTQRKLKAMSLLSGRNQLARVVLNPNPMDFCTKDLLTTSSERITSYLR DFNEDQKKAIETAYAMVKQSPAVAKICLIHGPPGTGKSKTIVGLLYRLLTETQKRGHSDE NSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSI NTEVLKFSLDSLVSHRMKRDLPSHVQDMHRQKQSLDHQLDELSRQRALCRGAREKQRQEL DDKIAKVSKERQELASKIKEVQGRPQKTQSLIILESHVICCTLSTSGGLLLEAAFRGQGG VPFSCVIVDEAGQACEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMAR FYKLLEEKVKQSLIGRMPIVQLTVQYRMHPDICLFPSSYVYNRSLKTNRTTEMLRCSSDW PFQPYLVFDVGDGAERRDNDSYVNVQEIKLVMEIIRLIKEKRKDVTFRNIGVITHYRAQK ILIQRDLDREFDRKGLAEVDTVDAFQGRQKDCIIVTCVRANSVQGSIGFLSSLQRLNVTI TRAKYSLFILGHLRTLMDNEHWNQLIQDAQKRGAIVKTCSRSYRHDAMKILKLKAGPLHR SLTHPPAGAPEAARPPGGLPSSTLDGGLTTSSPYLTPPDSGESPVPVKDPEKPPVQDRLR DPRLLRRLGVSLGPQPPRVCPVLGEPGTLGGMQDLSGLLLSAHCPLDTLPPGEPRAASVP QRTAGWDKGPLGDGDSYPKRRKLL NT seq 7635 nt NT seq  +upstreamnt  +downstreamnt atgagcacttgctgctggtgtaccccgggcgggacctccactgtcgacttcctgaagcgc tatgcagcccagccagccctgtgcagcgagttccagacggccaacgaggacctctgctac tgcctggagtgcgtggtcgagtatcacaaggcgagggacgagctgccactcttccacgag gttttatgggaattggaaattgtacggctcacaaaccattttgaaaaatccatgagtgcg gaaatcggtgatgacgatgacgacgagttgtacattgtggacatcaatggagaggcgcag ctgtttgacttcaccggccaagactttgagaacaagctccgagtgccacttctggaaatc ctgaaattcccgtatctgctcttacatgaacgtgtcaatgagctgtgtgtggaggcgctg tgtcggatggagcaagccaactgctccttccaggtgttcgagaagcaccccgggatctat ctgtttctggttcaccccaacgaaatggttaggcgttgggccatcctgactgccaggaac ttggggaaagtggacagagatgattattacgacttgcaggaggttctgacgtgcctgttt aaagtgattgagctggggctgctggagagcccagacatctacacttcctctgttctcgag aagggcaagctgatcctcctgcccgcgcacatgtacgatgtcgccaactacaagaactat tggttagggatctgcatgctgctgaccatcctggaggagcaggccatggactcgctgctg ctcggctccgacaagcagaacgacttcatgcagtccatcctgcataccatggagcggccc gcccaagatgatagcatggatcctttctggccggccttacattgtttcatggtgatcctg gaccgtctgggatcgaaggtctggggccagctcattgatccgatcgaggcgtttcaaacc atcatcaacaacgtgagctacaacagagagatccagactattcggaagagctctgcgagg cccaagttcgagccggagccgtacatggctgacatggtgacttgcagccagatcgtgtac aacttcaaccctgagaagaccaagaaggactcaggttggcgctcggccatctgcccggat tactgccccaacatgtatgaggagatggagacgctgaccagcgtgctgcagtcggacatc gggcaggacatgcgcgtgcacaacagcaccttcctgtggttcatccccttcgtccagtcg ctcatggacctcaaggacctgggcgtggcctacatcctggaggtcatccaccacctgcac tcggaggtcaaggacgtcctcaaccaggccaacactgtgtgtgacaaggtcaccgagttc ttcctgctcatcctggtgtccgtggtcgagctgcacaggaacaagaggtgcctgcacctg ctgtgggtgagctcccagcagtgggtcgaggccgtggtcaagtgcgccaagctcccgacc agcgccttcgcgcgcagcattgagaagtcggccaccagcggctccaagggctccccggtc gtctccacgctgtccctgcacatggcgcagggcaactcggtgcagctggcctgcgtgcag ctcatcaggagtctgctcaaggaaggctaccagctgggccagcagaccctgtgtaagcga ttctgggacaagctcaacttgttcctgagaggcaatctgtccctgggctggcagctgacc gcgcaggaaacccaggagctgcagatgtgtttgaagcagatcattaggaacatcaaggcc aagggcccgcagggtggcatgcttgcagagctgccgcctccatccaaaagccctcggaga agtgaagaaaccgagaagcttcggaaagacgtgccccctccggaaagttccagccctgct ccccctaaggagcccgggagagtgggtggaggccccgtgcacgaaggggcgctggggaga gcaccgaaaaccgtcgagaagcatgagccgggggcctccaggctgcaggggcccctcccg gtcgcgcccgctttcaagcagagtggcgagagccgttatcccgatggtgctcccgagccg ggccaaggcagcgcccaggggcagagggctctcagcaacgatcccgccatcacgcccaag aaccgtgcgtcaagcagaggcctcgaaggggaaccggacaggggattcgacacagccgca cacggcgagaactcctctctcagggacggtactctcggcaaaaacgtaagagttaaaagc aaggcacagaaagatgaattttgcgccaagttgtcacatgtgataaaacagcaacaccgg aaaagtactctggtccacagtggggtgaatctagaggaaaccctgaccgtgtccagcatc gagagcttctactcgaggagaggtgccggagacgcgcgaggggacggaggcttcttgcac aatctctgtgtcggcccgcgcagtgttctgggcgagaggagcaaggacctgacctgttcc gacacttcagtgctggaaaagaagcaggtgctgaacgacgagctcgagacttgctcccac gaacacagccaccaggcccggaaacgtgagaatgagaaagatctggtctcgctcatagaa gtgaccagcagtttcctaagaaagacctcgccctctgaggagccagtgaccacactggac tcccaagaggtggccggcaagctgggcagaggggctctcgcggacttccaggatcggccc ctcagccccaggcccgacaccctgacggactcgcagatcgaccaggatctctatgactta tccttactggcgcaggccagcgcgagcaagttcccgtccgagtcctctcagaagagcccc tgccagcttcagaggaaggtccgggaggacaaaagatgcttcacggccaaggcgaccagc acccgggacgtcagctccgaccacgttattattatttctgattccgatgacgaggaggac agtactctgagtgcgaagaagcgcgtgaaggtggatcccggggtcccggaggaggaggag gaggaggagcaggcggtttccacggcagactcaagcgtggacaatgaggccctgaaggag gagcagaccaagctgcttgagttcgaggagtcggactctcagtttttcgagtttgagacc ccttgtgaagtgttttcagtttggcaggatcagaaacaagacaagcattcagatcaagag gatgaggaaagttcctctgtgccgtgtggcgtgggagccgcccaggagcagggccgggcc ggcaacaccgtgccggggggggcagccacggacgggcccgtgggtgcccgggaaccggca gggccaggcatttctgttgagatctgtgaaatggaagcgaagaaaccgaagaggaaacac tttgaaaagcccagtgctgagaagccccagaaggcgcctgcccctgcccgaagtggggag cagcctgacgacccccccgtggcagggcaggtggcaaaggccgtgaaaagcgccagggcc gcccccaccgcttccgtcgttcccagggcctcaaagaaggcgcctcccggtgcccgcacc tactctgcgcccgtccgacggagccccgtggccaagggcaccaagaaggcccactcggag ccccggaaggggccggcgaagacccattacctcaagtgtcgggccactcctgctgtcatc ccgcccaagaagttccgccagtttcccgagcctgcctcgaaggcggagcgactggggctg aagaaggcgcctcgcaaggccttcgacctgtcccagaggtcgcgcgacagcatctcggag ctccgggactacggcaaggtggccggggcagtcgatatccagaaaaagaccaaattaatc gcgccccagatgctctcagtcagaaataacaagaagctgctgaccatgcaggagccacac tttgtgcgcagggcgatgtggagcaggctgggcgtcgggaaagggggacagcgccccgag cactgggccgaggcccggcgcccagagccggcacccgctgaccgcagaccaggccccgat gccttcgccgagggcctggggaagcccttcctcaagacggaccccgggagggccagagcc ggctctgacgtgatggacggaggtgtcaggctggcagactcggcggtggcggccactgcg gagcctgagcgacacgtgggggtggctgccgacccacagcccgagccggactccgacagc gactctgagcttgagagcttgttcctcacccagcacgacccacaggacatggacttgtgt tcccagatggagagtgaccacagcaccgccgtgcaggggacggctttggccacggggcgg gcagagtccccgcagggccccaggttcgagcacaaggacagtgcagagaccgcgaggggc cagggcacacccaaggccgccgccactgtgttcctcaagcccaccatgccgccccccggg cccaagcccaggcccaccaacaccaaggtcttcagctccagccacacctcgcgcctggcg aacttctccaggtctctggagagcagctctgctgccccgcggccagccaagagcaaggcc agtggggtgctgcctgtgcccaaggccggccctccgccccctccgccgaaggccgcccca cctccgcccccgcccccacccaagcctgccccagcccctgtgccgcccaccctgaagacc ccgcccgagaccaagggcccctggagcagcgtcttctcagcgcccactgcgtcctccagg tctgtgttcaggcctccctttgccgagaacaggtccctgtccacggtctacccggccagc gtccatctgtccccgcaggccatcgccgatgccttcgtcaaagaggtcttaaagtggaag ctcgacatgttcctgaacttcaaccagtgtgggccgcccgccagcctgtgccaggccatt accaggcccgtgcccgtgcgcttccaggactcaggggagtatttcaacgttttcttcccg ctggtgatactgaatacttttgaaacggtggcacaggattggagcagctcttcaaataag tcctactcattgctgtttcgaaaattccctgctaatcagaaatattgggagtttgtggtt catctggacgaaagcgaattggccaaacagcttcatcccaaggaaaatgatttggtgttc ttggttcctgagagacgagaccgagacaggaaggacaccgagcggaagtacgtgccggag gctcaggagcacttctgcggctttgttcagaaattccgccgcacctcagccatgcgcagc ggcaagtccgagtgctgcctgtccatccagacgcaggaccagctgcccctgcacgtcaac gagtccgtgcgctgcctcgtcatcagctccctggtaaccacacagaggaagctgaaggcc atgtctctcctgagtggtcggaaccagctggccagagtcgtgctcaatcccaaccccatg gacttctgcaccaaggacttgctgacgacgagctcagagagaatcacctcctacctgcga gatttcaacgaagaccagaagaaagccatcgagacggcctatgccatggtgaagcagtcg ccggccgtcgccaagatctgtctcatccacgggcctcccgggacaggaaaatccaagacg atcgtcggcctcttgtaccgcctcctgacagagacccagaagaggggccactcggatgaa aactccaatgccaaaatcaaacagaaccgggtcctggtgtgtgcgccctccaatgctgcc gtggacgaactcatgaagaaaatcatcctcgaattcaaagaaaaatgtaaagacaagaag aaccctttgggaaactgtggagatatcaatttagtacgtctgggtccagagaagtcaatt aatactgaggtcctaaaattcagcctggacagcctagtcagccacagaatgaaaagagat ttgccttctcacgttcaggacatgcataggcagaagcagagcctggatcaccagctggac gagctttcccgccagcgagctctgtgccgaggggcgagggagaagcagagacaagagtta gatgataaaattgccaaggtttcgaaagaaaggcaggaactggcatctaaaatcaaagag gtccagggacggccccagaagacacagagcctcatcatcctggagtcgcacgtcatctgc tgcacactgagcacgagcggggggctgctgctggaggcggccttccgcggccagggcggc gtgcccttcagctgcgtcatcgtggacgaggccgggcaggcgtgtgaggtggagaccctg acgcccctcatccatcgctgcaacaagctcatcctggttggagaccccaagcagctcccc ccaaccgttatctccatgaaggcccaggagtacggctacgaccagtcgatgatggcccgt ttctacaagctactggaggagaaggtgaagcagagcctgatcggccggatgcccatcgtg cagctgactgtgcagtaccgcatgcaccccgacatctgcctcttcccctccagctacgtc tacaacaggagcctgaagaccaacaggacgaccgagatgttgcgttgctcatcagactgg cccttccagccctacctggtgtttgatgtgggcgacggcgcagagcggcgggataatgac tcatatgtgaacgtccaagaaatcaaactggtcatggaaataatcagacttatcaaggag aagcggaaggacgtgaccttccggaacatcggcgtcatcacccactaccgggcgcagaag atcctgattcagagggacctggacagggagtttgaccggaaaggactggcagaagtggac acggtggacgcgttccagggccgccagaaggactgcatcatcgtgacgtgtgtccgagcg aattccgtgcagggctccattggcttcctgtccagtctgcagcgactgaatgtcaccatc acccgggccaagtacagcctctttatcctcgggcatctgcgtaccctgatggacaacgag cactggaaccaactgatccaggatgcgcagaagcgcggcgccatcgtgaagacatgcagc cgcagctaccggcacgacgcgatgaagatcctgaagctgaaggccggcccgctgcatcgc agcctgacgcacccgcccgctggcgcccccgaggccgcccggcccccagggggcctcccc agcagcacactggatggcggcctcaccacctcgtccccctacctcacgccccccgactcc ggtgagtccccggtccccgtcaaggaccccgagaagcccccggtgcaggaccgcctccgg gacccccggctgctgagaagactgggtgtctccctgggtccccagcccccccgcgtctgc cccgtgctgggggagcctggaaccctcgggggcatgcaggatctgagcggcctgctgctg tctgcacactgccccctggacacgctgccccccggggagccacgggctgccagcgtcccg cagaggaccgcaggctgggacaaggggccactgggtgacggcgacagctaccccaagaga cggaagctcctgtag

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